0000000000630634

AUTHOR

Vincenzo Di Lazzaro

showing 2 related works from this author

Second asymptomatic carotid surgery trial (ACST-2): a randomised comparison of carotid artery stenting versus carotid endarterectomy.

2021

Summary Background Among asymptomatic patients with severe carotid artery stenosis but no recent stroke or transient cerebral ischaemia, either carotid artery stenting (CAS) or carotid endarterectomy (CEA) can restore patency and reduce long-term stroke risks. However, from recent national registry data, each option causes about 1% procedural risk of disabling stroke or death. Comparison of their long-term protective effects requires large-scale randomised evidence. Methods ACST-2 is an international multicentre randomised trial of CAS versus CEA among asymptomatic patients with severe stenosis thought to require intervention, interpreted with all other relevant trials. Patients were eligib…

Malemedicine.medical_specialtyTime FactorsTime Factormedicine.medical_treatmentCarotid StenosiMEDLINECarotid endarterectomyRate ratioRisk AssessmentAsymptomaticlaw.inventionRandomized controlled triallawRisk Factorscarotid artery stenting (CAS); carotid endarterectomy (CEA)StentmedicineHumansCarotid StenosisStrokeEndarterectomyAgedEndarterectomy Carotidbusiness.industrycarotid arteryRisk FactorArticlesGeneral Medicinetrialmedicine.diseaseSettore MED/22 - CHIRURGIA VASCOLARESurgeryStrokeStenosisTreatment Outcomecarotid artery stenting (CAS)Settore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLAREFemaleStentsHuman medicinemedicine.symptomcarotid endarterectomy (CEA)businessHumanLancet (London, England)
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Extremely Low Frequency Magnetic Fields Do Not Affect LTP-Like Plasticity in Healthy Humans.

2020

Introduction: Several studies explored, in vitro, the biological effects of extremely low-frequency magnetic fields (ELF-MFs) and reported the induction of functional changes in neuronal activity. In particular, ELF-MFs can influence synaptic plasticity both in-vitro and in animal models. Indeed, some studies reported an increase in long-term potentiation (LTP) whereas others suggested its reduction. However, no specific study has investigated such effect in humans. Aims: To evaluate whether ELF-MFs affect the propensity of the human cortex to undergo LTP-like plasticity. Methods: We designed a randomized, single-blind, sham-controlled, cross-over study on 10 healthy subjects. Cortical plas…

brain stimulationStimulationBiologyPlasticitymagnetic fields050105 experimental psychologylcsh:RC321-57103 medical and health sciencesBehavioral Neuroscience0302 clinical medicineNeuroplasticitymedicinePremovement neuronal activity0501 psychology and cognitive sciencesskin and connective tissue diseaseslcsh:Neurosciences. Biological psychiatry. NeuropsychiatryBiological Psychiatrylong-term potentiation05 social sciencesLong-term potentiationextremely low-frequency magnetic fieldsrespiratory systemBrief Research ReportPsychiatry and Mental healthNeuropsychology and Physiological Psychologymedicine.anatomical_structureNeurologyBrain stimulationplasticitySynaptic plasticitylow frequencyNeuroscience030217 neurology & neurosurgeryMotor cortexNeuroscienceFrontiers in human neuroscience
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