0000000000536192

AUTHOR

A Weber

showing 7 related works from this author

Effect of Intraoperative High Positive End-Expiratory Pressure (PEEP) with Recruitment Maneuvers vs Low PEEP on Postoperative Pulmonary Complications…

2019

Importance: An intraoperative higher level of positive end-expiratory positive pressure (PEEP) with alveolar recruitment maneuvers improves respiratory function in obese patients undergoing surgery, but the effect on clinical outcomes is uncertain. Objective: To determine whether a higher level of PEEP with alveolar recruitment maneuvers decreases postoperative pulmonary complications in obese patients undergoing surgery compared with a lower level of PEEP. Design, Setting, and Participants: Randomized clinical trial of 2013 adults with body mass indices of 35 or greater and substantial risk for postoperative pulmonary complications who were undergoing noncardiac, nonneurological surgery un…

Lung DiseasesMalemedicine.medical_treatmentAtelectasisLung Disease01 natural sciencesBody Mass IndexHypoxemiaPositive-Pressure RespirationPostoperative Complications0302 clinical medicinePEEP postoperative complications obese patientsAnesthesiaRespiratory function030212 general & internal medicineTidal volumeGeneral MedicineMiddle AgedPleural Diseasesrespiratory systemAdult; Anesthesia General; Body Mass Index; Female; Humans; Lung Diseases; Male; Middle Aged; Obesity; Pleural Diseases; Positive-Pressure Respiration; Postoperative Complications; Pulmonary Atelectasis; Respiratory Insufficiency; Surgical Procedures Operative; Tidal Volume; Treatment Outcome; Intraoperative CareOperative3. Good healthTreatment OutcomePneumothoraxSurgical Procedures OperativeAnesthesiaFemalemedicine.symptomRespiratory Insufficiencypsychological phenomena and processesHumancirculatory and respiratory physiologyAdultPulmonary AtelectasisAnesthesia GeneralNO03 medical and health sciencesmental disordersTidal VolumemedicineHumansPleural DiseaseObesity0101 mathematicsGeneralPositive end-expiratory pressureMechanical ventilationSurgical ProceduresIntraoperative CarePulmonary Atelectasibusiness.industry010102 general mathematicsmedicine.diseaserespiratory tract diseasesRespiratory failurePostoperative Complicationbusiness
researchProduct

Linkage disequilibrium screening for multiple sclerosis implicates JAG1 and POU2AF1 as susceptibility genes in Europeans.

2006

By combining all the data available from the Genetic Analysis of Multiple sclerosis in EuropeanS (GAMES) project, we have been able to identify 17 microsatellite markers showing consistent evidence for apparent association. As might be expected five of these markers map within the Major Histocompatibility Complex (MHC) and are in LD with HLA-DRB1. Individual genotyping of the 12 non-MHC markers confirmed association for three of them — D11S1986, D19S552 and D20S894. Association mapping across the candidate genes implicated by these markers in 937 UK trio families revealed modestly associated haplotypes in JAG1 (p=0.019) on chromosome 20p12.2 and POU2AF1 (p=0.003) on chromosome 11q23.1.

Multiple sclerosisGenome screenLinkage disequilibriumMeta-analysiSettore MED/26 - NeurologiaJAG1POU2AF1
researchProduct

Measurement of the intrinsic electron neutrino component in the T2K neutrino beam with the ND280 detector

2014

The T2K experiment has reported the first observation of the appearance of electron neutrinos in a muon neutrino beam. The main and irreducible background to the appearance signal comes from the presence in the neutrino beam of a small intrinsic component of electron neutrinos originating from muon and kaon decays. In T2K, this component is expected to represent 1.2% of the total neutrino flux. A measurement of this component using the near detector (ND280), located 280 m from the target, is presented. The charged current interactions of electron neutrinos are selected by combining the particle identification capabilities of both the time projection chambers and electromagnetic calorimeters…

Nuclear and High Energy PhysicsParticle physicsPhysics::Instrumentation and DetectorsSolar neutrinoAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciences01 natural sciences7. Clean energyHigh Energy Physics - ExperimentNuclear physicsHigh Energy Physics - Experiment (hep-ex)0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]010306 general physicsNeutrino oscillationPhysics010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyT2K experimentFísicaSolar neutrino problem3. Good healthCosmic neutrino backgroundNeutrino detectorMeasurements of neutrino speedHigh Energy Physics::ExperimentNeutrino
researchProduct

Optimal ferromagnetically-coated carbon nanotube tips for ultra-high resolution magnetic force microscopy

2013

Using single-walled carbon nanotubes homogeneously coated with ferromagnetic metal as ultra-high resolution magnetic force microscopy probes, we investigate the key image formation parameters and their dependence on coating thickness. The crucial step of introducing molecular beam epitaxy for deposition of the magnetic coating allows highly controlled fabrication of tips with small magnetic volume, while retaining high magnetic anisotropy and prolonged lifetime characteristics. Calculating the interaction between the tips and a magnetic sample, including hitherto neglected thermal noise effects, we show that optimal imaging is achieved for a finite, intermediate-thickness magnetic coating, …

Materials scienceFabrication530 PhysicsBioengineeringNanotechnologyddc:500.202 engineering and technologyCarbon nanotubeengineering.material01 natural scienceslaw.inventionCoatinglaw0103 physical sciencesGeneral Materials ScienceElectrical and Electronic Engineering010302 applied physicsbusiness.industryMechanical EngineeringResolution (electron density)General Chemistry530 Physik021001 nanoscience & nanotechnologyMagnetic anisotropyFerromagnetismMechanics of MaterialsengineeringOptoelectronicsMagnetic force microscope0210 nano-technologybusinessMolecular beam epitaxyNanotechnology
researchProduct

International Scoping Study (ISS) for a future neutrino factory and Super-Beam facility. Detectors and flux instrumentation for future neutrino facil…

2009

Technical report by The ISS Detector Working Group; This report summarises the conclusions from the detector group of the International Scoping Study of a future Neutrino Factory and Super-Beam neutrino facility. The baseline detector options for each possible neutrino beam are defined as follows: 1. A very massive (Megaton) water Cherenkov detector is the baseline option for a sub-GeV Beta Beam and Super Beam facility. 2. There are a number of possibilities for either a Beta Beam or Super Beam (SB) medium energy facility between 1-5 GeV. These include a totally active scintillating detector (TASD), a liquid argon TPC or a water Cherenkov detector. 3. A 100 kton magnetized iron neutrino det…

Particle physicsneutrino factoryCherenkov detectorPhysics::Instrumentation and DetectorsAstrophysics::High Energy Astrophysical PhenomenaBeam-line instrumentation (beam position and profile monitorsddc:500.27. Clean energy01 natural sciencesBunch length monitors)law.inventionNuclear physicsneutrinolaw0103 physical sciencesbeam-intensity monitorsneutrino oscillation[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]Detectors and Experimental Techniques010306 general physicsInstrumentationbeam-intensity monitorMathematical PhysicsdetectorsPhysicsMuon010308 nuclear & particles physicsLarge detector systems for particle and astroparticle physicsDetectorFísicaBeam-intensity monitorsFIS/01 - FISICA SPERIMENTALENeutrino detectorLarge detector systems for particle and astroparticle physicBeam-line instrumentation (beam position and profile monitorbunch length monitors)Physics::Accelerator PhysicsNeutrino FactoryHigh Energy Physics::ExperimentCloud chamberNeutrinoBeam (structure)
researchProduct

Measurement of Neutrino Oscillation Parameters from Muon Neutrino Disappearance with an Off-Axis Beam

2013

The T2K Collaboration reports a precision measurement of muon neutrino disappearance with an off-axis neutrino beam with a peak energy of 0.6 GeV. Near detector measurements are used to constrain the neutrino flux and cross section parameters. The Super-Kamiokande far detector, which is 295 km downstream of the neutrino production target, collected data corresponding to 3.01 x 10(20) protons on target. In the absence of neutrino oscillations, 205 +/- 17 (syst) events are expected to be detected while only 58 muon neutrino event candidates are observed. A fit to the neutrino rate and energy spectrum, assuming three neutrino flavors and normal mass hierarchy yields a best-fit mixing angle sin…

Particle physicsPhysics::Instrumentation and DetectorsSolar neutrinoAstrophysics::High Energy Astrophysical PhenomenaGeneral Physics and AstronomyFluxFOS: Physical sciencesddc:500.201 natural sciences7. Clean energyHigh Energy Physics - ExperimentNuclear physicsHigh Energy Physics - Experiment (hep-ex)0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Muon neutrino010306 general physicsNeutrino oscillationPhysics010308 nuclear & particles physics4. EducationHigh Energy Physics::PhenomenologyDetectorSolar neutrino problemNeutrino detectorMeasurements of neutrino speedFísica nuclearHigh Energy Physics::ExperimentNeutrino
researchProduct

Precision electroweak measurements on the Z resonance

2005

We report on the final electroweak measurements performed with data taken at the Z resonance by the experiments operating at the electron-positron colliders SLC and LEP. The data consist of 17 million Z decays accumulated by the ALEPH, DELPHI, L3 and OPAL experiments at LEP, and 600 thousand Z decays by the SLD experiment using a polarised beam at SLC. The measurements include cross-sections, forward-backward asymmetries and polarised asymmetries. The mass and width of the Z boson, $\MZ$ and $\GZ$, and its couplings to fermions, for example the $\rho$ parameter and the effective electroweak mixing angle, are precisely measured. The number of light neutrino species is determined to be 2.9840…

Top quarkFORWARD-BACKWARD ASYMMETRYPARTICLE PHYSICS; LARGE ELECTRON POSITRON COLLIDER; ALEPH; DELPHI; L3; OPALGeneral Physics and Astronomy01 natural sciences7. Clean energyHigh Energy Physics - ExperimentSettore FIS/04 - Fisica Nucleare e SubnucleareHigh Energy Physics - Experiment (hep-ex)High Energy Physics - Phenomenology (hep-ph)electron-positron physics[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Electroweak interactionPhysicsQuantum chromodynamicsOPALElectron–positron physics; Electroweak interactions; Decays of heavy intermediate gauge bosons; Fermion–antifermion production; Precision measurements at the Z resonance; Tests of the Standard Model; Radiative corrections; Effective coupling constants; Neutral weak current; Z boson; W boson; Top quark; Higgs bosonParticle physics - ExperimentPhysicsSettore FIS/01 - Fisica SperimentaleElectroweak interactionFORWARD-BACKWARD ASYMMETRY; FERMION-PAIR PRODUCTION; HADRONIC-Z-DECAYS; TOP-QUARK MASS; ANGLE BHABHA SCATTERING; W-BOSON MASS; CROSS-SECTION ASYMMETRY; Z-LINE-SHAPE; SEMILEPTONIC BRANCHING RATIOS; CARLO EVENT GENERATORdecays of heavy intermediate gauge bosons; effective coupling constants; electron-positron physics; electroweak interactions; fermion-antifermion production; higgs boson; neutral weak current; precision measurements at the z resonance; radiative corrections; tests of the standard model; top quark; w boson; z bosonRadiative correctionsALEPHLARGE ELECTRON POSITRON COLLIDERRadiative correctionHigh Energy Physics - PhenomenologyFIS/01 - FISICA SPERIMENTALEDecays of heavy intermediate gauge bosonsL3Z-LINE-SHAPEHiggs bosonFERMION-PAIR PRODUCTIONPARTICLE PHYSICSFísica nuclearNeutrinoFermion–antifermion productionPrecision measurements at the Z resonanceTests of the Standard ModelParticle physicsZ bosonfermion-antifermion productionElectroweak interactionsHiggs bosonFOS: Physical sciencesddc:500.2Elementary particle physics ; z boson ; LEP ; electroweakDecays of heavy intermediate gauge bosonEffective coupling constantPartícules (Física nuclear)Standard ModelNeutral weak currentelectroweak theory Z boson DELPHI ALEPH OPAL L30103 physical sciencesANGLE BHABHA SCATTERINGCROSS-SECTION ASYMMETRYSEMILEPTONIC BRANCHING RATIOS010306 general physicsTOP-QUARK MASSEffective coupling constantsDELPHICoupling constantElectron–positron physics010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyFermionCARLO EVENT GENERATORTop quarkW-BOSON MASSFORWARD-BACKWARD ASYMMETRY FERMION-PAIR PRODUCTION HADRONIC-Z-DECAYS TOP-QUARK MASS ANGLE BHABHA SCATTERING W-BOSON MASS CROSS-SECTION ASYMMETRY Z-LINE-SHAPE SEMILEPTONIC BRANCHING RATIOS CARLO EVENT GENERATOR[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph]Experimental High Energy PhysicsElectron–positron physicW bosonHigh Energy Physics::ExperimentFIS/04 - FISICA NUCLEARE E SUBNUCLEAREHADRONIC-Z-DECAYSPHYSICS REPORTS-REVIEW SECTION OF PHYSICS LETTERS
researchProduct