0000000000476435
AUTHOR
Jean-christophe Chauvet-gélinier
Biopsychosocial approach to caregiving burden: Why should we care about caregivers’ health?
There are 11 million family caregivers in France and some estimates indicate that there will be 17 million in 2020.Caregiving is a source of chronic stress that requires adaptation and coping strategies.Caregiving may benefit the health of a caregiver with a positive coping style and altruistic goals.However, the caregiver's burden is frequently associated with negative effects in terms of biopsychosocial imbalance and medical conditions, with frequent anxiety and depression.The management of the caregiving burden starts with the recognition of health professionals – caregivers may benefit from consultation-liaison psychiatry and multidisciplinary medico-social strategies, in addition to co…
Mast cells' involvement in inflammation pathways linked to depression: evidence in mastocytosis
International audience; Converging sources of evidence point to a role for inflammation in the development of depression, fatigue and cognitive dysfunction. More precisely, the tryptophan (TRP) catabolism is thought to play a major role in inflammation-induced depression. Mastocytosis is a rare disease in which chronic symptoms, including depression, are related to mast cell accumulation and activation. Our objectives were to study the correlations between neuropsychiatric features and the TRP catabolism pathway in mastocytosis in order to demonstrate mast cells' potential involvement in inflammation-induced depression. Fifty-four patients with mastocytosis and a mean age of 50.1 years were…