0000000000414276

AUTHOR

C. Galassi

showing 3 related works from this author

Effects of pet exposure in the first year of life on respiratory and allergic symptoms in 7-yr-old children. The SIDRIA-2 study

2010

Lombardi E, Simoni M, La Grutta S, Viegi G, Bisanti L, Chellini E, Dell’Orco V, Migliore E, Petronio MG, Pistelli R, Rusconi F, Sestini P, Forastiere F, Galassi C and the SIDRIA-2 Collaborative Group. Effects of pet exposure in the first year of life on respiratory and allergic symptoms in 7-yr-old children. The SIDRIA-2 study. Pediatr Allergy Immunol 2010: 21: 268–276. © 2009 John Wiley & Sons A/S The effects of pet exposure on the development of respiratory symptoms have recently been the matter of vivid discussion. Our objective was to determine the effects of exposure to cat or dog in the first year of life on subsequent respiratory/allergic symptoms in children in a large Italian multi…

MaleAllergyPediatricsPassive smokingRespiratory Tract DiseasesEczemamedicine.disease_causeAnimals; Respiratory Sounds; Fungi; Humans; Asthma; Rhinitis; Child; Eczema; Italy; Smoking; Hypersensitivity; Respiratory Tract Diseases; Risk Factors; Cats; Environmental Exposure; Dogs; Female; MaleRisk FactorsDogImmunology and AllergyFamily historyChildRespiratory Tract DiseaseRhinitiRhinitismedicine.diagnostic_testRespiratory diseaseSmokingCatschoolchildrenEnvironmental exposureItalyFemaleepidemiologyHumanmedicine.medical_specialtyImmunologyDogsmedicineHypersensitivityAnimalsHumansRespiratory soundsRisk factorAsthmaRespiratory Soundsasthma; schoolchildren; epidemiologybusiness.industryAnimalRisk FactorFungiEnvironmental Exposureasthmamedicine.diseasePediatrics Perinatology and Child HealthImmunologyCatsRespiratory Soundbusiness
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Air pollution and childhood leukaemia: a nationwide case-control study in Italy

2013

Objectives Leukaemia is the most common cancer in children, but its aetiology is still poorly understood. We tested the hypothesis that traffic-related air pollution is associated with paediatric leukaemia because of chronic exposure to several potential carcinogens. Methods The Italian SETIL study (Study on the aetiology of lymphohematopoietic malignancies in children) was conducted in 14 Italian regions. All incident cases of leukaemia in children aged ≤10 years from these regions (period 1998–2001) were eligible for enrolment. Two controls per case, matched on birth date, gender and region of residence were randomly selected from the local population registries. Exposure assessment at bi…

MalePediatricsAir pollutionNO2Land use Regression ModelLogistic regressionmedicine.disease_causeEconomicaResidence CharacteristicsUSE REGRESSION-MODELSMedicineChildChildrenVehicle EmissionsGeneral Environmental ScienceUSE REGRESSION-MODELS RESIDENTIAL TRAFFIC DENSITY MAGNETIC-FIELDS POOLED ANALYSIS RISK-FACTOR CANCER EXPOSURE CHILDREN NO2 ASSOCIATIONLeukemiaIncidenceIncidence (epidemiology)ASSOCIATIONCANCERChildhood leukaemiaItalyChild PreschoolFemaleCase-Control StudieHumanmedicine.medical_specialtySocio-culturaleMAGNETIC-FIELDSPOOLED ANALYSISRISK-FACTORAir PollutionOccupational ExposureEnvironmental healthTraffic IndicatorHumansEXPOSURERESIDENTIAL TRAFFIC DENSITYExposure assessmentVehicle Emissionbusiness.industryPublic Health Environmental and Occupational HealthCase-control studyAmbientaleInfantCarcinogens EnvironmentalAutomobileCase-Control StudiesResidence CharacteristicDispersion ModelEtiologyGeneral Earth and Planetary SciencesParticulate MatterResidencebusinessAutomobilesOccupational and Environmental Medicine
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Perturbation of metabolic pathways mediates the association of air pollutants with asthma and cardiovascular diseases.

2018

Background: Epidemiologic evidence indicates common risk factors, including air pollution exposure, for respiratory and cardiovascular diseases, suggesting the involvement of common altered molecular pathways. Objectives: The goal was to find intermediate metabolites or metabolic pathways that could be associated with both air pollutants and health outcomes (“meeting-in-the-middle”), thus shedding light on mechanisms and reinforcing causality. Methods: We applied a statistical approach named ‘meet-in-the-middle’ to untargeted metabolomics in two independent case-control studies nested in cohorts on adult-onset asthma (AOA) and cardio-cerebrovascular diseases (CCVD). We compared the results …

Air pollution Untargeted metabolomics Metabolic pathways Adult-onset asthma Cardio-cerebrovascular diseases0301 basic medicineChronic exposureAdultAir pollution exposureAir pollutionAir pollution010501 environmental sciencesmedicine.disease_cause01 natural sciencesSettore MED/01 - Statistica Medica03 medical and health sciencesAir pollutantsMD MultidisciplinarymedicineHumans0105 earth and related environmental sciencesGeneral Environmental ScienceAsthmaCardio-cerebrovascular diseasesAir PollutantsUntargeted metabolomicsOdds ratioEnvironmental Exposuremedicine.diseaseAsthmaMetabolic pathway030104 developmental biologyUntargeted metabolomicsMetabolic pathwaysCardiovascular DiseasesCase-Control StudiesImmunologyEXPOsOMICS ConsortiumEnvironmental SciencesMetabolic Networks and PathwaysAdult-onset asthmaEnvironment international
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