0000000000667007
AUTHOR
Josep Prat
Factores predisponentes a la infección nosocomial en el ictus agudo y su influencia en la morbimortalidad
Fundamento y objetivo El ictus constituye una causa importante de mortalidad y discapacidad. El objetivo del presente estudio es identificar los factores predictores de infeccion nosocomial en la fase aguda del ictus y como esta influye en la morbimortalidad de esta enfermedad. Pacientes y metodo Se ha realizado un estudio prospectivo, observacional y longitudinal de cohortes de pacientes con ictus agudo. El ictus se diagnostico segun la definicion de la Organizacion Mundial de la Salud, actualizada por la Sociedad Espanola de Neurologia. La infeccion nosocomial se definio por los criterios de los Centers for Disease Control y los de la Sociedad Espanola de Enfermedades Infecciosas y Microb…
Field performance of the Abbott RealTime MTB assay for the diagnosis of extrapulmonary tuberculosis in a low-prevalence setting
Introduction: The sensitivities of conventional mycobacterial culture in solid or liquid media and acid-fast bacilli (AFB) smear microscopy for Mycobacterium tuberculosis complex (MTBC) detection in extrapulmonary specimens are suboptimal. We evaluated the field performance of the Abbott RealTime MTB assay for the diagnosis of extrapulmonary tuberculosis in a low-prevalence setting. Methods: The total number of extrapulmonary specimens with mycobacterial culture and PCR results was 566: sterile fluids (n = 278), non-sterile fluids (n = 147), lymph node material (n = 69) tissue biopsies (n = 63), and abscess aspirates (n = 9). A composite standard consisting of mycobacterial culture results,…
Missing Cases of Herpes Simplex Virus (HSV) Infection of the Central Nervous System When the Reller Criteria Are Applied for HSV PCR Testing: a Multicenter Study
ABSTRACT Previous studies suggested that herpes simplex virus (HSV) PCR testing can be safely deferred in patients with normal cerebrospinal fluid (CSF) white blood cell (WBC) counts and protein levels as long as they are older than 2 years of age and are not immunocompromised, the so-called Reller criteria. In this multicenter study, we retrospectively assessed the validity of these screening criteria in our setting. A total of 4,404 CSF specimens submitted for HSV PCR testing to the respective microbiology laboratories at the participating hospitals between 2012 and 2018 were included. Six commercially available HSV PCR assays were used across the participating centers. Ninety-one of the …