Search for Standard Model Higgs Boson Production in Association with a W Boson at CDF

We present a search for the standard model Higgs boson production in association with a W boson in proton-antiproton collisions (pp̅ →W±H→ℓνbb̅ ) at a center of mass energy of 1.96 TeV. The search employs data collected with the CDF II detector which correspond to an integrated luminosity of approximately 2.7  fb-1. We recorded this data with two kinds of triggers. The first kind required high-pT charged leptons and the second required both missing transverse energy and jets. The search selects events consistent with a signature of a single lepton (e±/μ±), missing transverse energy, and two jets. Jets corresponding to bottom quarks are identified with a secondary vertex tagging method and a…

Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

Crohn Disease (CD) is a complex genetic disorder for which more than 140 genes have been identified using genome wide association studies (GWAS). However, the genetic architecture of the trait remains largely unknown. The recent development of machine learning (ML) approaches incited us to apply them to classify healthy and diseased people according to their genomic information. The Immunochip dataset containing 18,227 CD patients and 34,050 healthy controls enrolled and genotyped by the international Inflammatory Bowel Disease genetic consortium (IIBDGC) has been re-analyzed using a set of ML methods: penalized logistic regression (LR), gradient boosted trees (GBT) and artificial neural ne…

Ultra-Fast Flash Observatory for observation of early photons from gamma ray bursts

We describe the space project of Ultra-Fast Flash Observatory (UFFO) which will observe early optical photons from gamma-ray bursts (GRBs) with a sub-second optical response, for the first time. The UFFO will probe the early optical rise of GRBs, opening a completely new frontier in GRB and transient studies, using a fast response Slewing Mirror Telescope (SMT) that redirects optical path to telescope instead of slewing of telescopes or spacecraft. In our small UFFO-Pathfinder experiment, scheduled to launch aboard the Lomonosov satellite in 2012, we use a motorized mirror in our Slewing Mirror Telescope instrument to achieve less than one second optical response after X-ray trigger. We des…

The global cardiovascular risk transition: associations of four metabolic risk factors with national income, urbanization, and Western diet in 1980 and 2008

Background— It is commonly assumed that cardiovascular disease risk factors are associated with affluence and Westernization. We investigated the associations of body mass index (BMI), fasting plasma glucose, systolic blood pressure, and serum total cholesterol with national income, Western diet, and, for BMI, urbanization in 1980 and 2008. Methods and Results— Country-level risk factor estimates for 199 countries between 1980 and 2008 were from a previous systematic analysis of population-based data. We analyzed the associations between risk factors and per capita national income, a measure of Western diet, and, for BMI, the percentage of the population living in urban areas. In 1980, the…

Search for new physics inlepton+photon+Xevents with929  pb−1ofpp¯collisions ats=1.96  TeV

The authors present results of a search for anomalous production of events containing a charged lepton ({ell}, either e or {mu}) and a photon ({gamma}), both with high transverse momentum, accompanied by additional signatures, X, including missing transverse energy (E{sub T}) and additional leptons and photons. We use the same kinematic selection criteria as in a previous CDF search, but with a substantially larger data set, 305 pb{sup -1}, a p{bar p} collision energy of 1.96 TeV, and the upgraded CDF II detector. We find 42 {ell}{gamma}E{sub T} events versus a standard model expectation of 37.3 {+-} 5.4 events. The level of excess observed in Run I, 16 events with an expectation of 7.6 {+-…

The PHENIX Collaboration

Development of Motorized Slewing Mirror Stage for the UFFO Project

The Ultra-Fast Flash Observatory (UFFO) is a space observatory for optical follow-ups of gamma ray bursts (GRBs), aiming to explore the first 60 seconds of GRBs optical emission. UFFO is utilized to catch early optical emissions from GRBs within few sec after trigger using a Gimbal mirror which redirects the optical path rather than slewing entire spacecraft. We have developed a 15 cm two-axis Gimbal mirror stage for the UFFO-Pathfinder which is going to be on board the Lomonosov satellite which is to be launched in 2013. The stage is designed for fast and accurate motion with given budgets of 3 kg of mass and 3 Watt of power. By employing stepping motors, the slewing mirror can rotate fast…

Abstracts of the 6th FECS Conference 1998 Lectures.

International audience

Optimization of the JUNO liquid scintillator composition using a Daya Bay antineutrino detector

To maximize the light yield of the liquid scintillator (LS) for the Jiangmen Underground Neutrino Observatory (JUNO), a 20 t LS sample was produced in a pilot plant at Daya Bay. The optical properties of the new LS in various compositions were studied by replacing the gadolinium-loaded LS in one antineutrino detector. The concentrations of the fluor, PPO, and the wavelength shifter, bis-MSB, were increased in 12 steps from 0.5 g/L and <0.01 mg/L to 4 g/L and 13 mg/L, respectively. The numbers of total detected photoelectrons suggest that, with the optically purified solvent, the bis-MSB concentration does not need to be more than 4 mg/L. To bridge the one order of magnitude in the detect…

Measurement of Inclusive Jet Cross Sections inZ/γ*(→e+e−)+jetsProduction inpp¯Collisions ats=1.96   TeV

Inclusive jet cross sections in Z/{gamma}* events, with Z/{gamma}* decaying into an electron-positron pair, are measured as a function of jet transverse momentum and jet multiplicity in p{bar p} collisions at {radical}s - 1.96 TeV with the upgraded Collider Detector at Fermilab in Run II, based on an integrated luminosity of 1.7 fb{sup -1}. The measurements cover the rapidity region |y{sup jet}| 30 GeV/c. Next-to-leading order perturbative QCD predictions are in good agreement with the measured cross sections.

The Status of the Ultra Fast Flash Observatory - Pathfinder

On behalf of the UFFO Collaboration; International audience; The Ultra Fast Flash Observatory (UFFO) is a project to study early optical emissions from Gamma Ray Bursts (GRBs). The primary scientific goal of UFFO is to see if GRBs can be calibrated with their rising times, so that they could be used as new standard candles. In order to minimize delay in optical follow-up measurements, which is now about 100 sec after trigger from the Swift experiment, we rotate a mirror to redirect light path so that optical measurement can be performed within a second after the trigger. We have developed a pathfinder mission, UFFO-pathfinder to launch on board the Lomonosov satellite in 2012. In this talk,…

Strong Evidence forZZProduction inpp¯Collisions ats=1.96  TeV

We report the first measurement of the cross section for Z boson pair production at a hadron collider. This result is based on a data sample corresponding to 1.9 fb{sup -1} of integrated luminosity from p{bar p} collisions at {radical}s = 1.96 TeV collected with the CDF II detector at the Fermilab Tevatron. In the {ell}{ell}{ell}{prime}{ell}{prime} channel, we observe three ZZ candidates with an expected background of 0.096{sub -0.063}{sup +0.092} events. In the {ell}{ell}{nu}{nu} channel, we use a leading-order calculation of the relative ZZ and WW event probabilities to discriminate between signal and background. In the combination of {ell}{ell}{ell}{prime}{ell}{prime} and {ell}{ell}{nu}{…

Measurement of thepp¯→tt¯production cross section and the top quark mass ats=1.96  TeVin the all-hadronic decay mode

We report the measurements of the t{bar t} production cross section and of the top quark mass using 1.02 fb{sup -1} of p{bar p} data collected with the CDF II detector at the Fermilab Tevatron. We select events with six or more jets on which a number of kinematical requirements are imposed by means of a neural network algorithm. At least one of these jets must be identified as initiated by a b-quark candidate by the reconstruction of a secondary vertex. The cross section is measured to be {sigma}{sub t{bar t}} = 8.3 {+-} 1.0(stat. ){sup +2.0}{sub -1.5}(syst.) {+-} 0.5(lumi.) pb, which is consistent with the standard model prediction. The top quark mass of 174.0 {+-} 2.2(stat.){+-}4.8(syst.)…

Ultra-Fast Flash Observatory: Fast Response Space Missions for Early Time Phase of Gamma Ray Bursts

One of the unexplored domains in the study of gamma-ray bursts (GRBs) is the early time phase of the optical light curve. We have proposed Ultra-Fast Flash Observatory (UFFO) to address this question through extraordinary opportunities presented by a series of small space missions. The UFFO is equipped with a fast-response Slewing Mirror Telescope that uses a rapidly moving mirror or mirror array to redirect the optical beam rather than slewing the entire spacecraft or telescope to aim the optical instrument at the GRB position. The UFFO will probe the early optical rise of GRBs with sub-second response, for the first time, opening a completely new frontier in GRB and transient studies. Its…

Diagnostic accuracy of non-invasive tests for advanced fibrosis in patients with NAFLD : an individual patient data meta-analysis

ObjectiveLiver biopsy is still needed for fibrosis staging in many patients with non-alcoholic fatty liver disease. The aims of this study were to evaluate the individual diagnostic performance of liver stiffness measurement by vibration controlled transient elastography (LSM-VCTE), Fibrosis-4 Index (FIB-4) and NAFLD (non-alcoholic fatty liver disease) Fibrosis Score (NFS) and to derive diagnostic strategies that could reduce the need for liver biopsies.DesignIndividual patient data meta-analysis of studies evaluating LSM-VCTE against liver histology was conducted. FIB-4 and NFS were computed where possible. Sensitivity, specificity and area under the receiver operating curve (AUROC) were c…

Calibration and Simulation of the GRB trigger detector of the Ultra Fast Flash Observatory

The UFFO (Ultra-Fast Flash Observatory) is a GRB detector on board the Lomonosov satellite, to be launched in 2013. The GRB trigger is provided by an X-ray detector, called UBAT (UFFO Burst Alarm & Trigger Telescope), which detects X-rays from the GRB and then triggers to determine the direction of the GRB and then alerts the Slewing Mirror Telescope (SMT) to turn in the direction of the GRB and record the optical photon fluxes. This report details the calibration of the two components: the MAPMTs and the YSO crystals and simulations of the UBAT. The results shows that this design can observe a GRB within a field of view of ±35° and can trigger in a time scale as short as 0.2 – 1.0 s af…

TH-302 + Gemcitabine (G + T) vs Gemcitabine (G) in Patients with Previously Untreated advanced Pancreatic Cancer (PAC)

ABSTRACT Background TH-302 is a hypoxia targeted prodrug with a hypoxia-triggered 2-nitroimidazole component designed to release the DNA alkylator, bromo-isophosphoramide mustard (Br-IPM), when reduced in severe hypoxia. A randomized Phase 2B study (NCT01144455) was conducted to assess the benefit of G + T to standard dose G as first-line therapy of PAC. Materials and methods An open-label multi-center study of two dose levels of TH-302 (240 mg/m2 or 340 mg/m2) in combination with G versus G alone (randomized 1:1:1). G (1000 mg/m2) and T were administered IV over 30-60 minutes on Days 1, 8 and 15 of a 28-day cycle. Patients on the G could crossover after progression and be randomized to a G…

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

Observation of Orbitally Excited Bs Mesons

We report the first observation of two narrow resonances consistent with states of orbitally excited (L=1) B_s mesons using 1 fb^{-1} of ppbar collisions at sqrt{s} = 1.96 TeV collected with the CDF II detector at the Fermilab Tevatron. We use two-body decays into K^- and B^+ mesons reconstructed as B^+ \to J/\psi K^+, J/\psi \to \mu^+ \mu^- or B^+ \to \bar{D}^0 \pi^+, \bar{D}^0 \to K^+ \pi^-. We deduce the masses of the two states to be m(B_{s1}) = 5829.4 +- 0.7 MeV/c^2 and m(B_{s2}^*) = 5839.7 +- 0.7 MeV/c^2.

In-Flight Calibrations of UFFO-Pathfinder

The Ultra-Fast Flash Observatory (UFFO), which will be launched onboard the Lomonosov spacecraft, contains two crucial instruments: UFFO Burst Alert & Trigger Telescope (UBAT) for detection and localization of Gamma-Ray Bursts (GRBs) and the fast-response Slewing Mirror Telescope (SMT) designed for the observation of the prompt optical/UV counterparts. Here we discuss the in-space calibrations of the UBAT detector and SMT telescope. After the launch, the observations of the standard X-ray sources such as pulsar in Crab nebula will provide data for necessary calibrations of UBAT. Several standard stars will be used for the photometric calibration of SMT. The celestial X-ray sources, e.g.…

Design and implementation of electronics and data acquisition system for Ultra-Fast Flash Observatory

The Ultra-Fast Flash Observatory (UFFO) Pathfinder for Gamma-Ray Bursts (GRBs) consists of two telescopes. The UFFO Burst Alert & Trigger Telescope (UBAT) handles the detection and localization of GRBs, and the Slewing Mirror Telescope (SMT) conducts the measurement of the UV/optical afterglow. UBAT is equipped with an X-ray detector, analog and digital signal readout electronics that detects X-rays from GRBs and determines the location. SMT is equipped with a stepping motor and the associated electronics to rotate the slewing mirror targeting the GRBs identified by UBAT. First the slewing mirror points to a GRB, then SMT obtains the optical image of the GRB using the intensified CCD an…

Search for signatures of magnetically-induced alignment in the arrival directions measured by the Pierre Auger Observatory

We present the results of an analysis of data recorded at the Pierre Auger Observatory in which we search for groups of directionally-aligned events (or ‘multiplets’) which exhibit a correlation between arrival direc- tion and the inverse of the energy. These signatures are expected from sets of events coming from the same source after having been deflected by intervening coherent magnetic fields. The observation of several events from the same source would open the possibility to accurately reconstruct the position of the source and also measure the integral of the component of the magnetic field orthogonal to the trajectory of the cos- mic rays. We describe the largest multiplets found an…

Limits on anomalous triple gauge couplings inpp¯collisions ats=1.96  TeV

We present a search for anomalous triple gauge couplings (ATGC) in WW and WZ boson production. The boson pairs are produced in p (p) over bar collisions at root s = 1.96 TeV, and the data sample corresponds to 350 pb(-1) of integrated luminosity collected with the CDF II detector at the Fermilab Tevatron. In this search one W decays to leptons, and the other boson (W or Z) decays hadronically. Combining with a previously published CDF measurement of W gamma boson production yields ATGC limits of -0.18 <lambda < 0.17 and -0.46 <Delta kappa < 0.39 at the 95% confidence level, using a cutoff scale Lambda=1.5 TeV.

AKI - human studies

Search for Maximal Flavor Violating Scalars in Same-Charge Lepton Pairs inpp¯Collisions ats=1.96  TeV

Models of maximal flavor violation (MxFV) in elementary particle physics may contain at least one new scalar SU(2) doublet field {phi}{sub FV}=({eta}{sup 0},{eta}{sup +}) that couples the first and third generation quarks (q{sub 1}, q{sub 3}) via a Lagrangian term L{sub FV}={xi}{sub 13}{phi}{sub FV}q{sub 1}q{sub 3}. These models have a distinctive signature of same-charge top-quark pairs and evade flavor-changing limits from meson mixing measurements. Data corresponding to 2 fb{sup -1} collected by the Collider Dectector at Fermilab II detector in pp collisions at {radical}(s)=1.96 TeV are analyzed for evidence of the MxFV signature. For a neutral scalar {eta}{sup 0} with m{sub {eta}{sup 0}…

Search for the Higgs Boson in Events with Missing Transverse Energy andbQuark Jets Produced inpp¯Collisions ats=1.96  TeV

We search for the standard model Higgs boson produced in association with an electroweak vector boson in events with no identified charged leptons, large imbalance in transverse momentum, and two jets where at least one contains a secondary vertex consistent with the decay of b hadrons. We use {approx}1 fb{sup -1} integrated luminosity of p{bar p} collisions at {radical}s = 1.96 TeV recorded by the CDF II experiment at the Tevatron. We find 268 (16) single (double) b-tagged candidate events, where 248 {+-} 43 (14.4 {+-} 2.7) are expected from standard model background processes. We place 95% confidence level upper limits on the Higgs boson production cross section for several Higgs boson ma…

Cold-nuclear-matter effects on heavy-quark production at forward and backward rapidity in d + Au collisions at √sNN = 200  GeV.

The PHENIX experiment has measured open heavy-flavor production via semileptonic decay over the transverse momentum range 1p(T)6  GeV/c at forward and backward rapidity (1.4|y|2.0) in d+Au and p + p collisions at √sNN = 200  GeV. In central d+Au collisions, relative to the yield in p + p collisions scaled by the number of binary nucleon-nucleon collisions, a suppression is observed at forward rapidity (in the d-going direction) and an enhancement at backward rapidity (in the Au-going direction). Predictions using nuclear-modified-parton-distribution functions, even with additional nuclear-p(T) broadening, cannot simultaneously reproduce the data at both rapidity ranges, which implies that t…

Search for a common baryon source in high-multiplicity pp collisions at the LHC

Physics letters / B B811, 135849 (2020). doi:10.1016/j.physletb.2020.135849

The readout system and the trigger algorithm implementation for the UFFO Pathfinder

Since the launch of the SWIFT, Gamma-Ray Bursts (GRBs) science has been much progressed. Especially supporting many measurements of GRB events and sharing them with other telescopes by the Gamma-ray Coordinate Network (GCN) have resulted the richness of GRB events, however, only a few of GRB events have been measured within a minute after the gamma ray signal. This lack of sub-minute data limits the study for the characteristics of the UV-optical light curve of the short-hard type GRB and the fast-rising GRB. Therefore, we have developed the telescope named the Ultra-Fast Flash Observatory (UFFO) Pathfinder, to take the sub-minute data for the early photons from GRB. The UFFO Pathfinder has…

Correction to: Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study (Intensive Care Medicine, (2016), 42, 12, (1865-1876), 10.1007/s00134-016-4571-5)

The members of the LUNG SAFE Investigators and the ESICM Trials Group were provided in such a way that they could not be indexed as collaborators on PubMed. The publisher apologizes for this error.

Multimessenger search for sources of gravitational waves and high-energy neutrinos: Initial results for LIGO-Virgo and IceCube

Made available in DSpace on 2022-04-29T07:21:49Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-11-17 We report the results of a multimessenger search for coincident signals from the LIGO and Virgo gravitational-wave observatories and the partially completed IceCube high-energy neutrino detector, including periods of joint operation between 2007-2010. These include parts of the 2005-2007 run and the 2009-2010 run for LIGO-Virgo, and IceCube's observation periods with 22, 59 and 79 strings. We find no significant coincident events, and use the search results to derive upper limits on the rate of joint sources for a range of source emission parameters. For the optimistic assumption of …

Search for intermediate mass black hole binaries in the first and second observing runs of the Advanced LIGO and Virgo network

Gravitational wave astronomy has been firmly established with the detection of gravitational waves from the merger of ten stellar mass binary black holes and a neutron star binary. This paper reports on the all-sky search for gravitational waves from intermediate mass black hole binaries in the first and second observing runs of the Advanced LIGO and Virgo network. The search uses three independent algorithms: two based on matched filtering of the data with waveform templates of gravitational wave signals from compact binaries, and a third, model-independent algorithm that employs no signal model for the incoming signal. No intermediate mass black hole binary event was detected in this sear…

Dielectron production in proton-proton and proton-lead collisions at √sNN=5.02TeV

The first measurements of dielectron production at midrapidity (|ηe| &lt; 0.8) in proton–proton and proton–lead collisions at √sNN = 5.02 TeV at the LHC are presented. The dielectron cross section is measured with the ALICE detector as a function of the invariant mass mee and the pair transverse momentum pT, ee in the ranges mee &lt; 3.5 GeV/c2 and pT, ee &lt; 8 GeV/c, in both collision systems. In proton–proton collisions, the charm and beauty cross sections are determined at midrapidity from a fit to the data with two different event generators. This complements the existing dielectron measurements performed at √s = 7 and 13 TeV. The slope of the √s dependence of the three measurements is…

Measurement of theΛb0Lifetime inΛb0→Λc+π−Decays inpp¯Collisions ats=1.96  TeV

We thank the Fermilab staff and the technical staffs of the participating institutions for their vital contributions. This work was supported by the U.S. Department of Energy and National Science Foundation; the Italian Istituto Nazionale di Fisica Nucleare; the Ministry of Education, Culture, Sports, Science and Technology of Japan; the Natural Sciences and Engineering Research Council of Canada; the National Science Council of the Republic of China; the Swiss National Science Foundation; the A.P. Sloan Foundation; the Bundesministerium fur Bildung und Forschung, Germany; the World Class University Program, the National Research Foundation of Korea; the Science and Technology Facilities Co…

Observation and Mass Measurement of the BaryonΞb−

We report the observation and measurement of the mass of the bottom, strange baryon $\Xi^-_b$ through the decay chain $\Xi^-_b \to J/\psi \Xi^-$, where $J/\psi \to \mu^+ \mu^-$, $\Xi^- \to \Lambda \pi^-$, and $\Lambda \to p \pi^-$. Evidence for observation is based on a signal whose probability of arising from the estimated background is 6.6 x 10^{-15}, or 7.7 Gaussian standard deviations. The $\Xi^-_b$ mass is measured to be $5792.9\pm 2.5$ (stat.) $\pm 1.7$ (syst.) MeV/$c^2$.

Design, Construction and Performance of the Detector for UFFO Burst Alert &amp; Trigger Telescope

One of the key aspects of the upcoming Ultra-Fast Flash Observatory (UFFO) pathfinder for Gamma Ray Bursts (GRBs) identification is the UFFO Burst Alert & Trigger Telescope (UBAT). The scientific propose of UBAT is to detect and locate as fast as possible the GRBs in the sky. This is achieved by using a coded mask aperture camera scheme with a wide field of view (FOV) and selecting a X-ray detector of high quantum efficiency and large detection area. This X-ray detector of high quantum efficiency and large detection area is called the UBAT detector. The UBAT detector consists of 48 × 48 Yttrium Oxyorthosilicate (YSO) scintillator crystal arrays and Multi Anode Photomultiplier Tubes (MAPMTs)…

Readout of the UFFO Slewing Mirror Telescope to detect UV/optical photons from Gamma-Ray Bursts

The Slewing Mirror Telescope (SMT) was proposed for rapid response to prompt UV/optical photons from Gamma-Ray Bursts (GRBs). The SMT is a key component of the Ultra-Fast Flash Observatory (UFFO)-pathfinder, which will be launched aboard the Lomonosov spacecraft at the end of 2013. The SMT utilizes a motorized mirror that slews rapidly forward to its target within a second after triggering by an X-ray coded mask camera, which makes unnecessary a reorientation of the entire spacecraft. Subsequent measurement of the UV/optical is accomplished by a 10 cm aperture Ritchey-Chretien telescope and the focal plane detector of Intensified Charge-Coupled Device (ICCD). The ICCD is sensitive to UV/opt…

Search for third generation vector leptoquarks inpp¯collisions ats=1.96  TeV

We search for a third generation vector leptoquark (VLQ3) that decays to a b quark and tau lepton using the CDF II detector and 320pb-1 of integrated luminosity from the Fermilab Tevatron. Observing a number of events in agreement with standard model expectations, we obtain, assuming Yang-Mills (minimal) couplings, the most stringent upper limit on the VLQ3 pair production cross section of 344 fb (493 fb) and lower limit on the VLQ3 mass of 317GeV/c2 (251GeV/c2) at 95% C.L. © 2008 The American Physical Society.

Inclusive Search for Standard Model Higgs Boson Production in the WW Decay Channel using the CDF II Detector

We present a search for standard model (SM) Higgs boson production using p (p) over bar collision data at root s = 1. 96 TeV, collected with the CDF II detector and corresponding to an integrated luminosity of 4. 8 fb(-1). We search for Higgs bosons produced in all processes with a significant production rate and decaying to two W bosons. We find no evidence for SM Higgs boson production and place upper limits at the 95% confidence level on the SM production cross section (sigma(H)) for values of the Higgs boson mass (m(H)) in the range from 110 to 200 GeV. These limits are the most stringent for m(H) > 130 GeV and are 1.29 above the predicted value of sigma(H) for m(H) 165 GeV.

Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study

Purpose: To evaluate patients with resolved versus confirmed ARDS, identify subgroups with substantial mortality risk, and to determine the utility of day 2 ARDS reclassification. Methods: Our primary objective, in this secondary LUNG SAFE analysis, was to compare outcome in patients with resolved versus confirmed ARDS after 24 h. Secondary objectives included identifying factors associated with ARDS persistence and mortality, and the utility of day 2 ARDS reclassification. Results: Of 2377 patients fulfilling the ARDS definition on the first day of ARDS (day 1) and receiving invasive mechanical ventilation, 503 (24%) no longer fulfilled the ARDS definition the next day, 52% of whom initial…

A study of the effect of molecular and aerosol conditions in the atmosphere on air fluorescence measurements at the Pierre Auger Observatory

The air fluorescence detector of the Pierre Auger Observatory is designed to perforin calorimetric measurements of extensive air showers created by Cosmic rays of above 10(18) eV. To correct these measurements for the effects introduced by atmospheric fluctuations, the Observatory contains a group Of monitoring instruments to record atmospheric conditions across the detector site, ail area exceeding 3000 km(2). The atmospheric data are used extensively in the reconstruction of air showers, and are particularly important for the correct determination of shower energies and the depths of shower maxima. This paper contains a summary of the molecular and aerosol conditions measured at the Pierr…

Male and female fertility preservation

Search for First Harmonic Modulation in the Right Ascension Distribution of Cosmic Rays Detected at the Pierre Auger Observatory

We present the results of searches for dipolar-type anisotropies in different energy ranges above 2.5 × 1017 eV with the surface detector array of the Pierre Auger Observatory, reporting on both the phase and the amplitude measurements of the first harmonic modulation in the right-ascension distribution. Upper limits on the amplitudes are obtained, which provide the most stringent bounds at present, being below 2% at 99% C.L. for EeV energies. We also compare our results to those of previous experiments as well as with some theoretical expectations.

Search for standard model Higgs bosons produced in association with W bosons.

We report on the results of a search for standard model Higgs bosons produced in association with W bosons from p-pbar collisions at root s = 1.96 TeV. The search uses a data sample corresponding to approximately 1 fb-1 of integrated luminosity. Events consistent with the W to l-nu and H to b-bbar signature are selected by triggering on a high-pT electron or muon candidate and tagging one or two of the jet candidates as having originated from b quarks. A neural network filter rejects a fraction of tagged charm and light flavor jets, increasing the b-jet purity in the sample and thereby reducing the background to Higgs boson production. We observe no excess l-nu-b-bbar production beyond the …

Development of Slewing Mirror Telescope Optical System for the UFFO-pathfinder

The Slewing Mirror Telescope (SMT) is the UV/optical telescope of UFFO-pathfinder. The SMT optical system is a Ritchey-Chretien (RC) telescope of 100 mm diameter pointed by means of a gimbal-mounted flat mirror in front of the telescope. The RC telescope has a 17 × 17arcmin2 in Field of View and 4.3 arcsec resolution (full width half maximum of the point spread function) The beam-steering mirror enables the SMT to access a 35 × 35degree region and point and settle within 1 sec. All mirrors were fabricated to about 0.02 wavelengths RMS in wave front error (WFE) and 84.7% average reflectivity over 200 nm ~ 650 nm. The RC telescope was aligned to 0.05 wavelengths RMS in WFE (test wavelength 63…

ULTRA-FAST FLASH OBSERVATORY (UFFO) FOR OBSERVATION OF EARLY PHOTONS FROM GAMMA RAY BURSTS

I.H. Park, S. Ahmad, P. Barrillon, S. Brandt, C. Budtz-Jorgensen, A.J. Castro-Tirado, P. Chen, Y.J. Choi, P. Connell, S. Dagoret-Campagne, C. Eyles, B. Grossan, M.–H.A. Huang, A. Jung, S. Jeong, J.E. Kim, M.B. Kim, S.-W. Kim, Y.W. Kim, A.S. Krasnov, J. Lee, H. Lim, E.V. Linder, T.–C. Liu, N. Lund, K.W. Min, G.W. Na, J.W. Nam, M.I. Panasyuk, J. Ripa, V. Reglero, J.M. Rodrigo, G.F. Smoot, J.E. Suh, S. Svertilov, N. Vedenkin, M.–Z. Wang, I. Yashin Ewha Womans University, Seoul, Korea University of Paris-Sud 11, Orsay, France Technical University of Denmark, Copenhagen, Denmark Instituto de Astrofisica de Andalucia CSIC, Granada, Spain National Taiwan University, Taipei, Taiwan Korea Advanced I…

The slewing mirror telescope of the Ultra Fast Flash Observatory Pathfinder

The Slewing Mirror Telescope (SMT) is a key telescope of Ultra-Fast Flash Observatory (UFFO) space project to explore the first sub-minute or sub-seconds early photons from the Gamma Ray Bursts (GRBs) afterglows. As the realization of UFFO, 20kg of UFFO-Pathfinder (UFFO-P) is going to be on board the Russian Lomonosov satellite in November 2012 by Soyuz-2 rocket. Once the UFFO Burst Alert & Trigger Telescope (UBAT) detects the GRBs, Slewing mirror (SM) will slew to bring new GRB into the SMT’s field of view rather than slewing the entire spacecraft. SMT can give a UV/Optical counterpart position rather moderated 4arcsec accuracy. However it will provide a important understanding of the GRB …

Cross section measurements of high-p(T) dilepton final-state processes using a global fitting method

We present a new method for studying high-$p_T$ dilepton events ($e^{\pm}e^{\mp}$, $\mu^{\pm}\mu^{\mp}$, $e^{\pm}\mu^{\mp}$) and simultaneously extracting the production cross sections of $p\bar{p} \to t\bar{t}$, $p\bar{p} \to W^+W^-$, and $p\bar{p} \to \ztt$ at a center-of-mass energy of $\sqrt{s} = 1.96$ TeV. We perform a likelihood fit to the dilepton data in a parameter space defined by the missing transverse energy and the number of jets in the event. Our results, which use $360 {\rm pb^{-1}}$ of data recorded with the CDF II detector at the Fermilab Tevatron Collider, are $\sigma(t\bar{t}) = 8.5_{-2.2}^{+2.7}$ pb, $\sigma(W^+W^-) = 16.3^{+5.2}_{-4.4}$ pb, and $\sigma(\ztt) =291^{+50}_…

GW190412: Observation of a binary-black-hole coalescence with asymmetric masses

LIGO Scientific Collaboration and Virgo Collaboration: et al.

Simultaneous investigation of the T=1(Jπ=0+) and T=0(Jπ=9+) β decays in Br70

The $\beta$ decay of the odd-odd nucleus $^{70}$Br has been investigated with the BigRIPS and EURICA setups at the Radioactive Ion Beam Factory (RIBF) of the RIKEN Nishina Center. The $T=0$ ($J^{\pi}=9^+$) and $T=1$ ($J^{\pi}=0^+$) isomers have both been produced in in-flight fragmentation of $^{78}$Kr with ratios of 41.6(8)\% and 58.4(8)\%, respectively. A half-life of $t_{1/2}=2157^{+53}_{-49}$ ms has been measured for the $J^{\pi}=9^+$ isomer from $\gamma$-ray time decay analysis. Based on this result, we provide a new value of the half-life for the $J^{\pi}=0^+$ ground state of $^{70}$Br, $t_{1/2}=78.42\pm0.51$ ms, which is slightly more precise, and in excellent agreement, with the bes…

Overview of the JET results with the ITER-like wall

Following the completion in May 2011 of the shutdown for the installation of the beryllium wall and the tungsten divertor, the first set of JET campaigns have addressed the investigation of the retention properties and the development of operational scenarios with the new plasma-facing materials. The large reduction in the carbon content (more than a factor ten) led to a much lower Zeff (1.2-1.4) during L- and H-mode plasmas, and radiation during the burn-through phase of the plasma initiation with the consequence that breakdown failures are almost absent. Gas balance experiments have shown that the fuel retention rate with the new wall is substantially reduced with respect to the C wall. T…

First measurement of the W-boson mass in run II of the Tevatron.

7 pages, 4 figures.-- PACS nrs.: 14.70.Fm; 13.38.Be; 13.85.Qk.-- ISI Article Identifier: 000250140600014.-- ArXiv pre-print available at: http://arxiv.org/abs/0707.0085.-- et al.

Measurement of the cross section forW-boson production in association with jets inpp¯collisions ats=1.96  TeV

We present a measurement of the cross section for W-boson production in association with jets in p{bar p} collisions at {radical}s = 1.96 TeV. The analysis uses a data sample corresponding to an integrated luminosity of 320 pb{sup -1} collected with the CDF II detector. W bosons are identified in their electron decay channel and jets are reconstructed using a cone algorithm. For each W + {ge} n-jet sample (n = 1-4) we measure {sigma}(p{bar p} {yields} W + {ge} n-jet) x {Beta}(W {yields} e{nu}) with respect to the transverse energy E{sub T} of the nth-highest E{sub T} jet above 20 GeV, for a restricted W {yields} e{nu} decay phase space. The cross sections, corrected for all detector effects…

First Measurement of Boson Production in Association with a Single Charm Quark in Collisions at

The authors present the first measurement of the production cross section of a W boson with a single charm quark (c) in p{bar p} collisions at {radical}s = 1.96 TeV, using soft muon tagging of c jets. In a data sample of {approx} 1.8 fb{sup -1}, recorded with the CDF II detector at the Fermilab Tevatron, they select events with W + 1 or 2 jets. They use the charge correlation between the W and the muon from the semileptonic decay of a charm hadron to extract the We signal. They measure {sigma}{sub Wc} (p{sub Tc} > 20 GeV/c, |{eta}{sub c}| < 1.5) x BR(W {yields} {ell}{nu}) = 9.8 {+-} 3.2 pb, in agreement with theoretical expectations.

Design and implementation of the UFFO burst alert and trigger telescope

The Ultra Fast Flash Observatory pathfinder (UFFO-p) is a telescope system designed for the detection of the prompt optical/UV photons from Gamma-Ray Bursts (GRBs), and it will be launched onboard the Lomonosov spacecraft in 2012. The UFFO-p consists of two instruments: the UFFO Burst Alert and Trigger telescope (UBAT) for the detection and location of GRBs, and the Slewing Mirror Telescope (SMT) for measurement of the UV/optical afterglow. The UBAT isa coded-mask aperture X-ray camera with a wide field of view (FOV) of 1.8 sr. The detector module consists of the YSO(Yttrium Oxyorthosilicate) scintillator crystal array, a grid of 36 multi-anode photomultipliers (MAPMTs), and analog and digi…

LAB-STEM CELLS

Search for Gravitational Waves Associated with Gamma-Ray Bursts Detected by Fermi and Swift during the LIGO-Virgo Run O3a

Abbott, R., et al. (LIGO and VIRGO Collaboration)

Correlation of the highest-energy cosmic rays with nearby extragalactic objects.

Using data collected at the Pierre Auger Observatory during the past 3.7 years, we demonstrated a correlation between the arrival directions of cosmic rays with energy above ~ 6x10^{19} electron volts and the positions of active galactic nuclei (AGN) lying within ~ 75 megaparsecs. We rejected the hypothesis of an isotropic distribution of these cosmic rays with at least a 99% confidence level from a prescribed a priori test. The correlation we observed is compatible with the hypothesis that the highest energy particles originate from nearby extragalactic sources whose flux has not been substantially reduced by interaction with the cosmic background radiation. AGN or objects having a similar…

Observation of Exclusive Dijet Production at the Fermilab Tevatron p-pbar Collider

We present the first observation and cross section measurement of exclusive dijet production in pbar-p interactions, pbar + p --&gt; pbar + dijet + p. Using a data sample of 310 pb-1 collected by the Run II Collider Detector at Fermilab at sqrt{s}=1.96 TeV, exclusive cross sections for events with two jets of transverse energy ET &gt;= 10 GeV have been measured as a function of minimum ET(jet). The exclusive signal is extracted from fits to data distributions based on Monte Carlo simulations of expected dijet signal and background shapes. The simulated background distribution shapes are checked in a study of a largely independent data sample of 200 pb-1 of b-tagged jet events, where exclusi…

Inverted-conical light guide for crosstalk reduction in tightly-packed scintillator matrix and MAPMT assembly

Abstract In this paper we present the Inverted-Conical light guide designed for optical crosstalk reduction in the scintillator-MAPMT assemblies. The research was motivated by the 30% crosstalk observed in UFFO X-ray telescope , UBAT, during the preliminary calibration with MAPMTs of 64 2.88 × 2.88 mm2 pixels and identically gridded YSO crystal matrices. We began the study with the energy and crosstalk calibrations of the detector, then we constructed a GEANT4 simulation with the customized metallic film model as the MAPMT photocathode . The simulation reproduced more than 70% of the crosstalk and explained it as a consequence of the total reflection produced by the photocathode. The result…

Measurement of the Depth of Maximum of Extensive Air Showers above 10(18) eV

We describe the measurement of the depth of maximum, Xmax, of the longitudinal development of air showers induced by cosmic rays. Almost four thousand events above 10¹⁸ eV observed by the fluorescence detector of the Pierre Auger Observatory in coincidence with at least one surface detector station are selected for the analysis. The average shower maximum was found to evolve with energy at a rate of (106⁺³⁵₋₂₁) g/cm²/decade below 1018.24 ± 0.05 eV and (24 ± 3) g/cm²/decade above this energy. The measured shower-to-shower fluctuations decrease from about 55 to 26 g/cm². The interpretation of these results in terms of the cosmic ray mass composition is briefly discussed.

Search for chargino-neutralino production inpp¯collisions ats=1.96  TeVwith high-pTleptons

We present a search for the associated production of charginos and neutralinos in pp collisions at s=1.96TeV. The data were collected at the Collider Detector at Fermilab (CDF II) and correspond to integrated luminosities between 0.7 and 1.0fb-1. We look for final states with one high-pT electron or muon, and two additional leptons. Our results are consistent with the standard model expectations, and we set limits on the cross section as a function of the chargino mass in three different supersymmetric scenarios. For a specific minimal supersymmetric standard model scenario with no slepton mixing, we set a 95% C.L. limit at 151GeV/c2. © 2008 The American Physical Society.

Measurements of mixed harmonic cumulants in Pb–Pb collisions at sNN=5.02 TeV

Correlations between moments of different flow coefficients are measured in Pb–Pb collisions at sNN=5.02 TeV recorded with the ALICE detector. These new measurements are based on multiparticle mixed harmonic cumulants calculated using charged particles in the pseudorapidity region |η|&lt;0.8 with the transverse momentum range 0.2&lt;pT&lt;5.0 GeV/c. The centrality dependence of correlations between two flow coefficients as well as the correlations between three flow coefficients, both in terms of their second moments, are shown. In addition, a collection of mixed harmonic cumulants involving higher moments of v2 and v3 is measured for the first time, where the characteristic signature of ne…

Search for Gravitational-wave Signals Associated with Gamma-Ray Bursts during the Second Observing Run of Advanced LIGO and Advanced Virgo

We present the results of targeted searches for gravitational-wave transients associated with gamma-ray bursts during the second observing run of Advanced LIGO and Advanced Virgo, which took place from 2016 November to 2017 August. We have analyzed 98 gamma-ray bursts using an unmodeled search method that searches for generic transient gravitational waves and 42 with a modeled search method that targets compact-binary mergers as progenitors of short gamma-ray bursts. Both methods clearly detect the previously reported binary merger signal GW170817, with p-values of <9.38 10-6 (modeled) and 3.1 10-4 (unmodeled). We do not find any significant evidence for gravitational-wave signals associate…

Upper limit on the cosmic-ray photon flux above 1019 eV using the surface detector of the Pierre Auger Observatory

A method is developed to search for air showers initiated by photons using data recorded by the surface detector of the Auger Observatory. The approach is based on observables sensitive to the longitudinal shower development, the signal risetime and the curvature of the shower front. Applying this method to the data, upper limits on the flux of photons of 3.8 x 10-3, 2.5 x 10-3; and 2.2 x 10-3 km-2 sr-1 yr-1 above 1019 eV, 2 x 1019 eV; and 4 x 1019 eV are derived, with corresponding limits on the fraction of photons being 2.0%, 5.1%, and 31% (all limits at 95% c.l.). These photon limits disfavor certain exotic models of sources of cosmic rays. The results also show that the approach adopted…

Search for new particles leading toZ+jetsfinal states inpp¯collisions ats=1.96  TeV

We present the results of a search for new particles that lead to a Z boson plus jets in p{bar p} collisions at {radical}s = 1.96 TeV using the Collider Detector at Fermilab (CDF II). A data sample with a luminosity of 1.06 fb{sup -1} collected using Z boson decays to ee and {mu}{mu} is used. We describe a completely data-based method to predict the dominant background from standard-model Z+jet events. This method can be similarly applied to other analyses requiring background predictions in multi-jet environments, as shown when validating the method by predicting the background from W+jets in t{bar t} production. No significant excess above the background prediction is observed, and a limi…

Search for ultrahigh energy neutrinos in highly inclined events at the Pierre Auger Observatory

Erratum: Phys. Rev. D 85, 029902(E) (2012) [http://dx.doi.org/10.1103/PhysRevD.85.029902]

The effect of the geomagnetic field on cosmic ray energy estimates and large scale anisotropy searches on data from the Pierre Auger Observatory

We present a comprehensive study of the influence of the geomagnetic field on the energy estimation of extensive air showers with a zenith angle smaller than $60^\circ$, detected at the Pierre Auger Observatory. The geomagnetic field induces an azimuthal modulation of the estimated energy of cosmic rays up to the ~2% level at large zenith angles. We present a method to account for this modulation of the reconstructed energy. We analyse the effect of the modulation on large scale anisotropy searches in the arrival direction distributions of cosmic rays. At a given energy, the geomagnetic effect is shown to induce a pseudo-dipolar pattern at the percent level in the declination distribution t…

A next generation Ultra-Fast Flash Observatory (UFFO-100) for IR/optical observations of the rise phase of gamma-ray bursts

The Swift Gamma-ray Burst (GRB) observatory responds to GRB triggers with optical observations in ~ 100 s, but cannot respond faster than ~ 60 s. While some ground-based telescopes respond quickly, the number of sub-60 s detections remains small. In mid- to late-2013, the Ultra-Fast Flash Observatory-Pathfinder is to be launched on the Lomonosov spacecraft to investigate early optical GRB emission. This pathfinder mission is necessarily limited in sensitivity and event rate; here we discuss a next generation rapid-response space observatory. We list science topics motivating our instruments, those that require rapid optical-IR GRB response, including: A survey of GRB rise shapes/times, meas…

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

non presente

Cross-section-constrained top-quark mass measurement from dilepton events at the tevatron

We report the first top quark mass measurement that uses a cross section constraint to improve the mass determination. This measurement is made with a dilepton $t\bar{t}$ event sample collected with the CDF II detector. From a data sample corresponding to an integrated luminosity of 1.2 fb$^{-1}$, we measure a top quark mass of $\rm{170.7^{+4.2}_{-3.9}(stat)\pm2.6(syst)}$ $\rm{\pm2.4(theory) GeV/{\it{c}}^{2}}$. The measurement without the cross section constraint results in a top quark mass of $\rm{169.7^{+5.2}_{-4.9}(stat)\pm3.1(syst) GeV/{\it{c}}^{2}}$.

Search for doubly charged higgs bosons with lepton-rlavor-violating decays involving τ leptons

We search for pair production of doubly charged Higgs particles (H(+/-+/-)) followed by decays into electron-tau (e tau) and muon-tau (mu tau) pairs using data (350 pb(-1)) collected from (p) over barp collisions at root s = 1.96 TeV by the CDF II experiment. We search separately for cases where three or four final-state leptons are detected, and combine results for exclusive decays to left-handed e tau (mu tau) pairs. We set an H(+/-+/-) lower mass limit of 114(112) GeV/c(2) at the 95% confidence level. RI Ruiz, Alberto/E-4473-2011; Robson, Aidan/G-1087-2011; De Cecco, Sandro/B-1016-2012; Prokoshin, Fedor/E-2795-2012; Azzi, Patrizia/H-5404-2012

Slewing Mirror Telescope and the Data-Acquisition System for the UFFO-Pathfinder

The Ultra-Fast Flash Observatory (UFFO) aims to detect the earliest moment of Gamma-Ray Bursts (GRBs) which is not well known, resulting into the enhancement of GRB mechanism understanding. The pathfinder mission was proposed to be a scaled-down version of UFFO, and only contains the UFFO Burst Alert &amp; Trigger Telescope (UBAT) measuring the X-ray/gamma-ray with the wide-field of view and the Slewing Mirror Telescope (SMT) with a rapid-response for the UV/optical photons. Once the UBAT detects a GRB candidate with the position accuracy of 10 arcmin, the SMT steers the UV/optical photons from the candidate to the telescope by the fast rotatable mirror and provides the early UV/optical pho…

Design and Fabrication of Detector Module for UFFO Burst Alert & Trigger Telescope

The Ultra-Fast Flash Observatory (UFFO) pathfinder is a space mission devoted to the measurement of Gamma-Ray Bursts (GRBs), especially their early light curves which will give crucial information on the progenitor stars and central engines of the GRBs. It consists of two instruments: the UFFO Burst Alert & Trigger telescope (UBAT) for the detection of GRB locations and the Slewing Mirror Telescope (SMT) for the UV/optical afterglow observations, upon triggering by UBAT. The UBAT employs a coded-mask {\gamma}/X-ray camera with a wide field of view (FOV), and is comprised of three parts: a coded mask, a hopper, and a detector module (DM). The UBAT DM consists of a LYSO scintillator crystal a…

Sustained Late Branch Patency and Low Incidence of Persistent Type Ia Endoleaks Following Snorkel/chimney EVAR Shown in the Updated PERICLES Registry

THE UFFO SLEWING MIRROR TELESCOPE FOR EARLY OPTICAL OBSERVATION FROM GAMMA RAY BURSTS

While some space born observatories, such as SWIFT and FERMI, have been operating, early observation of optical after grow of GRBs is still remained as an unexplored region. The Ultra-Fast Flash Observatory (UFFO) project is a space observatory for optical follow-ups of GRBs, aiming to explore the first 60 seconds of GRBs optical emission. Using fast moving mirrors to redirect our optical path rather than slewing the entire spacecraft, UFFO is utilized to catch early optical emissions from GRB within 1 sec. We have developed the UFFO Pathfinder Telescope which is going to be on board of the Lomonosov satellite and launched in middle of 2012. We will discuss about scientific potentials of t…

Search for GW signals associated with GRBs

We present the results of targeted searches for gravitational-wave transients associated with gamma-ray bursts during the second observing run of Advanced LIGO and Advanced Virgo, which took place from 2016 November to 2017 August. We have analyzed 98 gamma-ray bursts using an unmodeled search method that searches for generic transient gravitational waves and 42 with a modeled search method that targets compact-binary mergers as progenitors of short gamma-ray bursts. Both methods clearly detect the previously reported binary merger signal GW170817, with p-values of <9.38x10^-6^ (modeled) and 3.1x10^-4^ (unmodeled). We do not find any significant evidence for gravitational-wave signals assoc…