0000000000465011

AUTHOR

Guido Krämer

showing 2 related works from this author

Generation of hexahydroazulenes

2009

(Z)-Cyclodec-1-en-6-yne (3) generates three conjugated hexahydroazulenes 3→1k→1c, 1l under FVP conditions, whereas flash vacuum pyrolysis (FVP) of cyclodecyne (2) leads to 1,2,9-decatriene (9). We attribute the different thermal behavior of 2 (ring opening) and 3 (ring closure) to different transannular interactions. Altogether 22 constitutional isomers of hexahydroazulene should exist; three new isomers (1k, 1l, and 1m) are presented here, ten were described earlier, but the reinvestigation of the dehydration route of bicyclic alcohol 11 showed that one of the ten structures has to be revised.

chemistry.chemical_compoundchemistryFlash vacuum pyrolysisBicyclic moleculeStereochemistryOrganic ChemistryDrug DiscoveryStructural isomerAlcoholConjugated systemRing (chemistry)BiochemistryMedicinal chemistryTetrahedron Letters
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Generation and transformation of the [3.3.1]propellane skeleton by thermal rearrangements

1994

Abstract In a sequence of unexpected thermal rearrangements the strained monocyclic alkyne 4 is transformed into the tricyclic system 5 which yields in a flash vacuum pyrolysis again a monocyclic compound 10 .

chemistry.chemical_classificationPropellanechemistry.chemical_compoundFlash vacuum pyrolysischemistryComputational chemistryOrganic ChemistryDrug DiscoveryThermalAlkynePhotochemistryBiochemistryTransformation (music)Tetrahedron Letters
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