0000000000679193

AUTHOR

Ruud Van Winkel

showing 2 related works from this author

Estimating Exposome Score for Schizophrenia Using Predictive Modeling Approach in Two Independent Samples: The Results From the EUGEI Study

2019

The EUGEI project was supported by the grant agreement HEALTH-F2-2010-241909 from the European Community’s Seventh Framework Programme. The authors are grateful to the patients and their families for participating in the project. They also thank all research personnel involved in the GROUP project, in particular J. van Baaren, E. Veermans, G. Driessen, T. Driesen, E. van’t Hag and J. de Nijs. Bart PF Rutten was funded by a VIDI award number 91718336 from the Netherlands Scientific Organisation.

MalecannabisLogistic regression0302 clinical medicineLasso (statistics)Adverse Childhood ExperiencesStatisticsOdds RatioChild AbusePOLYGENIC RISKpsychosisChildPsychiatrySUMMER BIRTHFramingham Risk Score3. Good healthExposomePsychiatry and Mental healthmachine learningSchizophreniaArea Under CurveFemaleMarijuana UseSeasonsEnvironment And Schizophrenia—Feature Editor: Jim van OsLife Sciences & Biomedicineenvironmentpredictive modelingAdultExposomeDISORDERSrisk scoreYoung Adult03 medical and health sciencesPSYCHOSISmedicineJournal ArticleHumansHearing LossMETAANALYSISDEFICIT SCHIZOPHRENIAENVIRONMENTModels StatisticalScience & Technologychildhood traumaReceiver operating characteristicbusiness.industrySiblingsBullyingBayes TheoremChild Abuse SexualOdds ratiohearing impairmentmedicine.disease030227 psychiatryschizophreniaLogistic ModelsROC CurveSexual abuseCase-Control StudiesbusinessCHILDHOOD ADVERSITIES030217 neurology & neurosurgerywinter birth
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Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations

2014

European Community Recent years have seen considerable progress in epidemiological and molecular genetic research into environmental and genetic factors in schizophrenia, but methodological uncertainties remain with regard to validating environmental exposures, and the population risk conferred by individual molecular genetic variants is small. There are now also a limited number of studies that have investigated molecular genetic candidate gene-environment interactions (G x E), however, so far, thorough replication of findings is rare and G x E research still faces several conceptual and methodological challenges. in this article, we aim to review these recent developments and illustrate h…

URBANICITYSchizophrenia (object-oriented programming)CHILDHOODGenome-wide association studyVARIANTSSocial Environmentpsychosi03 medical and health sciences0302 clinical medicinePSYCHOSISepidemiology; gene-environment interaction; genetics; psychosis; schizophreniaSDG 3 - Good Health and Well-beingRISK-FACTORSettore M-PSI/08 - Psicologia ClinicaGenetic variationHumansGenetic Predisposition to DiseasegeneticspsychosisGENOME-WIDE ASSOCIATIONGeneSettore MED/25 - PsichiatriaMETAANALYSISScale (chemistry)schizophrenia; gene-environment interaction; Psychosis; epidemiology; geneticsGenetic variantsEnvironment and Schizophrenia InvitedCANNABIS USE3. Good health030227 psychiatrygene-environment interactionschizophreniaPsychiatry and Mental healthEvolutionary biology/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingIdentification (biology)Schizophrenic PsychologyepidemiologyPopulation RiskgeneticPsychologyFOLLOW-UP030217 neurology & neurosurgeryFUTURE-DIRECTIONSClinical psychology
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