0000000000611172

AUTHOR

Sandra Sázelová

showing 2 related works from this author

The evolution and changing ecology of the African hominid oral microbiome

2021

Significance The microbiome plays key roles in human health, but little is known about its evolution. We investigate the evolutionary history of the African hominid oral microbiome by analyzing dental biofilms of humans and Neanderthals spanning the past 100,000 years and comparing them with those of chimpanzees, gorillas, and howler monkeys. We identify 10 core bacterial genera that have been maintained within the human lineage and play key biofilm structural roles. However, many remain understudied and unnamed. We find major taxonomic and functional differences between the oral microbiomes of Homo and chimpanzees but a high degree of similarity between Neanderthals and modern humans, incl…

Neanderthalbindinggut microbiomemicrobiomeprimatePrehistòriaNeanderthalEvolutionsbiologiPrimatesalivary amylasePhylogeny0303 health sciencesMultidisciplinaryEcologyGeographybiologyEcologyMicrobiotaHuman microbiomeancientHominidae402SH6_2Biological SciencesBiological Evolutiongenomes suggestHuman evolution[SDE]Environmental SciencesOral MicrobiomeR-packagePan troglodytesdental plaque[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and PrehistoryEcology (disciplines)Socio-culturaleMicrobiologysalivary alpha-amylase03 medical and health sciencesbiology.animalDental calculus; microbiome; Neanderthal; primate; salivary amylaseAnimalsHumansMicrobiomevisualization030304 developmental biologyMouthperiodontal-diseaseEvolutionary BiologyGorilla gorillaBacteria030306 microbiologydental calculusDNAMikrobiologiBiofilmsFOS: Biological sciencesAnthropologyAfricaUpper PaleolithicMetagenome
researchProduct

Palaeogenomics of Upper Palaeolithic to Neolithic European hunter-gatherers

2023

Acknowledgements: The authors thank G. Marciani and O. Jöris for comments on archaeology; C. Jeong, M. Spyrou and K. Prüfer for comments on genetics; M. O’Reilly for graphical support for Fig. 5 and Extended Data Fig. 9; the entire IT and laboratory teams at the Department of Archaeogenetics of MPI-SHH for technical assistance; M. Meyer and S. Nagel for support with single-stranded library preparation; K. Post, P. van Es, J. Glimmerveen, M. Medendorp, M. Sier, S. Dikstra, M. Dikstra, R. van Eerden, D. Duineveld and A. Hoekman for providing access to human specimens from the North Sea (The Netherlands); M. D. Garralda and A. Estalrrich for providing access to human specimens from La Riera (S…

HistoryAncient dnaInteractionsCave/45/23AdmixtureSettore BIO/08 - Antropologia/631/208/457/631/181/276160 Other humanitiesContaminationHumansHuntingPalaeogenomicsPopulation-structureArchaeology ; Biological anthropology ; Evolutionary genetics ; Population geneticsHistory AncientHuman evolutionDiversityOccupationMultidisciplinary/45Genome HumanarticlePaleontologyLast glacial maximumHuman GeneticsGene PoolGenomics/631/181/19/2471PleistoceneEuropeGenomic transformationsArchaeology/631/181/2474AnthropologyHunter-gatherersGenome sequence
researchProduct