0000000000667200

AUTHOR

Liu Zhen

showing 2 related works from this author

Colletotrin: a sesquiterpene lactone from the endophytic fungus Colletotrichum gloeosporioides associated with Trichilia monadelpha

2017

Abstract A new sesquiterpene lactone, namely colletotrin (1), together with two known fungal metabolites (2, 3), was obtained from a rice culture of Colletotrichum gloeosporioides, an endophytic fungus isolated from the stem bark of Cameroonian medicinal plant Trichilia monadelpha (Meliaceae). The structure of the new compound was established on the basis of extensive NMR analysis (1H, 13C, heteronuclear single-quantum coherence and heteronuclear multiple-bond correlation) completed by high-resolution electrospray ionization mass spectroscopy results and by comparison of these data with those of related compounds described in the literature. Their cytotoxic and antibacterial activities agai…

0301 basic medicinechemistry.chemical_classificationMeliaceaebiologyTraditional medicineChemistryElectrospray ionization030106 microbiologyGeneral Chemistrybiology.organism_classificationTrichilia monadelphaSesquiterpene lactoneEndophytePlant use of endophytic fungi in defense03 medical and health sciences030104 developmental biologyHeteronuclear moleculeColletotrichum gloeosporioidesZeitschrift für Naturforschung B
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Chemical constituents from leaves and root bark of Trichilia monadelpha (Meliaceae)

2018

Abstract Two new limonoid derivatives designated, monadelphin A (1) and monadelphin B (2) and two new sesquiterpene derivatives named trichins A (3) and B (4) were isolated together with six known compounds (5–10) from the mixture of methylene chloride/methanol (1:1) extract of leaves and root bark of Trichilia monadelpha (Meliaceae) collected in Cameroon. The structures of the new compounds were unambiguously established by detailed spectroscopic analysis including 1D and 2D NMR data in conjunction with high resolution mass spectrometry data and by comparison of these data with those of related compounds described in the literature. Compounds 1–4 were screened for their cytotoxic potential…

Meliaceaebiology010405 organic chemistryStereochemistryPlant ScienceSesquiterpenebiology.organism_classificationLimonoidTrichilia monadelpha01 natural sciencesBiochemistryChloride0104 chemical sciences010404 medicinal & biomolecular chemistrychemistry.chemical_compoundchemistryvisual_artmedicinevisual_art.visual_art_mediumBarkMethyleneAgronomy and Crop ScienceTwo-dimensional nuclear magnetic resonance spectroscopyBiotechnologymedicine.drugPhytochemistry Letters
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