0000000000485432

AUTHOR

O. Andrea Wong

showing 3 related works from this author

Conformation and dynamics of the ligand shell of a water-soluble Au102 nanoparticle

2016

Inorganic nanoparticles, stabilized by a passivating layer of organic molecules, form a versatile class of nanostructured materials with potential applications in material chemistry, nanoscale physics, nanomedicine and structural biology. While the structure of the nanoparticle core is often known to atomic precision, gaining precise structural and dynamical information on the organic layer poses a major challenge. Here we report a full assignment of 1H and 13C NMR shifts to all ligands of a water-soluble, atomically precise, 102-atom gold nanoparticle stabilized by 44 para-mercaptobenzoic acid ligands in solution, by using a combination of multidimensional NMR methods, density functional t…

Magnetic Resonance SpectroscopyScienceGeneral Physics and AstronomyNanoparticleMetal NanoparticlesNanotechnologypara-mercaptobenzoic acid02 engineering and technologyMolecular Dynamics Simulation010402 general chemistry01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyArticleMolecular dynamicsta116Multidisciplinaryta114LigandligandsQGeneral ChemistryNuclear magnetic resonance spectroscopyliganditCarbon-13 NMR021001 nanoscience & nanotechnology0104 chemical sciencesStructural biologygold nanoparticlesNanomedicineDensity functional theoryGold0210 nano-technologyNature Communications
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Structural and Theoretical Basis for Ligand Exchange on Thiolate Monolayer Protected Gold Nanoclusters

2012

Ligand exchange reactions are widely used for imparting new functionality on or integrating nanoparticles into devices. Thiolate-for-thiolate ligand exchange in monolayer protected gold nanoclusters has been used for over a decade; however, a firm structural basis of this reaction has been lacking. Herein, we present the first single-crystal X-ray structure of a partially exchanged Au(102)(p-MBA)(40)(p-BBT)(4) (p-MBA = para-mercaptobenzoic acid, p-BBT = para-bromobenzene thiol) with p-BBT as the incoming ligand. The crystal structure shows that 2 of the 22 symmetry-unique p-MBA ligand sites are partially exchanged to p-BBT under the initial fast kinetics in a 5 min timescale exchange reacti…

Models Molecularchemistry.chemical_classificationta114LigandMetal NanoparticlesBridging ligandGeneral ChemistryAssociative substitutionCrystal structureCrystallography X-RayLigandsBiochemistryArticleCatalysisNanoclustersCrystallographyColloid and Surface ChemistrychemistryMonolayerSolventsThiolThermodynamicsDensity functional theoryGoldJournal of the American Chemical Society
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Dynamic Diglyme-Mediated Self-Assembly of Gold Nanoclusters

2015

We report the assembly of gold nanoclusters by the nonthiolate ligand diglyme into discrete and dynamic assemblies. To understand this surprising phenomenon, the assembly of Au20(SC2H4Ph)15-diglyme into Au20(SC2H4Ph)15-diglyme-Au20(SC2H4Ph)15 is explored in detail. The assembly is examined by high-angle annular dark field scanning transmission electron microscopy, size exclusion chromatography, mass spectrometry, IR spectroscopy, and calorimetry. We establish a dissociation constant for dimer to monomer conversion of 20.4 μM. Theoretical models validated by transient absorption spectroscopy predict a low-spin monomer and a high-spin dimer, with assembly enabled through weak diglyme oxygen-g…

DimerGeneral EngineeringGeneral Physics and AstronomyNanoparticleInfrared spectroscopyDiglymedynamic assemblyDark field microscopyNanoclusterschemistry.chemical_compoundCrystallographydiglymetransient absorption spectroscopychemistryChemical physicsScanning transmission electron microscopyGeneral Materials ScienceSpectroscopyta116gold nanoclustersACS Nano
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