0000000000646293
AUTHOR
F Blasco Gómez
showing 4 related works from this author
Generalised H-point standard addition method for the isolation of the analyte signal from the sample signal when coelution of unknown compounds occur…
1999
The generalised H-point standard addition method (GHPSAM) is proposed for isolating the analytical signal of an analyte from the signal of an unknown sample. Samples containing two and three coeluting compounds have been analysed. The accuracy of the predictions depends on the shape of the analyte and interferent spectra but not on the degree of chromatographic overlap. This methodology involves the location of linear intervals for the unknown interference spectrum from the spectrum of the sample. Once the linear interval has been found the selection of three wavelengths within the interval will allow the cancellation of the signal of the unknown interferent. The method has been applied to …
The H-point and generalized H-point standard additions methods for flow injection procedures.
1997
This paper establishes the fundamentals of the H-point standard additions method (HPSAM) and generalized H-point standard additions method (GHPSAM) in the flow injection technique. Two kinds of analytical signals can be employed, FIA peaks and spectra. Different analytical problems have been studied: determinations of one analyte in the presence or absence of matrix effect when different blank features are present, and determination of two analytes in the presence of blank bias error affecting the development of one of them. The determination of chloride with mercury thiocyanate which presents a matrix effect, and the determinations of calcium and/or magnesium with arsenazo III are examined…
A chemometric study of the simultaneous determination of calcium and magnesium in natural waters
1999
A method for the simultaneous spectrophotometric determination of calcium and magnesium in mineral waters with an FIA system is tested. The method is based on the reaction between the analytes and arsenazo(III) at pH 8.5. The calculations of the amounts of both analytes in the samples are carried out with the H-point standard addition method (HPSAM) for ternary mixtures, and with a partial least squares (PLS) model after a proper variable selection. The results obtained for the determination of calcium were comparable using both methods. The employment of the HPSAM brings to our attention the influence of the calcium concentration in the sample to the development of the reaction between mag…
Creatinine determination in urine samples by batchwise kinetic procedure and flow injection analysis using the Jaffé reaction: chemometric study
2001
The classical Jaffé reaction for the determination of creatinine in urine samples is tested. A comparative study of the main analytical characteristics focussed to minimize the bias error and improve the precision, for the batchwise and flow injection (FI) methods is realized. Also, the effect of the albumin concentration in the determination of creatinine has been studied. Different analytical signals were studied. Absorbance increments at different times permit to estimate the creatinine concentration free from bias error in urine by the batchwise method using the calibration graph obtained with creatinine standards and no measurement of the blank solution is needed. The lineal interval w…