0000000000585641

AUTHOR

Bernard Refouvelet

0000-0002-7939-1600

showing 3 related works from this author

Structure elucidation of benzopyran-2-ol in solution and in solid state following the reduction of coumarin by DIBAL-H

2001

Lactols are compounds of increasing interest in the synthesis of active pharmaceutical derivatives. Nevertheless, the product obtained by the reduction of the carbonyl group of coumarin has been described only twice, and without definition of its precise chemical structure. Since these studies, doubts have been raised about the existence of a monomeric or dimeric form. Our study has led us to conclude definitely that the single dimeric form exists and to precisely define the spectral properties of the two diastereoisomers.

chemistry.chemical_classificationchemistry.chemical_compoundchemistryBicyclic moleculeLactolStereochemistryChemical structureAcetalDiastereomerGeneral ChemistryChemical synthesisLactoneBenzopyranComptes Rendus de l'Académie des Sciences - Series IIC - Chemistry
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Synthesis and stereochemical studies of 2-substituted thiazolidine-4-carboxamide derivatives

2000

A series of new 2-substituted thiazolidine-4-carboxamide derivatives which have potentially useful immunological properties, have been synthesized in a stereoselective manner by coupling 2-subsituted thiazolidine-4-carboxylic acids with amines or amino esters. The structure of these compounds was established by combination of NMR methods and by X-ray analysis.

10120 Department of Chemistrychemistry.chemical_compoundAmino esterschemistrymedicine.drug_classStereochemistryOrganic ChemistryThiazolidine540 ChemistrymedicineCarboxamideStereoselectivity1605 Organic Chemistry
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ChemInform Abstract: Synthesis and Stereochemical Studies of 2-Substituted Thiazolidine-4-carboxamide Derivatives.

2010

A series of new 2-substituted thiazolidine-4-carboxamide derivatives which have potentially useful immunological properties, have been synthesized in a stereoselective manner by coupling 2-subsituted thiazolidine-4-carboxylic acids with amines or amino esters. The structure of these compounds was established by combination of NMR methods and by X-ray analysis.

chemistry.chemical_compoundchemistryAmino estersmedicine.drug_classStereochemistryThiazolidinemedicineCarboxamideStereoselectivityGeneral MedicineCombinatorial chemistryChemInform
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