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RESEARCH PRODUCT

Correlation between Density and Resorption of Fresh-Frozen and Autogenous Bone Grafts

G. GhiacciGuido Maria MacalusoSimone LumettiClaudio MarchettiUgo ConsoloCarlo GalliAndrea ToffoliMauro BonaniniAttilio Carlo SalgarelliEdoardo Manfredi

subject

AdultMalemedicine.medical_specialtyArticle SubjectBone densitylcsh:MedicineTransplantation AutologousGeneral Biochemistry Genetics and Molecular BiologyBone resorptionYoung AdultBone DensityAlveolar ProcessmedicineFrozen SectionsHumansIn patientBone ResorptionAutogenous bonedensity and resorptionFrozen section procedureBone TransplantationGeneral Immunology and Microbiologybusiness.industryAlveolar processlcsh:RGeneral MedicineMiddle Agedfresh-frozen bone graftsAUTOGENOUS BONEResorptionSurgerymedicine.anatomical_structureClinical StudyFresh frozenFemalebusiness

description

Trial Design. This analysis compared the outcome of fresh-frozen versus autologous bone block grafts for horizontal ridge augmentation in patients with Cawood and Howell class IV atrophies.Methods. Seventeen patients received autologous grafts and 21 patients received fresh-frozen bone grafts. Patients underwent CT scans 1 week and 6 months after surgery for graft volume and density analysis.Results. Two autologous and 3 fresh-frozen grafts failed. Autologous and fresh-frozen grafts lost, respectively, 28% and 46% of their initial volume(P=0.028). It is noteworthy that less dense fresh-frozen blocks lost more volume than denser grafts (61% versus 16%).Conclusions. According to these 6-month results, only denser fresh-frozen bone graft may be an acceptable alternative to autologous bone for horizontal ridge augmentation. Further studies are needed to investigate its behaviour at longer time points.

yearjournalcountryeditionlanguage
2014-06-01BioMed Research International
https://doi.org/10.1155/2014/508328