0000000000609560
AUTHOR
Carles Serrat
Frequentist and Bayesian approaches for a joint model for prostate cancer risk and longitudinal prostate-specific antigen data
The paper describes the use of frequentist and Bayesian shared-parameter joint models of longitudinal measurements of prostate-specific antigen (PSA) and the risk of prostate cancer (PCa). The motivating dataset corresponds to the screening arm of the Spanish branch of the European Randomized Screening for Prostate Cancer study. The results show that PSA is highly associated with the risk of being diagnosed with PCa and that there is an age-varying effect of PSA on PCa risk. Both the frequentist and Bayesian paradigms produced very close parameter estimates and subsequent 95% confidence and credibility intervals. Dynamic estimations of disease-free probabilities obtained using Bayesian infe…
Polarization phenomena in a laser coherently pumped by a linearly polarized field
The field intensity and polarization behaviour of an optically pumped laser is investigated in different operating conditions. For a linearly polarized pump field, a strong gain anisotropy is induced which favours generation of light with a polarization parallel to that of the pump field. Thus gain anisotropy can be counterbalanced by cavity-loss anisotropy only at low pumping field intensities, and the interplay between both types of anisotropy leads to polarization switching phenomena. In contrast to the case of the incoherently pumped laser, the decay rate for the magnetic dipole induced on the J = 1 level plays a minor role in determining the polarization dynamics. The influence of a lo…