0000000000431496

AUTHOR

Esther Gracia-lavedan

showing 7 related works from this author

Drinking water disinfection by-products, genetic polymorphisms, and birth outcomes in a european mother-child cohort study

2016

Background: We examined the association between exposure during pregnancy to trihalomethanes, the most common water disinfection by-products, and birth outcomes in a European cohort study (Health Impacts of Long-Term Exposure to Disinfection By-Products in Drinking Water). We took into account exposure through different water uses, measures of water toxicity, and genetic susceptibility. Methods: We enrolled 14,005 mothers (2002-2010) and their children from France, Greece, Lithuania, Spain, and the UK. Information on lifestyle-and water-related activities was recorded. We ascertained residential concentrations of trihalomethanes through regulatory records and ad hoc sampling campaigns and e…

MaleEpidemiology010501 environmental sciences01 natural sciencesCohort Studies0302 clinical medicinePregnancyRisk Factors030212 general & internal medicineProspective StudiesProspective cohort studyComputingMilieux_MISCELLANEOUS2. Zero hungerStatisticsPregnancy Outcome3. Good healthEuropeMaternal ExposureInfant Small for Gestational AgePremature BirthFemalemedicine.symptomCohort studyTrihalomethanesGenetic MarkersDNA Copy Number VariationsBirth weightPublic Health And Health ServicesPolymorphism Single Nucleotide03 medical and health sciencesEnvironmental healthmedicineHumans0105 earth and related environmental sciences[SDV.EE.SANT]Life Sciences [q-bio]/Ecology environment/HealthPregnancybusiness.industryDrinking WaterCase-control studyInfant NewbornOdds ratioInfant Low Birth Weightmedicine.diseaseDisinfectionLow birth weightCase-Control StudiesSmall for gestational ageGene-Environment InteractionbusinessWater Pollutants ChemicalDisinfectants
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Correction: Association of ionizing radiation dose from common medical diagnostic procedures and lymphoma risk in the Epilymph case-control study

2020

International audience; Medical diagnostic X-rays are an important source of ionizing radiation (IR) exposure in the general population; however, it is unclear if the resulting low patient doses increase lymphoma risk. We examined the association between lifetime medical diagnostic X-ray dose and lymphoma risk, taking into account potential confounding factors, including medical history. The international Epilymph study (conducted in the Czech-Republic, France, Germany, Ireland, Italy, and Spain) collected self-reported information on common diagnostic X-ray procedures from 2,362 lymphoma cases and 2,465 frequency-matched (age, sex, country) controls. Individual lifetime cumulative bone mar…

MaleLimfomesLymphoma[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/ImagingPhysiologyLogistic regressionPediatrics030218 nuclear medicine & medical imagingDiagnostic RadiologyHematologic Cancers and Related Disorders0302 clinical medicineRisk FactorsBone MarrowRadiation IonizingImmune PhysiologyOdds RatioMedicine and Health SciencesMedicineFamily historyCàncerCancerCancer risk factorseducation.field_of_studyMultidisciplinaryFactors de risc en les malaltiesRadiology and ImagingQConfoundingRHematologyMiddle AgedRadiation ExposureBone Imaging3. Good healthOncology030220 oncology & carcinogenesisMedicineFemaleLymphomasResearch ArticleAdultmedicine.medical_specialtyRisk factors in diseasesImaging TechniquesSciencePopulationImmunology[SDV.CAN]Life Sciences [q-bio]/CancerRadiation DosageResearch and Analysis Methods03 medical and health sciences[SDV.CAN] Life Sciences [q-bio]/CancerRheumatologyDiagnostic MedicineInternal medicineOsteoarthritisCancer Detection and DiagnosisHumansMedical historyeducationAgedbusiness.industryArthritisCase-control studyCorrectionCancers and NeoplasmsBiology and Life SciencesOdds ratiomedicine.diseaseLymphomaX-Ray RadiographyMedical risk factorsLogistic Models[SDV.IB.IMA] Life Sciences [q-bio]/Bioengineering/Imaging[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologieCase-Control StudiesImmune System[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologiebusinessPLoS ONE
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Water hardness and eczema at 1 and 4 y of age in the INMA birth cohort.

2015

Abstract Background: Exposure to hard water has been suggested as a risk factor for eczema in childhood, based on limited evidence from two ecologic and two cross-sectional studies. Objectives: We evaluate this hypothesis for the first time in early infancy using prospective data from a mother–child cohort study. Methods: We used data from the INMA cohorts in Gipuzkoa, Sabadell and Valencia, Spain (N=1638). Current and ever eczema, bathing frequency and duration and covariables were collected by questionnaires at 14 months (14 m) and 4 years (4 y). Calcium carbonate (CaCO3) level in municipal water was assigned to home addresses at birth, 14 m and 4 y. We calculated Odds Ratio (OR) of eczem…

AdultMalePediatricsmedicine.medical_specialtyBathingEczemaBiochemistryCohort StudiesRisk FactorsMedicineHumansRisk factorGeneral Environmental ScienceExposure assessmentbusiness.industryHard waterInfantWaterOdds ratioEnvironmental exposureAtopic dermatitisEnvironmental Exposuremedicine.diseaseSpainChild PreschoolFemalebusinessCohort studyDemographyEnvironmental research
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Exposure to trihalomethanes through different water uses and birth weight, small for gestational age, and preterm delivery in Spain

2011

Background: Evidence associating exposure to water disinfection by-products with reduced birth weight and altered duration of gestation remains inconclusive. Objective: We assessed exposure to trihalomethanes (THMs) during pregnancy through different water uses and evaluated the association with birth weight, small for gestational age (SGA), low birth weight (LBW), and preterm delivery. Methods: Mother–child cohorts set up in five Spanish areas during the years 2000–2008 contributed data on water ingestion, showering, bathing, and swimming in pools. We ascertained residential THM levels during pregnancy periods through ad hoc sampling campaigns (828 measurements) and regulatory data (264 me…

PediatricsFetus -- CreixementBathingHealth Toxicology and MutagenesisEspaña:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Cohort Studies:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models Theoretical [Medical Subject Headings]small for gestational agePregnancynewbornFemeninosExposición a Riesgos Ambientales:Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy [Medical Subject Headings]:Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings]water pollutionInfeccions respiratòries -- EpidemiologiaAdultodisinfection by-products:Named Groups::Persons::Age Groups::Infant::Infant Newborn::Infant Low Birth Weight [Medical Subject Headings]Modelos TeóricosEnvironmental exposurepremature birthNacimiento PrematuroHumanos:Health Care::Environment and Public Health::Public Health::Environmental Pollution::Environmental Exposure [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models Statistical::Logistic Models [Medical Subject Headings]Premature birthInfant Small for Gestational AgeGestation:Named Groups::Persons::Age Groups::Infant::Infant Newborn::Infant Low Birth Weight::Infant Small for Gestational Age [Medical Subject Headings]Femaleepidemiologymedicine.symptomAigua -- DepuracióAdultmedicine.medical_specialtytrihalomethanesContaminantes Químicos del AguaEmbarazoBirth weight:Named Groups::Persons::Age Groups::Infant::Infant Newborn [Medical Subject Headings]Embaràs -- Aspectes nutricionalsRecién nacidoRecién Nacido Pequeño para la Edad GestacionalEnvironmental healthmedicine:Named Groups::Persons::Age Groups::Adult [Medical Subject Headings]cohort studyModelos LogísticosHumanslow birth weightEpidemiologiaRecién Nacido de Bajo Peso:Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons Halogenated::Trihalomethanes [Medical Subject Headings]Pregnancybusiness.industryTrihalometanoResearchPublic Health Environmental and Occupational HealthInfant Newbornbirth weightEnvironmental ExposureInfant Low Birth WeightModels Theoreticalmedicine.diseaseLow birth weightLogistic Models:Check Tags::Female [Medical Subject Headings]Spain:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies [Medical Subject Headings]Small for gestational age:Chemicals and Drugs::Chemical Actions and Uses::Toxic Actions::Environmental Pollutants::Water Pollutants::Water Pollutants Chemical [Medical Subject Headings]:Diseases::Female Urogenital Diseases and Pregnancy Complications::Pregnancy Complications::Obstetric Labor Complications::Obstetric Labor Premature::Premature Birth [Medical Subject Headings]businessEstudios de CohortesWater Pollutants Chemical
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Nonparticipation Selection Bias in the MOBI-Kids Study.

2018

Supplemental Digital Content is available in the text.

GerontologyMaleAdolescentCellular telephone useEpidemiologyCase–control studymedia_common.quotation_subjectEpidemiologic methodsAdolescents01 natural sciencesBrain tumorsBrain cancer010104 statistics & probability03 medical and health sciencesYoung Adult0302 clinical medicineElectromagnetic FieldsAge groupsBiasJapanRisk FactorsGermanySurveys and QuestionnairesPerinatal and Child HealthOdds RatioHumans030212 general & internal medicine0101 mathematicsIsraelChildChildrenmedia_commonSelection biasSelection biasBrain NeoplasmsCase-control studyItalySpainCase-Control StudiesComputingMethodologies_DOCUMENTANDTEXTPROCESSINGFemaleFrancePsychologyCell PhoneEpidemiology (Cambridge, Mass.)
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Drinking water disinfection by-products during pregnancy and child neuropsychological development in the INMA Spanish cohort study.

2017

Background: Disinfection by-products (DBPs) constitute a complex mixture of prevalent chemicals in drinking water and there is evidence of neurotoxicity for some of them. Objectives: We evaluated the association between estimates of DBP exposure during pregnancy and child neuropsychological outcomes at 1 and 4–5 years of age. Methods: We conducted a population-based mother-child cohort study in Spain with recruitment at first trimester of gestation (INMA Project, 2003–2008). Neuropsychological development was measured at 1 year of age using the Bayley Scales of Infant Development and at 4–5 years with the McCarthy Scales of Children's Abilities. Modeled tap water concentrations of trihalome…

MaleHaloacetic acidsBathingNeurodevelopmentPhysiology010501 environmental sciencesBromodichloromethane01 natural sciencesBayley Scales of Infant DevelopmentCohort Studieschemistry.chemical_compound0302 clinical medicineDisinfection by-productsChild DevelopmentPregnancyIngestionChildrenlcsh:Environmental sciencesGeneral Environmental Science2. Zero hungerlcsh:GE1-350education.field_of_study3. Good healthMaternal ExposureEnvironmental chemistryChild PreschoolFemalemedicine.drugTrihalomethanesAdultDibromochloromethanePopulation03 medical and health sciencesWater SupplymedicineHumanseducation0105 earth and related environmental sciencesPregnancyHaloacetic acidsDrinking WaterWaterInfantmedicine.diseasechemistrySpainNervous System Diseases030217 neurology & neurosurgeryWater Pollutants ChemicalDisinfectantsEnvironment international
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Postnatal weight growth and trihalomethane exposure during pregnancy.

2014

Abstract Background Impaired postnatal growth after chloroform exposure in utero has been observed in rodents without an effect on birth weight. We aimed to study the relationship between exposure to trihalomethanes (THMs) during pregnancy and postnatal weight growth during infancy. Methods We analysed 2216 mother–child pairs recruited in Gipuzkoa, Sabadell, Valencia (Spain, INMA Project, enrolment: 2003–2008) and Crete (Greece, RHEA Study, enrolment: 2007–2008). Drinking water habits and water-related activities ascertained through personal interviews were combined with THM measurements in drinking water to estimate THM exposure through different exposure routes during pregnancy. Weight me…

Malemedicine.medical_specialtyBirth weightGrowthBiochemistryInterquartile rangePregnancyMedicineIngestionHumansGeneral Environmental SciencePregnancybusiness.industryObstetricsConfoundingInfant Newbornmedicine.diseaseIn uteroMaternal ExposureFemalemedicine.symptombusinessWeight gainCohort studyDemographyTrihalomethanesEnvironmental research
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