0000000000471157
AUTHOR
C Argano
Brain and kidney, victims of atrial microembolism in elderly hospitalized patients? Data from the REPOSI study
Abstract Background It is well known that atrial fibrillation (AF) and chronic kidney disease (CKD) are associated with a higher risk of stroke, and new evidence links AF to cognitive impairment, independently from an overt stroke (CI). Our aim was to investigate, assuming an underlying role of atrial microembolism, the impact of CI and CKD in elderly hospitalized patients with AF. Methods We retrospectively analyzed the data collected on elderly patients in 66 Italian hospitals, in the frame of the REPOSI project. We analyzed the clinical characteristics of patients with AF and different degrees of CI. Multivariate logistic analysis was used to explore the relationship between variables an…
Disability, and not diabetes, is a strong predictor of mortality in oldest old patients hospitalized with pneumonia
Abstract Background Pneumonia causes more deaths than any other infectious disease, especially in older patients with multiple chronic diseases. Recent studies identified a low functional status as prognostic factor for mortality in elderly patients with pneumonia while contrasting data are available about the role of diabetes. The aim of this study was to evaluate the in-hospital, 3-month and 1-year mortality in elderly subjects affected by pneumonia enrolled in the RePoSi register. Methods We retrospectively analyzed the data collected on hospitalized elderly patients in the frame of the REPOSI project. We analyzed the socio-demographic, laboratory and clinical characteristics of subjects…
Beta-Blocker Use in Older Hospitalized Patients Affected by Heart Failure and Chronic Obstructive Pulmonary Disease: An Italian Survey From the REPOSI Register
Beta (β)-blockers (BB) are useful in reducing morbidity and mortality in patients with heart failure (HF) and concomitant chronic obstructive pulmonary disease (COPD). Nevertheless, the use of BBs could induce bronchoconstriction due to β2-blockade. For this reason, both the ESC and GOLD guidelines strongly suggest the use of selective β1-BB in patients with HF and COPD. However, low adherence to guidelines was observed in multiple clinical settings. The aim of the study was to investigate the BBs use in older patients affected by HF and COPD, recorded in the REPOSI register. Of 942 patients affected by HF, 47.1% were treated with BBs. The use of BBs was significantly lower in patients with…
L’obesità fattore o co-fattore di rischio?
L’obesità rappresenta odiernamente uno dei problemi più rilevanti di salute pubblica al punto che l’Organizzazione Mondiale della Sanità (WHO) sostiene che essa debba essere considerata una vera e propria “epidemia globale” . L’obesità e le malattie ad essa correlate rappresentano nei paesi occidentali una delle cause principali di mortalità precoce e di morbilità. La prevalenza dell’obesità e del sovrappeso nei paesi industrializzati ed in quelli in via di sviluppo è stimata tra il 40% ed il 60%. Negli Stati Uniti d’America, i dati più recenti del National Health and Nutrition Survey (1999-2000) sottolineano come circa il 64.5% degli adulti (67.2% uomini e 61.9% donne) sono in sovrappeso e…