0000000000640444

AUTHOR

Sabrina De Castro Brasil

showing 2 related works from this author

Cytotoxicity, antibacterial and physicochemical properties of a new epoxy resin-based endodontic sealer containing calcium hydroxide

2019

Background This study evaluated the cytotoxicity, antibacterial and physicochemical properties of a new epoxy resin-based endodontic sealer containing calcium-hydroxide Sealer Plus. AH Plus was used as a reference for comparison. Material and Methods Cytotoxicity evaluation was performed according to ISO-10993-5 specifications using MTT assay to check the 3T3 cells viability at 1- to 4-week periods. Antibacterial activity was evaluated using a direct contact test against Enterococcus faecalis. Radiopacity, solubility and flow evaluations were performed according to ISO-6876/2012 specifications. Setting time was assessed following the ANSI/ADA-standard-n.57. The pH level was measured at 3,24…

Radiodensity0206 medical engineering02 engineering and technologyEnterococcus faecalisOperative Dentistry and Endodontics03 medical and health scienceschemistry.chemical_compound0302 clinical medicineMTT assayCytotoxicityGeneral DentistryRoot Canal ObturationCalcium hydroxidebiologyChemistryResearch030206 dentistryEpoxybiology.organism_classification:CIENCIAS MÉDICAS [UNESCO]020601 biomedical engineeringvisual_artOBTURAÇÃO DO CANAL RADICULARUNESCO::CIENCIAS MÉDICASvisual_art.visual_art_mediumAntibacterial activityNuclear chemistry
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Distribution of macrophages and plasma cells in apical periodontitis and their relationship with clinical and image data

2017

BACKGROUND Macrophages and plasma cells play a key role in the regulation of innate and adaptive immunity. The aim of this study was to assess the presence of these cells in apical periodontitis and their distribution comparing with clinical and image data. MATERIAL AND METHODS Thirty-three lesions were selected and divided in two groups (17 periapical cysts and 16 periapical granulomas). Immunoreactions using anti-CD68 and anti-CD138 antibodies were carried out; image analysis was performed with an optical microscope and 5 high-power fields from each slide were evaluated leading to an average score of immunoexpression. This mean score was compared between the two groups and correlated with…

0301 basic medicinePathologymedicine.medical_specialtyPeriapical cystPeriapical GranulomaOperative Dentistry and Endodontics03 medical and health sciences0302 clinical medicineMedicineDistribution (pharmacology)General DentistryPeriodontitisbiologybusiness.industryCD68ResearchSignificant difference030206 dentistry:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseAcquired immune system030104 developmental biologyUNESCO::CIENCIAS MÉDICASbiology.proteinAntibodybusinessJournal of Clinical and Experimental Dentistry
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