0000000000460651

AUTHOR

Vita Giaccone

0000-0003-4025-0699

showing 4 related works from this author

Oxidation resistance of LDL is correlated with vitamin E status in beta-thalassemia intermedia.

1998

The alteration of the oxidant/antioxidant balance may affect the susceptibility of low density lipoproteins (LDL) to oxidation in haemolytic disorders such as thalassemia. Thirty patients affected by beta-thalassemia intermedia were examined, and compared with age-matched healthy controls. The mean amount of vitamin E in the thalassemic LDL was lower than control (p0.0001), either when it was calculated on the base of LDL protein (61% decrease) or cholesterol (25% decrease). The LDL resistance to Cu2+-induced oxidation, evaluated as the length of the lag phase before the onset of conjugated diene (CD) lipid hydroperoxide production, was 20% lower than control. Other parameters of LDL suscep…

Hemolytic anemiaAdultMalemedicine.medical_specialtyAntioxidantmedicine.medical_treatmentThalassemiaOxidative phosphorylationmedicine.disease_causeLipid peroxidationchemistry.chemical_compoundInternal medicinemedicineHumansVitamin ECholesterolVitamin Ebeta-ThalassemiaMiddle Agedmedicine.diseaseLipoproteins LDLOxidative StressEndocrinologyCholesterolchemistryRegression Analysislipids (amino acids peptides and proteins)FemaleLipid PeroxidationCardiology and Cardiovascular MedicineOxidation-ReductionOxidative stressFollow-Up StudiesAtherosclerosis
researchProduct

Mercury in fish products: what’s the best for consumers between bluefin tuna and yellowfin tuna?

2017

A total of 205 bluefin and yellowfin tuna samples were examined for mercury detection in order to verify possible differences and have a detailed risk assessment of the two tuna species. The results showed significant higher mercury concentration in muscle tissue of bluefin tuna respect yellowfin tuna (p < 0.001) with mean concentration of 0.84 mg/kg and maximum value of 1.94 mg/kg. These differences can be due the different biological and ecological aspects of the two tuna species and to different oceanographic aspects between Atlantic Ocean and Mediterranean sea. The results obtained in this study suggest an advisable containment of the sources of pollution and further studies on the c…

Yellowfin tunachemistry.chemical_elementFood ContaminationPlant ScienceRisk Assessment01 natural sciencesBiochemistryAnalytical Chemistrybluefin tuna; fish products; heavy metals; Mercury; mercury direct analyser; yellowfin tuna; Analytical Chemistry; Biochemistry; Plant Science; Organic ChemistryPlant scienceMediterranean seaFish Productsfish productMediterranean SeaAnimalsHumansAtlantic OceanbiologyMercury in fishTuna010405 organic chemistryMusclesOrganic Chemistrymercury direct analyseryellowfin tunafood and beveragesHeavy metalsEnvironmental ExposureMercuryheavy metalbiology.organism_classificationFish products0104 chemical sciencesMercury (element)Fishery010404 medicinal & biomolecular chemistrychemistrybluefin tunaEnvironmental scienceTunahuman activitiesFood AnalysisWater Pollutants Chemical
researchProduct

Analysis of β2-agonists in cattle hair samples using a rapid UHPLC–ESI–MS/MS method

2016

A simple and efficient method was developed for simultaneous analysis of five illegal residual β2-agonists in cattle hair. β2-Agonists were quantified by ultra high performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry operating in positive multiple-reaction monitoring mode. The method was validated as quantitative confirmatory method according to the EU Decision 2002/657/EC: instrumental linearity, specificity, precision, recovery, decision limit (CCα) and detection capability (CCβ) were evaluated. The recovery were greater than 90% and the method appeared suitable for the control of these β2-agonists in cattle hair samples with LOQ values between …

UHPLC –ESI–MS/MSβ2-agonist0301 basic medicineElectrospray030109 nutrition & dieteticsChromatographycattle hair; Commission Decision 2002/657/EC; UHPLC–ESI–MS/MS; β2-agonists; Plant Science; Biochemistry; Analytical Chemistry; Organic ChemistryChemistryβ2 agonistsElectrospray ionization010401 analytical chemistryOrganic ChemistryPlant ScienceContaminationTandem mass spectrometry01 natural sciencesBiochemistry0104 chemical sciencesAnalytical Chemistry03 medical and health sciencesCommission Decision 2002/657/ECcattle hairAdrenergic beta-AgonistsUltra high performanceDecision limitNatural Product Research
researchProduct

First report on the presence of Alloxan in bleached flour by LC-MS/MS method

2017

Abstract In this work the presence of Alloxan in bread, pastry and cake bleached flour was investigate in order to verify possible risk for consumers related to the use of chemicals for flour bleaching. A selective UHPLC–MS/MS method has been developed and validated for the purpose. Alloxan is one of the possible minor side products of oxidation after chemical bleaching of wheat flours, when several chemical agents are used. One hundred and seventy-five flour samples were analyzed for Alloxan determination. The validation of the method was performed in accordance with the ISO/IEC/EN 17025 for linearity, detection limit, quantification limit, accuracy, precision and ruggedness determination.…

0301 basic medicineDetection limitAnalyteChromatographybakery productsSettore CHIM/10 - Chimica Degli AlimentiLC–ESI-MS/MSFlour030209 endocrinology & metabolismFlour Alloxan LC–ESI-MS/MS Validation procedure Bakery productsBiochemistry03 medical and health scienceschemistry.chemical_compound030104 developmental biology0302 clinical medicinechemistryChemical agentsAlloxanLc ms msAlloxanFlour AlloxanBakery productsValidation procedurevalidation procedureFood Science
researchProduct