0000000000620498

AUTHOR

Jack A. T. C. Parker

showing 3 related works from this author

Outcome after mitral valve operations with depressed left ventricular function.

2012

We retrospectively investigated 42 patients (27 men, 15 women; mean age, 67 years) with severe mitral valve incompetence and endstage cardiomyopathy (ejection fraction <30%) who were operated on between January 2002 and March 2009. Of these, 14 were in New York Heart Association class IV, and 27 were in class III. The etiology was ischemic in 18 patients and idiopathic dilated in 24. Mitral valve repair was performed in 25 patients, and 17 had mitral valve replacement. The mean logistic EuroSCORE was 33.41. The mean follow-up was 44.52 months. There were no perioperative deaths. Three patients died within 30 days postoperatively. Thirty-day mortality was lower than predicted by EuroSCOR…

Pulmonary and Respiratory MedicineAdultMaleReoperationmedicine.medical_specialtyTime Factorsmedicine.medical_treatmentCardiomyopathyKaplan-Meier EstimateRisk AssessmentSeverity of Illness IndexVentricular Function LeftVentricular Dysfunction LeftRisk FactorsInternal medicineMitral valveGermanymedicineHumansCardiac Surgical ProceduresSurvival rateAgedProportional Hazards ModelsRetrospective StudiesAged 80 and overHeart Valve Prosthesis ImplantationMitral valve repairEjection fractionbusiness.industryMitral valve replacementMitral Valve InsufficiencyEuroSCOREStroke VolumeGeneral MedicinePerioperativeMiddle Agedmedicine.diseaseSurgerymedicine.anatomical_structureLogistic ModelsTreatment OutcomeMultivariate AnalysisCardiologyMitral ValveSurgeryFemaleCardiology and Cardiovascular MedicinebusinessCardiomyopathiesAsian cardiovascularthoracic annals
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Symptomatic atherosclerotic occlusive disease of all supra-aortic arch vessels treated with total aortic arch rerouting.

2011

We present an uncommon case of symptomatic atherosclerotic occlusive disease of all supra-aortic arch vessels and its surgical treatment by total aortic arch rerouting after endarteriectomy of all target vessels.

Pulmonary and Respiratory MedicineAortic archmedicine.medical_specialtyAortographymedicine.medical_treatmentAortic DiseasesHemodynamicsAorta ThoracicConstriction PathologicEndarterectomyAortographySeverity of Illness IndexMagnetic resonance angiographyBlood Vessel Prosthesis Implantationmedicine.arteryInternal medicinemedicineThoracic aortaHumansArchEndarterectomyAgedAortamedicine.diagnostic_testbusiness.industryHemodynamicsAtherosclerosisTreatment OutcomeRegional Blood Flowcardiovascular systemCardiologySurgeryFemaleCardiology and Cardiovascular MedicinebusinessTomography X-Ray ComputedMagnetic Resonance AngiographyInteractive cardiovascular and thoracic surgery
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Oxygen Radical Scavengers

2010

The myocardium can tolerate only relatively short periods of total myocardial ischemia without myocardial cell death. Following short ischemic periods, ischemic damage is reversible by reperfusion. However, with increasing duration and severity of ischemia, the damage inflicted to cardiomyocytes following reperfusion becomes irreversible. The combined pathologic events in the myocardium that follow a critical period of ischemia and leading to either reversible or irreversible damage to both cardiomyocytes and cardiac microvasculature is known as ischemia-reperfusion injury (Goldhaber and Weiss 1992).

chemistry.chemical_classificationmedicine.medical_specialtyReactive oxygen speciesMyocardial ischemiabusiness.industryRadicalIschemiaIntracellular reactive oxygen speciesmedicine.diseasechemistry.chemical_compoundchemistryMitochondrial permeability transition poreInternal medicinemedicineCardiologyMyocardial cellcardiovascular diseasesXanthine oxidasebusiness
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