0000000000671663

AUTHOR

J. Schreiber

showing 3 related works from this author

Farbduplexsonographische Messung der Lymphknotenperfusion: Ein Beitrag zur Diagnostik der zervikalen Metastasierung*

1993

The objective of this study was to find additional sonomorphological criteria for determining the status of enlarged lymph nodes. By using colour-coded duplex sonography the perfusion of 63 lymph nodes in the neck was analysed. The status was confirmed either histologically or clinically (29 metastases from squamous cell carcinomas and 34 acute or chronic inflammatory nodal diseases). A quantitative evaluation of the pulsatility measured in 51 lymph nodes by computing the Pourcelot-Ratio and the Mean Pulsatility Index yielded significant differences between the two groups. By definition of a limiting value of the Pourcelot-Ratio (0.75) for the prediction of benignity, the specificity and th…

medicine.medical_specialtyPathologymedicine.diagnostic_testbusiness.industryBenignityPhysical examinationPulsatility indexmedicine.diseaseNodal diseaseMetastasisOtorhinolaryngologyPartial lossMedicineLymphRadiologybusinessPerfusionLaryngo-Rhino-Otologie
researchProduct

Self-assembled Pt2L2 boxes strongly bind G-quadruplex DNA and influence gene expression in cancer cells

2017

Supramolecular Pt(ii) quadrangular boxes bind native and G-quadruplex DNA motifs in a size-dependent fashion. Three Pt molecular squares of distinct size show biological activity against cancer cells and heavily influence the expression of genes known to form G-quadruplexes in their promoter regions. The smallest Pt-box displays less activity but more selectivity for a quadruplex formed in the c-Kit gene.

010405 organic chemistryChemistrySupramolecular chemistryBiological activity010402 general chemistryG-quadruplex01 natural sciencesMolecular biology0104 chemical sciencesSelf assembledCell biologyInorganic Chemistrychemistry.chemical_compoundG-quadruplex PlatinumSettore CHIM/03 - Chimica Generale E InorganicaGene expressionCancer cellheterocyclic compoundsGeneDNADalton Transactions
researchProduct

Die Rolle der Farbduplexsonographie bei Diagnose und Differentialdiagnose von Glomus-caroticum-Tumoren*

1996

BACKGROUND Currently the diagnosis of tumorous lesions of the carotid bifurcation is the domain of magnetic resonance imaging (MRI) and digital subtraction angiography (DSA). So far, colour Doppler imaging (CDI) has not been playing an important part in this field. The aim of this study was to define the diagnostic value of CDI in the evaluation of these tumours related to the big arteries and to compare the different imaging techniques. PATIENTS AND METHODS 6 female patients with suspected tumours of the carotid bifurcation were examined with CDI. Additionally 5 MRI examinations and 3 preoperative diagnostic DSA examinations were performed in the same patients. Pathologically, there were 4…

medicine.medical_specialtyPathologymedicine.diagnostic_testbusiness.industryExternal carotid arteryMagnetic resonance imagingSympathetic trunkDigital subtraction angiographymedicine.diseaseGlomus tumormedicine.anatomical_structureOtorhinolaryngologyParagangliomamedicine.arteryMedicineCarotid bodyRadiologyInternal carotid arterybusinessLaryngo-Rhino-Otologie
researchProduct