0000000000606231
AUTHOR
Francesco Petrucci
Suzuki-Miyaura cross-coupling of arenediazonium salts catalyzed by alginate/gellan-stabilized palladium nanoparticles under aerobic conditions in water
The use of palladium nanoparticles stabilized by natural. beads made of an alginate/gellan mixture in the Suzuki-Miyaura cross-coupling reaction of arenediazonium. tetrafluoroborates with potassium aryltrifluoroborates. (1 : 1 molar ratio) with loading as low as 0.01–0.002. mol% under aerobic, phosphine-, and base-free conditions. in water is described. The catalyst system can be reused. several times without significant loss of activity.
Human primary macrophages scavenge AuNPs and eliminate it through exosomes. A natural shuttling for nanomaterials.
Abstract The use of nanomaterials is increasing but the real risk associated with their use in humans has to be defined. In fact, nanomaterials tend to accumulate in organs over a long period of time and are slowly degraded or eliminated by the body. Exosomes are nanovesicles actively shuttle molecules, including chemical products and metals, through the body. Macrophages scavenge the body from both organic and inorganic substances, and they use to release high amounts of exosomes. We hypothesized that macrophages may have a role in eliminating nanomaterials through their exosomes. We treated human primary macrophages with 20 nm gold nanoparticles (AuNPs), analyzing the presence of AuNPs in…