0000000000496686

AUTHOR

Zhiyun Zhang

showing 2 related works from this author

Fluorescence Probes Exhibit Photoinduced Structural Planarization: Sensing <i>in vitro</i> and <i>in vivo</i> Microscopic Dyn…

2019

We demonstrate the construction of wavelength λ-ratiometric images that allow visualizing the distribution of microscopic dynamics within living cells and tissues by using the newly developed principle of fluorescence response. The bent-to-planar motion in the excited state of incorporated fluorescence probes leads to elongation of the π-delocalization, resulting in microviscosity-dependent but polarity-insensitive interplay between well-separated blue and red bands in emission spectra. This allows constructing the exceptionally contrasted images of cellular dynamics. Moreover, the application of probes with increased affinity towards biological membranes allowed detecting the differences i…

MicroviscosityWavelengthMembraneMaterials scienceExcited stateDynamics (mechanics)BiophysicsBiological membraneEmission spectrumFluorescenceSSRN Electronic Journal
researchProduct

Fluorescence Probes Exhibit Photoinduced Structural Planarization: Sensing In Vitro and In Vivo Microscopic Dynamics of Viscosity Free from Polarity …

2020

We demonstrate the construction of wavelength λ-ratiometric images that allow visualizing the distribution of microscopic dynamics within living cells and tissues by using the newly developed principle of fluorescence response. The bent-to-planar motion in the excited state of incorporated fluorescence probes leads to elongation of the π-delocalization, resulting in microviscosity-dependent but polarity-insensitive interplay between well-separated blue and red bands in emission spectra. This allows constructing the exceptionally contrasted images of cellular dynamics. Moreover, the application of probes with increased affinity toward biological membranes allowed detecting the differences in…

0301 basic medicineMaterials science010405 organic chemistryDynamics (mechanics)Biological membraneGeneral Medicine01 natural sciencesBiochemistryFluorescence0104 chemical sciencesMicroviscosity03 medical and health sciences030104 developmental biologyMembraneExcited stateMicroscopyBiophysicsMolecular MedicineEmission spectrumACS Chemical Biology
researchProduct