0000000000536004

AUTHOR

Arianna Quintavalla

0000-0002-0993-6855

showing 2 related works from this author

A Liquid-Liquid Biphasic Homogeneous Organocatalytic Aldol Protocol Based on the Use of a Silica Gel Bound Multilayered Ionic Liquid Phase

2012

An innovative two stage liquid–liquid biphasic homogeneous protocol for the asymmetric organocatalytic aldol reaction is proposed, based on the use of the cis-ion-tagged proline 8 dissolved in the liquid film of a multilayered ionic liquid covalently bonded to silica gel 4. The resulting catalytically active material 9 is first soaked with cyclohexanone in the presence of water, resulting in a semi-transparent gel, then the aldehyde is added and the mixture stirred at RT. In the first stage, 4 acts as a catalyst reservoir that delivers 8 to the cyclohexanone phase allowing the reaction to take place homogeneously. In the second stage, cyclohexanone is removed under vacuum and the resulting …

ChemistrySilica gelOrganic ChemistryInorganic chemistrySettore CHIM/06 - Chimica OrganicaorganocatalysiHeterogeneous catalysisaldehydeCatalysisCatalysisionic liquidsInorganic Chemistrychemistry.chemical_compoundAldol reactionChemical engineeringHomogeneousPhase (matter)OrganocatalysisIonic liquidaldol reactionPhysical and Theoretical Chemistrybiphasic catalysiChemCatChem
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ChemInform Abstract: A Liquid-Liquid Biphasic Homogeneous Organocatalytic Aldol Protocol Based on the Use of a Silica Gel Bound Multilayered Ionic Li…

2012

Key feature of the title protocol is the use of a cis-ion-tagged proline dissolved in a liquid film on a multilayered ionic liquid covalently bound to silica. The resulting catalytically active material is soaked in cyclohexanone and water to form a semi-transparent gel which then reacts with the aldehyde.

chemistry.chemical_classificationchemistry.chemical_compoundchemistryChemical engineeringAldol reactionCovalent bondSilica gelOrganocatalysisPhase (matter)Ionic liquidCyclohexanoneGeneral MedicineAldehydeChemInform
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