0000000000523710

AUTHOR

Liberia Cusumano

showing 2 related works from this author

Benign myoclonic epilepsy in infancy: neuropsychological and behavioural outcome

2003

Benign myoclonic epilepsy in infancy (BMEI) is a rare syndrome of idiopathic generalized epilepsies with onset below 3 years of age. It has been reported that BMEI is associated with a good prognosis, however, recently some studies suggest less favourable neuropsychological outcome. We report a long-term follow-up of seven patients with BMEI. Seizure outcome and neuropsychological, cognitive, and behavioural evolution were discussed for each of them. At the end of follow-up, 86% of children showed neuropsychological and intellectual disorders: two children had mental retardation, three patients achieved a borderline IQ and one normal but low IQ. All but one displayed neuropsychological disa…

MalePediatricsmedicine.medical_specialtyDevelopmental DisabilitiesEpilepsies MyoclonicNeuropsychological TestsBorderline intellectual functioningCognitionDevelopmental NeurosciencemedicineRare syndromeHumansAge of OnsetPsychiatryChildNeuropsychological outcomeBenign myoclonic epilepsy in infancyNeuropsychologyLanguage impairmentBehavioural outcomeCognitionElectroencephalographyGeneral Medicinemedicine.diseaseFine motor skillOnset ageChild PreschoolPediatrics Perinatology and Child HealthMyoclonic epilepsyFemaleNeurology (clinical)Good prognosisPsychology
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Non-convulsive status epilepticus associated with tiagabine in a pediatric patient

2003

We report a 4-year-old patient who developed non-convulsive status epilepticus (NCSE) following tiagabine (TGB) as add-on treatment for refractory partial seizures. NCSE occurred while the patient received TGB 0.83mg/kg/day. In our case, the TGB reduction led to a significant improvement of electroclinical features. The mechanisms of this abnormal effect are not clear. GABA-ergic hyperfunction and/or multiplicity of interlinked brain GABA systems associated with individual specific sensitivity could play a critical role in the pathogenesis of NCSE. This is the first report of NCSE documented by electroencephalogram (EEG) in a child under 12 years of age on TGB treatment. © 2003 Elsevier Sci…

MaleTiagabinemedicine.medical_treatmentNipecotic AcidsStatus epilepticusNon-convulsive status epilepticuElectroencephalographyCentral nervous system diseaseEpilepsyStatus EpilepticusDevelopmental NeuroscienceRefractorymedicineHumansTiagabineEpilepsymedicine.diagnostic_testbusiness.industryElectroencephalographyGeneral Medicinemedicine.diseaseAnticonvulsantnervous systemEl NiñoChild PreschoolAnesthesiaPediatrics Perinatology and Child HealthAnticonvulsantsEpilepsies PartialNeurology (clinical)medicine.symptombusinessmedicine.drugBrain and Development
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