6533b829fe1ef96bd128adca

RESEARCH PRODUCT

Synthesis and stereochemical studies of 2-substituted thiazolidine-4-carboxamide derivatives

Grégorio CriniBernard RefouveletOlivier BlacqueMarek M. KubickiJean-françois RobertNadia Pellegrini

subject

10120 Department of Chemistrychemistry.chemical_compoundAmino esterschemistrymedicine.drug_classStereochemistryOrganic ChemistryThiazolidine540 ChemistrymedicineCarboxamideStereoselectivity1605 Organic Chemistry

description

A series of new 2-substituted thiazolidine-4-carboxamide derivatives which have potentially useful immunological properties, have been synthesized in a stereoselective manner by coupling 2-subsituted thiazolidine-4-carboxylic acids with amines or amino esters. The structure of these compounds was established by combination of NMR methods and by X-ray analysis.

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