0000000000501417

AUTHOR

Simone Lumetti

showing 4 related works from this author

Correlation between Density and Resorption of Fresh-Frozen and Autogenous Bone Grafts

2014

Trial Design. This analysis compared the outcome of fresh-frozen versus autologous bone block grafts for horizontal ridge augmentation in patients with Cawood and Howell class IV atrophies.Methods. Seventeen patients received autologous grafts and 21 patients received fresh-frozen bone grafts. Patients underwent CT scans 1 week and 6 months after surgery for graft volume and density analysis.Results. Two autologous and 3 fresh-frozen grafts failed. Autologous and fresh-frozen grafts lost, respectively, 28% and 46% of their initial volume(P=0.028). It is noteworthy that less dense fresh-frozen blocks lost more volume than denser grafts (61% versus 16%).Conclusions. According to these 6-month…

AdultMalemedicine.medical_specialtyArticle SubjectBone densitylcsh:MedicineTransplantation AutologousGeneral Biochemistry Genetics and Molecular BiologyBone resorptionYoung AdultBone DensityAlveolar ProcessmedicineFrozen SectionsHumansIn patientBone ResorptionAutogenous bonedensity and resorptionFrozen section procedureBone TransplantationGeneral Immunology and Microbiologybusiness.industryAlveolar processlcsh:RGeneral MedicineMiddle Agedfresh-frozen bone graftsAUTOGENOUS BONEResorptionSurgerymedicine.anatomical_structureClinical StudyFresh frozenFemalebusinessBioMed Research International
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The Effect of Age, Gender, and Insertion Site on Marginal Bone Loss around Endosseous Implants: Results from a 3-Year Trial with Premium Implant Syst…

2014

Objectives.The goal of this study was to evaluate bone changes around endosseous implants in partially edentulous patients.Materials and Methods.A total of 632 two-stage implants were placed in 252 patients. The implants had straight emergence profile, ZirTi surface, 3.3 to 5 mm diameter, and 8.5 to 13 mm length. Bone levels were assessed on orthopantomography immediately after surgery and after 36 months and marginal bone loss (MBL) was calculated from their difference.Results.Cumulative survival rate was 98.73%. Overall MBL was 0.8 mm ± 0.03 (mean ± SEM). Higher MBL was observed around implants in the maxilla than in the mandible (P<0.007). A relation between implant diameter and MBL (…

MaleArticle SubjectRadiographyAlveolar Bone Losslcsh:MedicineDentistryInsertion sitechemical and pharmacologic phenomenaComorbidityGeneral Biochemistry Genetics and Molecular BiologyAge DistributionDental Implants Single-ToothPostoperative ComplicationsOlder patientsRisk FactorsMedicineDental Implantation Endosseous EndodonticHumansEndosseous implantsDental Restoration FailureSex DistributionOrthodonticsGeneral Immunology and Microbiologybusiness.industryIncidence (epidemiology)IncidenceJaw Edentulous Partiallylcsh:RMandibleGeneral MedicineDental Marginal AdaptationMiddle Agedbacterial infections and mycosesCausalityRadiographyTreatment OutcomeItalyMaxillaClinical StudyFemaleImplantbusinessBioMed Research International
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Stanozolol promotes osteogenic gene expression and apposition of bone mineral in vitro

2018

Abstract Stanozolol (ST) is a synthetic androgen with high anabolic potential. Although it is known that androgens play a positive role in bone metabolism, ST action on bone cells has not been sufficiently tested to support its clinical use for bone augmentation procedures. Objective: This study aimed to assess the effects of ST on osteogenic activity and gene expression in SaOS-2 cells. Material and Methods: SaOS-2 deposition of mineralizing matrix in response to increasing doses of ST (0-1000 nM) was evaluated through Alizarin Red S and Calcein Green staining techniques at 6, 12 and 24 days. Gene expression of runt-related transcription factor 2 (RUNX2), vitamin D receptor (VDR), osteopon…

0301 basic medicineTime FactorsBone matrixCore Binding Factor Alpha 1 SubunitReal-Time Polymerase Chain ReactionCalcitriol receptorBone remodelingCalcificationAndrology03 medical and health sciencesAnabolic AgentsCalcification PhysiologicOsteogenesisCell Line TumorBone cellHumansOsteonectinOsteopontinGeneral DentistryBone mineralAnalysis of VarianceOsteoblastsbiologyChemistryReproducibility of Resultslcsh:RK1-715RUNX2Apposition030104 developmental biologylcsh:DentistryLinear Modelsbiology.proteinAndrogensReceptors CalcitriolOriginal ArticleOsteopontinGene expressionOsteonectinStanozolol
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Stanozolol promotes osteogenic gene expression and apposition of bone mineral in vitro

2018

Abstract Stanozolol (ST) is a synthetic androgen with high anabolic potential. Although it is known that androgens play a positive role in bone metabolism, ST action on bone cells has not been sufficiently tested to support its clinical use for bone augmentation procedures. Objective: This study aimed to assess the effects of ST on osteogenic activity and gene expression in SaOS-2 cells. Material and Methods: SaOS-2 deposition of mineralizing matrix in response to increasing doses of ST (0-1000 nM) was evaluated through Alizarin Red S and Calcein Green staining techniques at 6, 12 and 24 days. Gene expression of runt-related transcription factor 2 (RUNX2), vitamin D receptor (VDR), osteopon…

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