6533b830fe1ef96bd1296ea4

RESEARCH PRODUCT

ChemInform Abstract: Synthesis and Stereochemical Studies of 2-Substituted Thiazolidine-4-carboxamide Derivatives.

Bernard RefouveletMarek M. KubickiGrégorio CriniJean-françois RobertNadia PellegriniOlivier Blacque

subject

chemistry.chemical_compoundchemistryAmino estersmedicine.drug_classStereochemistryThiazolidinemedicineCarboxamideStereoselectivityGeneral MedicineCombinatorial chemistry

description

A series of new 2-substituted thiazolidine-4-carboxamide derivatives which have potentially useful immunological properties, have been synthesized in a stereoselective manner by coupling 2-subsituted thiazolidine-4-carboxylic acids with amines or amino esters. The structure of these compounds was established by combination of NMR methods and by X-ray analysis.

https://doi.org/10.1002/chin.200121173