Optical and electrochemical DNA nanobiosensors
In the past two decades, nanoscale advanced materials have been explored for biosensing molecules, so new horizons have opened up for identifying and quantifying biomolecules, and possible early diagnosis of diseases. DNA nanobiosensors show promise. This article provides an overview on their optical and electrochemical aspects. We discuss recent progress in this field, describing basic concepts of molecular beacons and quantum dots as optical nano-imaging systems. Also, carbon nanotubes provide a platform for development and advancement of electrochemical DNA nanobiosensors, which are increasingly being implemented as robust tools for detection in biomedical sciences. Refereed/Peer-reviewed
Advances in detection of fastidious bacteria: From microscopic observation to molecular biosensors
Abstract Identification of pathogens and diagnosis of infections are important health challenges, especially in the case of fastidious bacteria which are those difficult-to-grow. A fastidious organism is any organism that has a complex nutritional requirement. Additionally, a fastidious microorganism will only grow when specific nutrients are included in the culture medium. These bacteria can cause serious diseases whose detection and monitoring is critical in many cases. The oldest detection methods are based on simple microscopy observation and staining, after culture on selective growth media, but often do not provide a clear answer. Some new molecular approaches, such as DNA-based seque…