0000000000653999

AUTHOR

Maria Garcia-pous

showing 6 related works from this author

Early lipoic acid intake protects retina of diabetic mice

2008

The aim of this study was to test the effect of lipoic acid treatment on the retina after a short diabetic insult. Diabetes was induced by alloxan and mice were divided into sub-groups; control, diabetic, diabetic+insulin and all groups received+/-lipoic acid (100 mg/kg body weight) for 3 weeks. GSH content, MDA concentration, GPx activity were measured and electroretinograms (ERG) were recorded. Early administration of lipoic acid to diabetic mice prevented the statistically significant decreases of GSH content and GPx activity and normalized MDA concentration. Moreover, lipoic acid restored electroretinogram b-wave amplitude of diabetic animals to control values. Lipoic acid has a protect…

Malemedicine.medical_specialtyAntioxidantgenetic structuresmedicine.medical_treatmentmedicine.disease_causeBiochemistryAntioxidantsDrug Administration ScheduleRetinaDiabetes Mellitus ExperimentalMicechemistry.chemical_compoundMalondialdehydeInternal medicineDiabetes mellitusAlloxanElectroretinographymedicineAnimalsHypoglycemic AgentsInsulinGlutathione PeroxidaseDiabetic RetinopathyThioctic Acidbusiness.industryInsulinGeneral MedicineGlutathionemedicine.diseaseGlutathioneeye diseasesOxidative StressLipoic acidEndocrinologychemistrylipids (amino acids peptides and proteins)sense organsbusinessErgOxidative stressFree Radical Research
researchProduct

Q fever: a new ocular manifestation

2011

P Udaondo1,3, S Garcia-Delpech1,2, D Salom1,2, M Garcia-Pous1, M Diaz-Llopis1,21Department of Ophthalmology, Nuevo Hospital Universitario y Politecnico La Fe, Valencia, Spain; 2Faculty of Medicine, Universitat de València, Valencia, Spain; 3Universidad Cardenal Herrera CEU, Valencia, SpainAbstract: Q Fever is a zoonosis caused by Coxiella burnetii. Ocular manifestations are rare in this infection. We describe the case of a man complaining of an intense retro-orbital headache, fever, arthralgia, and bilateral loss of vision, who showed an anterior uveitis accompanied by exudative bilateral inferior retinal detachment and optic disk edema. At the beginning, a Vogt–Koyanag…

Doxycyclineexudative retinal detachmentmedicine.medical_specialtybiologyVkh syndromebusiness.industryPanuveitispanuveitisRetinal detachmentQ feverCase ReportExudative retinal detachmentRE1-994Coxiella burnetiibiology.organism_classificationmedicine.diseaseVogt-Koyanagi-Harada syndromeComplete resolutioneye diseasesOphthalmologyOphthalmologymedicinebusinessQ fevermedicine.drugClinical Ophthalmology
researchProduct

Intravitreal pegaptanib for refractory macular edema secondary to retinal vein occlusion

2011

Patricia Udaondo1,2, Salvador Garcia-Delpech1,3, David Salom1,3, Maria Garcia-Pous1,3, Manuel Diaz-Llopis1,31Nuevo Hospital Universitario y Politecnico La Fe, Valencia, Spain; 2University Cardenal Herrera CEU, Valencia, Spain; 3Faculty of Medicine, University of Valencia, Valencia, SpainPurpose: To assess the efficacy of intravitreal Pegaptanib sodium (Macugen®) injection in the management of refractory macular edema secondary to branch retinal vein occlusion.Methods: This is a prospective, nonrandomized, interventional case series. Five eyes of five patients with macular edema refractory to either bevacizumab or triamcinolone were treated with intravitreal injection of Pegaptanib s…

medicine.medical_specialtyVisual acuityRetinal VeinTriamcinolone acetonideBevacizumabgenetic structuresBCVAPegaptanibCase Reportpegaptanib sodiumOphthalmologymedicinePegaptanib SodiumMacular edemaBRVObusiness.industryClinical OphthalmologyRE1-994medicine.diseaseeye diseasesSurgeryOphthalmologyMacugen®Branch retinal vein occlusionsense organsmedicine.symptombusinessmedicine.drug
researchProduct

Acute endothelial failure after cosmetic iris implants (NewIris®)

2011

We report a case of an acute endothelial failure after the implantation of a new cosmetic, colored, artificial iris diaphragm implant called NewIris(®). A 21-year-old woman came to us complaining of progressive loss of vision and pain after NewIris lenses had been implanted. Decreased visual acuity, corneal edema, and increased intraocular pressure in both eyes appeared only 3 weeks after the surgery. The lenses were removed as soon as possible but had already severely affected the endothelial cell count. NewIris implants are an alternative to cosmetic contact lenses, but they are not as safe as other phakic anterior chamber intraocular lenses, nor are they a good option for the patient.

Intraocular pressuremedicine.medical_specialtygenetic structuresbusiness.industryCase Reportendothelial failureNewIrisEndothelial cell counteye diseasescosmetic iris implantsSurgeryOphthalmologymedicine.anatomical_structureCorneal edemaIntraocular lensesOphthalmologyDecreased Visual AcuitymedicineImplantsense organsIris (anatomy)businessClinical Ophthalmology (Auckland, N.Z.)
researchProduct

Prophylaxis of Macular Edema with Intravitreal Ranibizumab in Patients with Diabetic Retinopathy after Cataract Surgery: A Pilot Study

2011

The purpose of this study was to evaluate the effectiveness of intravitreal ranibizumab (Lucentis, Genentech, South San Francisco, Calif, USA) combined with cataract surgery for the prevention of clinically significant macular edema (CSME) in patients with diabetic retinopathy (DR). This prospective interventional case series included fifty-four eyes of 54 patients with a previous diagnosis of nonproliferative diabetic retinopathy (NPDR) without macular edema preoperatively. Subjects were assigned in a 1 : 1 ratio to receive an intraoperative intravitreal ranibizumab injection (n=27) or not (control group,n=27) associated with standardised phacoemulsification surgery. The main outcome measu…

medicine.medical_specialtygenetic structuresArticle Subjectbusiness.industrymedicine.medical_treatmentIncidence (epidemiology)After cataractPhacoemulsificationDiabetic retinopathyCataract surgerymedicine.diseaseeye diseasesSurgeryOphthalmologylcsh:Ophthalmologylcsh:RE1-994OphthalmologymedicineClinical StudyIn patientIntravitreal ranibizumabbusinessMacular edemaJournal of Ophthalmology
researchProduct

Acute endothelial failure after cosmetic iris implants (NewIris®)

2011

Maria Garcia-Pous1, Patricia Udaondo2, Salvador Garcia-Delpech2, David Salom1, Manuel Díaz-Llopis21Faculty of Medicine, University of Valencia, Valencia, Spain; 2Ophthalmology Department, Hospital Universitario La Fe, Valencia, SpainAbstract: We report a case of an acute endothelial failure after the implantation of a new cosmetic, colored, artificial iris diaphragm implant called NewIris®. A 21-year-old woman came to us complaining of progressive loss of vision and pain after NewIris lenses had been implanted. Decreased visual acuity, corneal edema, and increased intraocular pressure in both eyes appeared only 3 weeks after the surgery. The lenses were removed as soon as…

genetic structuresClinical Ophthalmologysense organseye diseasesClinical Ophthalmology
researchProduct