0000000000529601

AUTHOR

Linus Girdland-flink

showing 3 related works from this author

CoproID predicts the source of coprolites and paleofeces using microbiome composition and host DNA content

2020

Shotgun metagenomics applied to archaeological feces (paleofeces) can bring new insights into the composition and functions of human and animal gut microbiota from the past. However, paleofeces often undergo physical distortions in archaeological sediments, making their source species difficult to identify on the basis of fecal morphology or microscopic features alone. Here we present a reproducible and scalable pipeline using both host and microbial DNA to infer the host source of fecal material. We apply this pipeline to newly sequenced archaeological specimens and show that we are able to distinguish morphologically similar human and canine paleofeces, as well as non-fecal sediments, fro…

dogsArcheologyMicrobial DNAData Mining and Machine LearningCoprolitemicrobiomeendogenous DNAlcsh:MedicineMorphology (biology)Genomechemistry.chemical_compoundPaleofecesDog0601 history and archaeologyGutArqueologia Metodologia0303 health sciences060102 archaeologyGeneral NeuroscienceGeneral Medicine06 humanities and the artsGenomicsNextflowmachine learningnextflowgutGeneral Agricultural and Biological SciencesShotgun metagenomicsPaleofecesHumanpaleofecesBioinformaticsBiologyMicrobiologyGeneral Biochemistry Genetics and Molecular Biologydiversity03 medical and health sciencesEndogenous DNAMachine learningcoprolitedog molecular analysishumanMicrobiomeancient DNAgenome030304 developmental biology030306 microbiologyHost (biology)lcsh:RcultureAncient DNAarcheologychemistryEvolutionary biologyAnthropologyCoproliteMicrobiomedietDNAPeerJ
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Correction for Frantz et al., Ancient pigs reveal a near-complete genomic turnover following their introduction to Europe

2020

Significance Archaeological evidence indicates that domestic pigs arrived in Europe, alongside farmers from the Near East ∼8,500 y ago, yet mitochondrial genomes of modern European pigs are derived from European wild boars. To address this conundrum, we obtained mitochondrial and nuclear data from modern and ancient Near Eastern and European pigs. Our analyses indicate that, aside from a coat color gene, most Near Eastern ancestry in the genomes of European domestic pigs disappeared over 3,000 y as a result of interbreeding with local wild boars. This implies that pigs were not domesticated independently in Europe, yet the first 2,500 y of human-mediated selection applied by Near Eastern Ne…

Gene FlowMultidisciplinarySwineLibrary scienceSkin PigmentationBiological SciencesCorrectionsDNA MitochondrialDomesticationEuropeMiddle EastAnthropologyevolutionAnimalsNeolithicDNA AncientHistory AncientPhylogeny
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Ancient pigs reveal a near-complete genomic turnover following their introduction to Europe

2019

International audience; Archaeological evidence indicates that pig domestication had begun by ∼10,500 y before the present (BP) in the Near East, and mitochondrial DNA (mtDNA) suggests that pigs arrived in Europe alongside farmers ∼8,500 y BP. A few thousand years after the introduction of Near Eastern pigs into Europe, however, their characteristic mtDNA signature disappeared and was replaced by haplotypes associated with European wild boars. This turnover could be accounted for by substantial gene flow from local Euro-pean wild boars, although it is also possible that European wild boars were domesticated independently without any genetic contribution from the Near East. To test these hyp…

0301 basic medicineSwine[SHS.ANTHRO-BIO]Humanities and Social Sciences/Biological anthropologySkin Pigmentation[SHS]Humanities and Social SciencesGene flowDomesticationddc:590BREEDSDOMESTIC PIGS/dk/atira/pure/subjectarea/asjc/1000HISTORY0601 history and archaeologyNeolithicHistory AncientPhylogenyMultidisciplinary060102 archaeologyINTROGRESSIONEurope ; pigs ; domestication ; genomesWILD06 humanities and the artsArchaeological evidenceGene flowEuropeSPREADCoatMitochondrial DNAEvolutionZoology930Locus (genetics)BiologyAnimal Breeding and GenomicsDNA MitochondrialMiddle East03 medical and health sciencesAnimalsFokkerij en GenomicaDNA AncientGeneralDomesticationddc:930HaplotypeDNA900 Geschichte und Geografie::930 Geschichte des Altertums (bis ca. 499) Archäologie::930 Geschichte des Altertums bis ca. 499 ArchäologieLONGSIZE030104 developmental biologydomestication evolution gene flow NeolithicWIAS
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