0000000000414246
AUTHOR
G. De Vita
showing 10 related works from this author
The importance of HCV on the burden of chronic liver disease in Italy: a multicenter prevalence study of 9,997 cases
2005
Knowledge of the current epidemiology of chronic liver disease in Italy is mostly obsolete and fragmentary for the lack of up-to-date consistent data. In 2001, a 6-month prevalence study was undertaken in 79 hospitals to assess the characteristics of chronic liver disease in Italy. Both prevalent and incident cases were enrolled. A total of 9,997 patients were recruited, of whom 939 (9.4%) had normal liver biochemistry, 6,210 (62.1%) had chronic hepatitis, 1,940 (19.4%) had liver cirrhosis, and 341 (3.4%) had hepatocellular carcinoma (HCC). In 567 patients (5.7%) the diagnosis was not established. Hepatitis C virus (HCV) was found in 69.9% of the patients and was the only etiological factor…
Laparoscopic drainage of liver abscess: case report and literature review.
2013
Aim To evaluate the safety and efficacy of the minimally invasive surgical approach (laparoscopic drainage) of liver abscesses in selected cases. Case report Male, 58 years old, from a rural area, presented with epigastric abdominal pain, fever, weight loss, loss of appetite, a palpable mass in the epigastrium and neutrophilic leukocytosis. CT revealed a complex multiloculated liver abscess in segments 2-3. Systemic antibiotic therapy alone was ineffective; percutaneous drainage was excluded due to the characteristics of the lesion. Result Given the complexity of the lesion, a laparoscopic approach was chosen involving complete drainage of the abscess, debridement and irrigation; the cavity…
DEPFET based Instrumentation for the MIXS focal plane on BepiColombo
2009
BepiColombo, ESA's fifth cornerstone mission, is a planetary exploration mission to Mercury. On board of BepiColombo's Mercury Planetary Orbiter (MPO), the MIXS instrument will perform a complete X-ray fluorescence analysis of Mercury's crust with unprecedented spectral and spatial resolution. This is achieved by using a lightweight X-ray mirror system and by using of DEPFET based Macropixel devices as X-ray detectors. DEPFET based Macropixel detectors combine the advantages of the DEPFETs, like flexible readout modes, Fano-limited energy resolution and low power consumption, with the properties of the drift detectors, like arbitrary scalable pixel size and geometry. In addition, the excell…
Sustainability evaluation of Sicily's lemon and orange production: An energy, economic and environmental analysis
2013
The island of Sicily has a long standing tradition in citrus growing. We evaluated the sustainability of orange and lemon orchards, under organic and conventional farming, using an energy, environmental and economic analysis of the whole production cycle by using a life cycle assessment approach. These orchard systems differ only in terms of a few of the inputs used and the duration of the various agricultural operations. The quantity of energy consumption in the production cycle was calculated by multiplying the quantity of inputs used by the energy conversion factors drawn from the literature. The production costs were calculated considering all internal costs, including equipment, materi…
The DEPFET based Focal Plane Detectors for MIXS on BepiColombo
2010
X-ray detectors based on arrays of DEPFET macropixels, which consist of a silicon drift detector combined with a detector/amplifier structure DEPFET as readout node, provide a convenient and flexible way to adapt the pixel size of a focal plane detector to the resolving power of any given X-ray optical system. Macropixels combine the traditional benefits of an SDD, like scalability, arbitrary geometry and excellent QE even in the low energy range, with the advantages of DEPFET structures: Charge storage capability, near Fano-limited energy resolution, low power consumption and high speed readout. Being part of the scientific payload of ESA's BepiColombo mission, the MIXS instrument will be …
The Wide Field Imager of the International X-ray Observatory
2010
The International X-ray Observatory (IXO) will be a joint X-ray observatory mission by ESA, NASA and JAXA. It will have a large effective area (3 m 2 at 1.25 keV) grazing incidence mirror system with good angular resolution (5 arcsec at 0.1–10 keV) and will feature a comprehensive suite of scientific instruments: an X-ray Microcalorimeter Spectrometer, a High Time Resolution Spectrometer, an X-ray Polarimeter, an X-ray Grating Spectrometer, a Hard X-ray Imager and a Wide-Field Imager. The Wide Field Imager (WFI) has a field-of-view of 18 ft � 18 ft. It will be sensitive between 0.1 and 15 keV, offer the full angular resolution of the mirrors and good energy resolution. The WFI will be imple…
The wide field imager for the International X-ray Observatory
2009
The large collecting area of the X-ray optics on the International X-ray Observatory (IXO), their good angular resolution, the wide bandwidth of X-ray energies and the high radiation tolerance required for the X-ray detectors in the focal plane have stimulated a new development of devices which unify all those science driven specifications in one single detector. The concept of a monolithic, back-illuminated silicon active pixel sensor (APS) based on the DEPFET structure is proposed for the IXO mission, being a fully depleted, back-illuminated 450 μm thick detector with a physical size of about 10 × 10 cm 2 corresponding to the 18 arcmin field of view. The backside will be covered with an i…
The aetiology of chronic hepatitis in Italy: results from a multicentre national study
2004
Background: No recent national-level data on the aetiology of chronic hepatitis are available in Italy. Aim: To evaluate the current aetiology of chronic hepatitis in Italy. Patients: A total of 6210 chronic hepatitis patients (both prevalence and incident cases) consecutively admitted to 79 hospitals located throughout Italy were enrolled over a 6-month period in 2001. The hospitals were randomly selected through systematic cluster sampling. Results: The main agent associated with chronic hepatitis was hepatitis C virus, which was found in 76.5% of the patients (in 62.6% it was the only aetiologic factor). Hepatitis B surface antigen was present in the serum of 12.2% of the cases (in 9.2% …
HCV infection is a risk factor for gallstone disease in liver cirrhosis: an Italian epidemiological survey
2007
We assessed the prevalence of gallbladder disease (i.e. gallstones plus cholecystectomy) among patients with liver disease and its association with the severity and aetiology of hepatic injury. Subjects, referred to 79 Italian hospitals, were enrolled in a 6-month period. The independent effect of the severity and aetiology of liver disease on gallstone disease prevalence was assessed by multiple logistic regression analysis. Overall, 4867 subjects tested anti-hepatitis C virus (HCV) positive alone, 839 were hepatitis B virus surface antigen (HBsAg) alone, and 652 had an excessive alcohol intake. The prevalence of gallstone disease was 23.3% in anti-HCV-positive patients, 12.4% in HBsAg pos…
Chronic hepatitis B in Italy: New features of an old disease - Approaching the universal prevalence of hepatitis B e antigen-negative cases and the e…
2008
We evaluated 1336 hepatitis B surface antigen-positive subjects consecutively observed in 79 Italian hospitals over a 6-month period. The proportion of hepatitis B e antigen-negative cases was 86.4%, that of patients coinfected with hepatitis D virus was 9.7%, and the rate of patients coinfected with hepatitis C virus was 16.8%. Multiple logistic regression analysis showed that age >49 years, alcohol abuse, and anti-hepatitis D virus and anti-hepatitis C virus positivity were independent predictors of progression to liver cirrhosis. © 2007 by the Infectious Diseases Society of America. All rights reserved.