0000000000393322

AUTHOR

Mark J. Tobin

showing 2 related works from this author

The role of melt-fracture degassing in defusing explosive rhyolite eruptions at volcán Chaitén

2012

Explosive volcanic eruptions of silicic magma often evolve towards non-explosive emissions of lava. The mechanisms underlying this transition remain unclear, however, a widely cited idea holds that shear-induced magma fragmentation plays a critical role by fostering volatile loss from fragmentary magma and through ash-filled cracks termed tuffisite. We test this hypothesis by measuring H2O concentrations within glassy tuffisite from the 2008–2011 rhyolitic eruption at volcan Chaiten, Chile. We show that while H2O concentrations decrease next to tuffisite veins and at the margins of obsidian fragments, the depletions cannot account for the disparity in H2O between explosively and effusively …

Diffusion modelinggeographygeography.geographical_feature_categoryExplosive materialLavaGeochemistrySilicicVolcanologyGeophysicsVolcanoSpace and Planetary ScienceGeochemistry and PetrologyRhyoliteEarth and Planetary Sciences (miscellaneous)GeologyEarth and Planetary Science Letters
researchProduct

Infrared based saliva screening test for COVID‐19

2021

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented need for diagnostic testing that is critical in controlling the spread of COVID-19. We propose a portable infrared spectrometer with purpose-built transflection accessory for rapid point-of-care detection of COVID-19 markers in saliva. Initially, purified virion particles were characterized with Raman spectroscopy, synchrotron infrared (IR) and AFM-IR. A data set comprising 171 transflection infrared spectra from 29 subjects testing positive for SARS-CoV-2 by RT-qPCR and 28 testing negative, was modeled using Monte Carlo Double Cross Validation with 50 randomized test and model sets. The testing se…

SalivaMaterials scienceCoronavirus disease 2019 (COVID-19)Spectrophotometry InfraredInfraredPoint-of-care testingInfrared spectroscopy010402 general chemistry01 natural sciencesProof of Concept StudySensitivity and SpecificityCatalysisSpecimen HandlingCohort Studies03 medical and health sciences0302 clinical medicineCOVID-19 TestingSpectrophotometryChlorocebus aethiopsmedicineCOVID-19 diagnostic infrared spectroscopy Raman spectroscopy saliva SARS-CoV-2 virionsAnimalsHumansQDLeast-Squares AnalysisSalivaVero CellsMass screening030304 developmental biologyDetection limit0303 health sciencessalivaChromatographymedicine.diagnostic_test010405 organic chemistrySARS-CoV-2COVID-19Discriminant AnalysisGeneral Chemistry030206 dentistryGeneral Medicine0104 chemical sciences3. Good healthPoint-of-Care TestingMonte Carlo MethodATR-FTIRResearch ArticleAngewandte Chemie (International Ed. in English)
researchProduct