0000000000466817

AUTHOR

A. Burguet

Does Embryo Culture Medium Influence the Health and Development of Children Born after In Vitro Fertilization?

International audience; In animal studies, extensive data revealed the influence of culture medium on embryonic development, foetal growth and the behaviour of offspring. However, this impact has never been investigated in humans. For the first time, we investigated in depth the effects of embryo culture media on health, growth and development of infants conceived by In Vitro Fertilization until the age of 5 years old. This single-centre cohort study was based on an earlier randomized study. During six months, in vitro fertilization attempts (No. 371) were randomized according to two media (Single Step Medium—SSM group) or Global medium (Global group). This randomized study was stopped prem…

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Le risque d’intubation des grands prématurés en salle de naissance est-il lié au type d’anesthésie maternelle ? Expérience des réseaux périnatals Poitou-Charentes et Franche-Comté

Resume Objectif Apprecier le taux d’intubation en salle de naissance des grands prematures nes par cesarienne avant travail, en fonction du type d’anesthesie maternelle (rachianesthesie versus anesthesie generale [AG]). Population et methode Deux cent dix-neuf grands prematures (28–32 semaines d’amenorrhee) nes vivants par cesarienne avant travail dans une des 27 maternites de 2 reseaux perinatals (Poitou-Charentes et Franche-Comte). Cent quatre-vingt-deux sur 219 (83 %) sont nes dans la maternite regionale de reference de type III. Resultats Parmi les grands prematures (73/219), 33,3 % ont beneficie d’une intubation en salle de naissance, quelle qu’en soit l’indication (mauvaise adaptation…

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Very preterm birth: who has access to antenatal corticosteroid therapy?

International audience; We describe the administration of antenatal corticosteroid therapy (ACT) for liveborn very preterm neonates in a population-based study. A total of 790 very preterm neonates (between 24 and 31 full weeks of gestation) were included in this regionally defined population of very preterm neonates in France. The main outcome measure was non-access to ACT. Data were analysed using logistic and polytomous models to control for neonatal and sociodemographic characteristics, mechanisms of very preterm birth and neonatal network organisation. As compared with level III, births in levels I-II maternity units were closely related to non-access to ACT (60.1% vs. 8.8%), but not t…

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