0000000000405922
AUTHOR
Bonura Celestino
La sorveglianza della malattia tubercolare in Sicilia: Valutazioni epidemiologiche e molecolari come strumenti a supporto della Sanità Pubblica
L’epidemiologia della Tubercolosi (TB) in Sicilia è in rapida evoluzione con un aumento dei casi nella popolazione di nazionalità non italiana. La tipizzazione molecolare dei ceppi di M. tuberculosis complex (MTBC) costituisce un insostituibile supporto alla conoscenza dei ceppi circolanti e delle correlazioni tra i casi di TB. MATERIALI E METODI: Sono stati presi in considerazione i flussi di dati correnti, in particolare i dati di notifica delle malattie infettive del Sistema Informativo delle Malattie Infettive (SIMI) regionale incrociando questi con i dati provenienti dalle Schede di Dimissione Ospedaliera (SDO) attraverso il metodo del capture - recapture. Grazie alle attività del Labo…
Polyclonal non multiresistant methicillin resistant Staphylococcus aureus isolates from clinical cases of infection occurring in Palermo, Italy, during a one-year surveillance period
Abstract Background The evolving epidemiology of methicillin resistant Staphylococcus aureus (MRSA) is characterized by the emergence of infections caused by non multiresistant MRSA carrying staphylococcal chromosomal cassette (SCC)mec IV or V in the healthcare settings. A molecular epidemiological analysis of non multiresistant MRSA isolates from four acute general hospitals was performed in Palermo, Italy, during a one year period. Methods For the purpose of the study, MRSA isolates were defined as non multiresistant when they were susceptible to at least three classes of non β-lactam antibiotics. Seventy-five isolates were submitted to antimicrobial susceptibility testing, multilocus seq…
MRSA ST22-IVa (EMRSA-15 clone) in Palermo, Italy
Summary: Epidemic spread of methicillin-resistant Staphylococcus aureus (MRSA) strains carrying the Staphylococcal Chromosomal Cassettes (SCC) mec type IV is being increasingly reported in many geographical areas. A survey to determine the prevalence and characteristics of MRSA SCCmec IV isolates identified in four general hospitals in Palermo, Italy, was carried out. During the period February–June 2009, SCCmec type IVa has been found in 12 out of 94 isolates. Nine isolates from all hospitals and all strains from a NICU outbreak occurring in the same period were attributed with the ST22-IVa (EMRSA-15) clone. In our setting, due to the changing MRSA epidemiology, detection of SCCmec IV coul…