0000000000686143

AUTHOR

Makela M.

showing 2 related works from this author

Effect of hydrolyzed infant formula vs conventional formula on risk of type 1 diabetes the TRIGR randomized clinical trial

2018

IMPORTANCE Early exposure to complex dietary proteins may increase the risk of type 1 diabetes in children with genetic disease susceptibility. There are no intact proteins in extensively hydrolyzed formulas. OBJECTIVE To test the hypothesis that weaning to an extensively hydrolyzed formula decreases the cumulative incidence of type 1 diabetes in young children. DESIGN, SETTING, AND PARTICIPANTS An international double-blind randomized clinical trial of 2159 infants with human leukocyte antigen-conferred disease susceptibility and a first-degree relative with type 1 diabetes recruited from May 2002 to January 2007 in 78 study centers in 15 countries; 1081 were randomized to be weaned to the…

MaleRiskmedicine.medical_specialtyCaseinBreastfeeding030209 endocrinology & metabolism610 Medicine & health2700 General MedicineEndocrinology and DiabetesDisease-Free Survivallaw.inventionFollow-Up StudieNutrition Policy03 medical and health sciences0302 clinical medicineRandomized controlled trialDouble-Blind MethodSDG 3 - Good Health and Well-beinglawInternal medicineDiabetes mellitusmedicineHumansCumulative incidence030212 general & internal medicineChildInfant Nutritional Physiological PhenomenaOriginal Investigation2. Zero hungerType 1 diabetesbusiness.industryHazard ratioAbsolute risk reductionInfant NewbornCaseinsGeneral Medicineta3121medicine.diseaseInfant Formula3. Good healthDiabetes Mellitus Type 1Infant formula10036 Medical ClinicEndokrinologi och diabetesFemalebusinessHumanFollow-Up Studies
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Is diet partly responsible for differences in COVID-19 death rates between and within countries?

2020

Abstract Reported COVID-19 deaths in Germany are relatively low as compared to many European countries. Among the several explanations proposed, an early and large testing of the population was put forward. Most current debates on COVID-19 focus on the differences among countries, but little attention has been given to regional differences and diet. The low-death rate European countries (e.g. Austria, Baltic States, Czech Republic, Finland, Norway, Poland, Slovakia) have used different quarantine and/or confinement times and methods and none have performed as many early tests as Germany. Among other factors that may be significant are the dietary habits. It seems that some foods largely use…

BLOOD-PRESSUREReviewAngiotensin-converting enzyme; Antioxidant; Coronavirus; Diet; Foodlaw.inventionDietary interventions0302 clinical medicine[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases10183 Swiss Institute of Allergy and Asthma ResearchlawMedicine and Health SciencesImmunology and AllergyMedicine030212 general & internal medicine[SDV.MHEP.ME] Life Sciences [q-bio]/Human health and pathology/Emerging diseases[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseaseseducation.field_of_studyMortality rate3. Good health[SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases2723 Immunology and AllergyAntioxidantAngiotensin-converting enzymeAngiotensin-converting enzyme Antioxidant Coronavirus Diet FoodPulmonary and Respiratory Medicine2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)CoronaviruImmunologyPopulation610 Medicine & healthCOVID-19 ; Food ; Angiotensin-converting enzyme ; Diet ; Antioxidant ; CoronavirusSettore MED/10 - Malattie Dell'Apparato Respiratorio03 medical and health sciencesEnvironmental healthCOVID-19 ; population ; angiotensin-converting enzymeQuarantineeducation2403 ImmunologyANTIHYPERTENSIVE PEPTIDESbusiness.industryRC581-607GENEPOLYMORPHISMDietCoronavirus[SDV.AEN] Life Sciences [q-bio]/Food and Nutrition030228 respiratory system2740 Pulmonary and Respiratory MedicineFoodImmunologic diseases. Allergybusiness[SDV.AEN]Life Sciences [q-bio]/Food and NutritionRegional differencesCoronavirus Infections
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