0000000000418871

AUTHOR

Alessandro Livi

showing 2 related works from this author

Chronic neural probe for simultaneous recording of single-unit, multi-unit, and local field potential activity from multiple brain sites

2017

Drug resistant focal epilepsy can be treated by resecting the epileptic focus requiring a precise focus localisation using stereoelectroencephalography (SEEG) probes. As commercial SEEG probes offer only a limited spatial resolution, probes of higher channel count and design freedom enabling the incorporation of macro and microelectrodes would help increasing spatial resolution and thus open new perspectives for investigating mechanisms underlying focal epilepsy and its treatment. This work describes a new fabrication process for SEEG probes with materials and dimensions similar to clinical probes enabling recording single neuron activity at high spatial resolution.Polyimide is used as a bi…

focal epilepsyMaterials scienceFocus (geometry)SEEGBiomedical EngineeringPosterior parietal cortexFOS: Physical sciencesBiocompatible Materials02 engineering and technologyLocal field potentialchronic; depth neural probe; focal epilepsy; in vivo; SEEG; single unit activity; stereoelectroencephalography; Biomedical Engineering; Cellular and Molecular NeuroscienceStereoelectroencephalographystereoelectroencephalography03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicineParietal LobeAnimalsMulti unitImage resolutionEvoked PotentialsNeuronsBrainElectroencephalography021001 nanoscience & nanotechnologyPhysics - Medical PhysicsMacaca mulattadepth neural probesingle unit activityElectrodes ImplantedchronicMicroelectrodein vivoQuantitative Biology - Neurons and CognitionFOS: Biological sciencesElectrodeFemaleNeurons and Cognition (q-bio.NC)Epilepsies PartialMedical Physics (physics.med-ph)0210 nano-technologyMicroelectrodes030217 neurology & neurosurgeryBiomedical engineering
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Comparative Performance of Linear Multielectrode Probes and Single-Tip Electrodes for Intracortical Microstimulation and Single-Neuron Recording in M…

2017

Intracortical microstimulation (ICMS) is one of the most widely employed techniques for providing causal evidence of the relationship between neuronal activity and specific motor, perceptual, or even cognitive functions. In recent years, several new types of linear multielectrode silicon probes have been developed, allowing researchers to sample neuronal activity at different depths along the same cortical site simultaneously and with high spatial precision. Nevertheless, silicon multielectrode probes have been rarely employed for ICMS studies and, more importantly, it is unknown whether and to what extent they can be used for combined recording and stimulation experiments. Here, we address…

0301 basic medicineHand regionMaterials scienceCognitive NeuroscienceNeuroscience (miscellaneous)Acute recording; Chronic recording; Electrical stimulation; Macaque monkey; Silicon probes; Neuroscience (miscellaneous); Developmental Neuroscience; Cognitive Neuroscience; Cellular and Molecular NeuroscienceMacaquechronic recording03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicineDevelopmental Neurosciencebiology.animalmedicinePremovement neuronal activitysilicon probeselectrical stimulationOriginal Researchbiologytechnology industry and agricultureequipment and suppliesmacaque monkeyMicroelectrode030104 developmental biologyIntracortical microstimulationmedicine.anatomical_structureElectrodeacute recordingNeuron030217 neurology & neurosurgeryBiomedical engineeringMotor cortexNeuroscienceFrontiers in systems neuroscience
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