0000000000461967

AUTHOR

Raghu Radhakrishnan

showing 3 related works from this author

CD1a+ and CD207+ cells are reduced in oral submucous fibrosis and oral squamous cell carcinoma

2019

Background The objective of this study investigated the distribution of immature dendritic cells (DCs), Langerhans cells and plasmacytoid DCs in oral submucous fibrosis (OSMF), OSMF associated with oral squamous cell carcinoma (OSMF-OSCC), oral leukoplakia (OL), and oral squamous cell carcinoma (OSCC). Material and Methods Fourteen cases of OSMF, 9 of OSMF-OSCC, 8 of OL¸ 45 of OSCC and 8 of normal epithelium were retrospectively retrieved and their diagnoses confirmed. Immunoreactions against CD1a, CD207 e CD303 were performed and the number of positive cells quantified. Results A significant decrease of CD1a+ was found in OSMF (p≤0.05), OSMF-OSCC (p ≤ 0.01), and OSCC (p ≤ 0.001) when compa…

medicine.medical_specialtyOral Submucous FibrosisGastroenterologyMalignant transformation03 medical and health sciences0302 clinical medicineImmune systemAntigenAntigens CDInternal medicinemedicineCarcinomaHumansLectins C-TypeGeneral DentistryLeukoplakiaRetrospective StudiesMouth neoplasmOral Medicine and Pathologybusiness.industryResearch030206 dentistry:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseEpitheliumstomatognathic diseasesmedicine.anatomical_structureMannose-Binding LectinsOtorhinolaryngologyOral submucous fibrosisUNESCO::CIENCIAS MÉDICASCarcinoma Squamous CellSurgeryMouth NeoplasmsLeukoplakia OralbusinessMedicina Oral, Patología Oral y Cirugía Bucal
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Fibrous Dysplasia and Ossifying Fibroma-an advent in their diagnosis

2011

Objectives: Fibro-osseous lesions of the craniofacial complex comprise of a diverse, interesting and challenging group of conditions that pose difficulties in classification and treatment. The two most confused benign fibro-osseous lesions are fibrous dysplasia and ossifying fibroma. Sometimes, the classic clinical, radiologic or pathologic features of fibrous dysplasia or ossifying fibroma may not be evident, but overlapping features of both may be seen. The dilemma in diagnosis of these lesions rests in the bony trabeculae as well as in the fibrous stroma. Cases of fibrous dysplasia showing lamellated bony trabeculae and osteoblastic rimming have been reported which may confound diagnosis…

Pathologymedicine.medical_specialtybusiness.industryFibrous dysplasiaOdontologíaAnatomyOssifying fibromaHaematoxylin:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCiencias de la saludStainstomatognathic diseaseschemistry.chemical_compoundOxytalanchemistryTrichromeUNESCO::CIENCIAS MÉDICASMedicineTrichrome stainCraniofacialbusinessGeneral DentistryJournal of Clinical and Experimental Dentistry
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Quantification of colloid bodies in Oral Lichen Planus and Oral Lichenoid Reaction - A Histochemical Study

2011

Aim: Oral lichen planus and oral lichenoid reaction are familiar keratotic lesions found on the oral mucosa. Colloid bodies can be microscopically appreciated in both these lesions. The aim of this study was to identify as well as examine the frequency of colloid bodies in oral lichen planus and oral lichenoid reaction by histochemical means. Method: The material for the study included 12 formalin-fixed paraffin-embedded tissue blocks (7 oral lichen planus and 5 oral lichenoid reaction), retrieved from the Department of Oral Pathology and Microbiology, MCODS, Manipal. Sections stained with hematoxylin-eosin (H&E) and periodic acid-Schiff (PAS) with diastase to identify, locate and examine t…

medicine.medical_specialtyPathologyintegumentary systembusiness.industryColloid bodiesConnective tissueOral lichenoid reactionOdontologíamedicine.disease:CIENCIAS MÉDICAS [UNESCO]DermatologyCiencias de la saludstomatognathic diseasesmedicine.anatomical_structurestomatognathic systemOral and maxillofacial pathologyUNESCO::CIENCIAS MÉDICASmedicineOral lichen planusOral mucosabusinessskin and connective tissue diseasesGeneral Dentistry
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