0000000000652613
AUTHOR
N. Vivona
showing 17 related works from this author
NF-κB is a potential pharmacological target in triple negative breast cancers.
2015
Triple negative breast cancers (TNBCs), characterized by lack of estrogen, progesterone and HER2 receptors, are a highly heterogenous group of tumors which account for about 20% to 25% of all breast cancers. TNBCs are often associated with epithelial-mesenchymal transition and a high propensity for early metastasis. Since no molecularly-targeted therapeutic agents are clinically available for TNBCs, these tumors, which are frequently resistant to cytotoxic chemotherapy, remain difficult to treat. Nevertheless, progress is being made in the finding of molecular alterations typical of TNBCs toward which to focus therapeutic efforts.
Addition reactions of heterocycles—IV
1973
Abstract The reactivity of indole derivatives towards nitrilimines has been studied. Substituents at positions 1, 2 and 3 of the indole ring greatly affect the course of the reaction. 1,3-Dipolar cycloaddition products (3a,8a,dihydropyrazole-[3,4-b]-indole derivatives) and non-cyclic addition products (3-indolyl derivatives) were obtained depending on these substituents. The structures reported were assigned on the basis of satisfactory analytical, spectroscopic and chemical data.
Effectiveness of screening for known mutations in Sicilian patients with "probable" familial hypercholesterolemia.
2002
Background and Aim: More than 750 mutations in the low-density lipoprotein (LDL) receptor gene are currently known to cause familial hypercholesterolemia (FH), but the array of mutations varies considerably in different populations. The definition of essentially all the LDL receptor gene mutations in a population is therefore a prerequisite for the implementation of nation-wide genetic testing for FH. Methods and Results: In this study, a screening strategy based on PCR-enzymatic digestion and PCR-allele specific hybridisation procedures was used to evaluate the frequency distributions of 11 known mutations in a cohort of 214 unrelated subjects meeting the diagnostic criteria of "probable" …
Designing fluorous domains. Synthesis of a series of pyridinium salts bearing a perfluoroalkylated azole moiety
2006
The synthesis of a series of N-methylpyridinium salts bearing a perfluoroalkylated 1,2,4-oxadiazole or 1,2,4-triazole moiety is reported. X-Ray structures of representative perfluoroalkyl-triazolylpyridine (15) and methyl- pyridinium iodide salt (5a) are reported. Their crystal packing clearly shows segregation between the aromatic and parallel double layer fluorinated regions.
CCDC 633320: Experimental Crystal Structure Determination
2008
Related Article: A.P.Piccionello, I.Pibiri, A.Pace, R.A.Raccuglia, S.Buscemi, N.Vivona, G.Giorgi|2007|Heterocycles|71|1529|doi:10.3987/COM-07-11040
CCDC 633321: Experimental Crystal Structure Determination
2008
Related Article: A.P.Piccionello, I.Pibiri, A.Pace, R.A.Raccuglia, S.Buscemi, N.Vivona, G.Giorgi|2007|Heterocycles|71|1529|doi:10.3987/COM-07-11040
CCDC 271045: Experimental Crystal Structure Determination
2005
Related Article: S.Buscemi, A.Pace, A.P.Piccionello, G.Macaluso, N.Vivona, D.Spinelli, G.Giorgi|2005|J.Org.Chem.|70|3288|doi:10.1021/jo047766s
CCDC 630243: Experimental Crystal Structure Determination
2007
Related Article: S.Buscemi, A.Pace, A.P.Piccionello, I.Pibiri, N.Vivona, G.Giorgi, A.Mazzanti, D.Spinelli|2006|J.Org.Chem.|71|8106|doi:10.1021/jo061251e
CCDC 630242: Experimental Crystal Structure Determination
2007
Related Article: S.Buscemi, A.Pace, A.P.Piccionello, I.Pibiri, N.Vivona, G.Giorgi, A.Mazzanti, D.Spinelli|2006|J.Org.Chem.|71|8106|doi:10.1021/jo061251e
CCDC 653860: Experimental Crystal Structure Determination
2008
Related Article: A.P.Piccionello, A.Pace, S.Buscemi, N.Vivona, M.Pani|2008|Tetrahedron|64|4004|doi:10.1016/j.tet.2008.02.047
CCDC 245638: Experimental Crystal Structure Determination
2004
Related Article: A.Pace, I.Pibiri, S.Buscemi, N.Vivona, L.Malpezzi|2004|J.Org.Chem.|69|4108|doi:10.1021/jo049814e
CCDC 279694: Experimental Crystal Structure Determination
2006
Related Article: S.Buscemi, A.Pace, A.P.Piccionello, N.Vivona, M.Pani|2006|Tetrahedron|62|1158|doi:10.1016/j.tet.2005.10.071
CCDC 279693: Experimental Crystal Structure Determination
2006
Related Article: S.Buscemi, A.Pace, A.P.Piccionello, N.Vivona, M.Pani|2006|Tetrahedron|62|1158|doi:10.1016/j.tet.2005.10.071
CCDC 749593: Experimental Crystal Structure Determination
2011
Related Article: A.Terenzi, G.Barone, A.P.Piccionello, G.Giorgi, A.Guarcello, P.Portanova, G.Calvaruso, S.Buscemi, N.Vivona, A.Pace|2010|Dalton Trans.|39|9140|doi:10.1039/c0dt00266f
CCDC 245639: Experimental Crystal Structure Determination
2004
Related Article: A.Pace, I.Pibiri, S.Buscemi, N.Vivona, L.Malpezzi|2004|J.Org.Chem.|69|4108|doi:10.1021/jo049814e
CCDC 653859: Experimental Crystal Structure Determination
2008
Related Article: A.P.Piccionello, A.Pace, S.Buscemi, N.Vivona, M.Pani|2008|Tetrahedron|64|4004|doi:10.1016/j.tet.2008.02.047
CCDC 630241: Experimental Crystal Structure Determination
2007
Related Article: S.Buscemi, A.Pace, A.P.Piccionello, I.Pibiri, N.Vivona, G.Giorgi, A.Mazzanti, D.Spinelli|2006|J.Org.Chem.|71|8106|doi:10.1021/jo061251e