0000000000656738

AUTHOR

Miroslav Souček

showing 2 related works from this author

Caffeine and cardiovascular diseases: critical review of current research.

2015

Caffeine is a most widely consumed physiological stimulant worldwide, which is consumed via natural sources, such as coffee and tea, and now marketed sources such as energy drinks and other dietary supplements. This wide use has led to concerns regarding the safety of caffeine and its proposed beneficial role in alertness, performance and energy expenditure and side effects in the cardiovascular system. The question remains "Which dose is safe?", as the population does not appear to adhere to the strict guidelines listed on caffeine consumption. Studies in humans and animal models yield controversial results, which can be explained by population, type and dose of caffeine and low statistica…

DrugSettore BIO/17 - Istologiamedia_common.quotation_subjectmedicine.medical_treatmentPopulationMedicine (miscellaneous)030204 cardiovascular system & hematologyCoffeeToxicology03 medical and health scienceschemistry.chemical_compound0302 clinical medicineMeta-Analysis as TopicEnvironmental healthCaffeinemedicineAnimalsHumanseducationmedia_commonMetabolic Syndromeeducation.field_of_studyNutrition and DieteticsDose-Response Relationship Drugbusiness.industryClinical Studies as TopicInsulin sensitivityHeartStimulantAlertnessDisease Models AnimalEnergy expenditurechemistryCaffeine consumptionCardiovascular diseases Caffeine Cardioprotective effects Pathogenesis Clinical studies Experimental studiesCardiovascular DiseasesBlood VesselsCaffeinebusiness030217 neurology & neurosurgeryEuropean journal of nutrition
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Intra-Dialytic Electrostimulation of Leg Extensors May Improve Exercise Tolerance and Quality of Life in Hemodialyzed Patients

2011

Hemodialyzed (HD) patients with end-stage renal disease (ESRD) exhibit lower fitness as a consequence of chronic uremic changes that trigger various structural, metabolic, and functional abnormalities in skeletal muscles. The aim of this randomized study was to compare the effect of rehabilitation (RHB) training on a bicycle ergometer and electromyostimulation (EMS) of leg extensors in HD patients with ESRD. Thirty-two HD patients (18 men/14 women; mean age 61.1 ± 8.8 years) were randomized into three groups: (i) exercise training (ET; n = 11) on bicycle ergometer 2 × 20 min; (ii) EMS (n = 11) where stimulation (10 Hz) of leg extensors was applied for 60 min; and (iii) controls (CON; n = 10…

medicine.medical_specialtymedicine.medical_treatment030232 urology & nephrologyBiomedical EngineeringMedicine (miscellaneous)Bioengineering030204 cardiovascular system & hematologylaw.inventionBiomaterials03 medical and health sciences0302 clinical medicineRandomized controlled trialQuality of lifelawInternal medicinemedicineProspective cohort studyWalking testbusiness.industryGeneral Medicinemedicine.diseaseUremiaMuscle atrophy3. Good healthCardiologyPhysical therapyBicycle ergometerHemodialysismedicine.symptombusinessArtificial Organs
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