0000000000651299

AUTHOR

Katarzyna Kotfis

showing 4 related works from this author

The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (≥ 80 years)

2017

Purpose: Very old critical ill patients are a rapid expanding group in the ICU. Indications for admission, triage criteria and level of care are frequently discussed for such patients. However, most relevant outcome studies in this group frequently find an increased mortality and a reduced quality of life in survivors. The main objective was to study the impact of frailty compared with other variables with regards to short-term outcome in the very old ICU population. Methods: A transnational prospective cohort study from October 2016 to May 2017 with 30 days follow-up was set up by the European Society of Intensive Care Medicine. In total 311 ICUs from 21 European countries participated. Th…

MaleTime FactorsOutcome AssessmentFrail Elderly/statistics & numerical data[SDV]Life Sciences [q-bio]HSJ UCIPassiveCritical Care and Intensive Care MedicineFrailty/classification/diagnosis/mortality/therapySeverity of Illness IndexSeverity of illneElderly0302 clinical medicineQuality of lifeElderly; Frailty; ICU; Mortality; Octogenarians; Severity of illness; Aged 80 and over; Critical Illness; Europe; Euthanasia Passive; Female; Frail Elderly; Frailty; Geriatric Assessment; Humans; Intensive Care Units; Length of Stay; Male; Outcome Assessment Health Care; Proportional Hazards Models; Prospective Studies; Quality of Life; Severity of Illness Index; Time Factors; Hospital MortalityOutcome Assessment Health Care80 and overProspective StudiesHospital Mortality030212 general & internal medicineProspective cohort studyAged 80 and overeducation.field_of_studyddc:617FrailtyMortality rate[SDV] Life Sciences [q-bio]EuropeIntensive Care UnitsLength of Stay/statistics & numerical dataCohortIntensive Care Units/statistics & numerical dataCritical IllneFemaleSOFA scoreHumanmedicine.medical_specialtyOctogenariansTime FactorCritical IllnessFrail ElderlyIntensive Care UnitPopulationINTENSIVE-CARESeverity of illnessEurope/epidemiologyOutcome Assessment (Health Care)03 medical and health sciencesOctogenarianIntensive careSeverity of illnessJournal ArticlemedicineHumansCOHORTMortalityOctogenarinansIntensive care medicineeducationGeriatric AssessmentAgedProportional Hazards ModelsOLDEREuthanasiabusiness.industry030208 emergency & critical care medicineLength of StayEuthanasia PassiveHealth CareProspective StudieCritical Illness/mortalityUNITICUEmergency medicineProportional Hazards ModelQuality of LifebusinessIntensive Care Medicine
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Potentially Detrimental Effects of Hyperosmolality in Patients Treated for Traumatic Brain Injury

2021

Hyperosmotic therapy is commonly used to treat intracranial hypertension in traumatic brain injury patients. Unfortunately, hyperosmolality also affects other organs. An increase in plasma osmolality may impair kidney, cardiac, and immune function, and increase blood–brain barrier permeability. These effects are related not only to the type of hyperosmotic agents, but also to the level of hyperosmolality. The commonly recommended osmolality of 320 mOsm/kg H2O seems to be the maximum level, although an increase in plasma osmolality above 310 mOsm/kg H2O may already induce cardiac and immune system disorders. The present review focuses on the adverse effects of hyperosmolality on the function…

medicine.medical_specialtyKidneyOsmotic concentrationTraumatic brain injurybusiness.industryosmolar gapmannitolRGeneral MedicineReviewmedicine.diseaseHypertonic salinePlasma osmolalitymedicine.anatomical_structureEndocrinologyImmune systemInternal medicineRenal physiologymedicineMedicineAdverse effectbusinessosmolalitytraumatic brain injury (TBI)hypertonic salineJournal of Clinical Medicine
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Changes in Subendocardial Viability Ratio in Traumatic Brain Injury Patients

2021

Background: Traumatic brain injury (TBI) is often associated with cardiac dysfunction, which is a consequence of the brain–heart cross talk. The subendocardial viability ratio (SEVR) is an estimate...

AdultMaleDecompressive Craniectomymedicine.medical_specialtyTraumatic brain injurymedicine.medical_treatment050105 experimental psychologyCardiac dysfunction03 medical and health sciences0302 clinical medicineInternal medicineBrain Injuries TraumaticmedicineHumans0501 psychology and cognitive sciencesbusiness.industryGeneral Neuroscience05 social sciencesBrainmedicine.diseaseMagnetic Resonance ImagingTreatment OutcomeBrain InjuriesCardiologyFemaleDecompressive craniectomyTherapy monitoringbusiness030217 neurology & neurosurgeryBrain Connectivity
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Decompressive Craniectomy Improves QTc Interval in Traumatic Brain Injury Patients

2020

Background: Traumatic brain injury (TBI) is commonly associated with cardiac dysfunction, which may be reflected by abnormal electrocardiograms (ECG) and/or contractility. TBI-related cardiac disorders depend on the type of cerebral injury, the region of brain damage and the severity of the intracranial hypertension. Decompressive craniectomy (DC) is commonly used to reduce intra-cranial hypertension (ICH). Although DC decreases ICH rapidly, its effect on ECG has not been systematically studied. The aim of this study was to analyze the changes in ECG in patients undergoing DC. Methods: Adult patients without previously known cardiac diseases treated for isolated TBI with DC were studied. EC…

the index of cardio-electrophysiological balanceAdultMalemedicine.medical_specialtyDecompressive CraniectomyAdolescentIntracranial PressureTraumatic brain injuryHealth Toxicology and Mutagenesismedicine.medical_treatmentelectrocardiographylcsh:MedicineBrain damage030204 cardiovascular system & hematologyQT intervalArticleContractility03 medical and health sciencesQRS complexYoung Adult0302 clinical medicineInternal medicineBrain Injuries TraumaticmedicineHumanscardiovascular diseasesCardiac disordersmedicine.diagnostic_testbusiness.industrytraumatic brain injurylcsh:RPublic Health Environmental and Occupational Healthcardiac disordersArrhythmias CardiacMiddle Agedmedicine.diseaseTreatment Outcomecardiac arrhythmiasCardiologycardiovascular systemDecompressive craniectomyFemalemedicine.symptomIntracranial HypertensionbusinessElectrocardiography030217 neurology & neurosurgeryInternational Journal of Environmental Research and Public Health
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