0000000000419714

AUTHOR

Emilio I. Alarcon

showing 3 related works from this author

Gold nanoparticle catalysis of the cis-trans isomerization of azobenzene

2013

Ablated, “pseudo-naked” gold nanoparticles (AuNPs) catalyze the cis–trans isomerization of substituted azobenzenes. para-Substitution was found to affect the rate of isomerization, suggesting the participation of AuNP-mediated electron transfer in the isomerization mechanism. Fil: Hallet Tapley, Geniece. University of Ottawa; Canadá Fil: D'Alfonso, Claudio. University of Ottawa; Canadá. Universita Di Roma; Italia Fil: Pacioni, Natalia Lorena. University of Ottawa; Canadá Fil: McTiernan, Cristopher D.. University of Ottawa; Canadá Fil: Gonzalez Bejar, Maria. University of Ottawa; Canadá. Universidad de Valencia; España Fil: Lanzalunga, Osvaldo. Universita Di Roma; Italia Fil: Alarcon, Emilio…

NanoparticleNANOCATALYSIS010402 general chemistryPhotochemistry01 natural sciencesCatalysisCatalysisElectron transferchemistry.chemical_compoundMaterials ChemistryGOLDISOMERIZATION010405 organic chemistryChemistryOtras Ciencias QuímicasCiencias QuímicasMetals and AlloysGeneral ChemistryCis trans isomerization0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsAZOBENZENESAzobenzeneColloidal goldCeramics and CompositesIsomerizationCIENCIAS NATURALES Y EXACTAS
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NIR excitation of upconversion nanohybrids containing a surface grafted Bodipy induces oxygen-mediated cancer cell death

2020

We report the preparation of water-dispersible, ca. 30 nm-sized nanohybrids containing NaYF4:Er3+, Yb3+ up-conversion nanoparticles (UCNPs), capped with a polyethylene glycol (PEG) derivative and highly loaded with a singlet oxygen photosensitizer, specifically a diiodo-substituted Bodipy (IBDP). The photosensitizer, bearing a carboxylic group, was anchored to the UCNP surface and, at the same time, embedded in the PEG capping; the combined action of the UCNP surface and PEG facilitated the loading for an effective energy transfer and, additionally, avoided photosensitizer leaching from the nanohybrid (UCNP-IBDP@PEG). The effectiveness of the nanohybrids in generating singlet oxygen after n…

Materials scienceSinglet oxygentechnology industry and agricultureBiomedical Engineeringchemistry.chemical_elementNanoparticleGeneral ChemistryGeneral MedicinePolyethylene glycolPhotochemistryOxygenPhoton upconversionchemistry.chemical_compoundchemistryPEG ratioGeneral Materials SciencePhotosensitizerBODIPYJ. Mater. Chem. B
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Ketorolac beats ketoprofen: lower photodecarboxylation, photohemolysis and phototoxicity

2013

Ketorolac shows reduced photohemolytic activity and low phototoxicity against human skin fibroblasts when compared to ketoprofen. The low decarboxylation quantum yield together with the efficient non-radiative deactivation of the triplet and singlet excited states of ketorolac are believed to be responsible for this behaviour.

PharmacologyKetoprofenDecarboxylationChemistryOrganic ChemistryPharmaceutical ScienceQuantum yieldHuman skinPharmacologyPhotochemistryBiochemistryKetorolacExcited stateDrug DiscoverymedicineMolecular MedicineSinglet statePhototoxicitymedicine.drugMedChemComm
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