0000000000703764
AUTHOR
Juan Sanchis Forés
Cocaine-induced coronary thrombosis and acute myocardial infarction
A 26-year-old man was admitted to our hemodynamic laboratory because of an anterior AMI and post myocardial infarction angina. He is an active smoker (10 cigarettes/day) and consumes inhaled cocaine during weekends (the last consumption of cocaine was 1 week ago). No others risk factors were recorded. Initial electrocardiogram shows sinus rhythm and anterior QS complex (V1–V3) with anterolateral ST segment elevation (V1–V5, D1 and aVL). Creatine-kinase isoenzyme MB and Troponin I were elevated at arrival. Upon admission, the patient was normotensive but with signs of pulmonary congestion. Ventriculography showed anterolateral and apical hypokinesia with an ejection fraction of 21%. Coronari…
Alteration of Ventricular Fibrillation by Flecainide, Verapamil, and Sotalol
Background—The purpose of this study was to determine whether the myocardial electrophysiological properties are useful for predicting changes in the ventricular fibrillatory pattern. Methods and Results—Thirty-two Langendorff-perfused rabbit hearts were used to record ventricular fibrillatory activity with an epicardial multiple electrode. Under control conditions and after flecainide, verapamil, or d,l-sotalol, the dominant frequency (FrD), type of activation maps, conduction velocity, functional refractory period, and wavelength (WL) of excitation were determined during ventricular fibrillation (VF). Flecainide (1.9±0.3 versus 2.4±0.6 cm, P<0.05) and sotalol (2.1±0.3 versus 2.5±0.5 cm, P…
Trefoil factor-3 and galectin-4 as new candidates for prognostic biomarkers in ST-segment elevation myocardial infarction
Inhomogeneidad de respuesta del nodo auriculo-ventricular
Amplitud de distribución eritrocitaria y riesgo de mortalidad en pacientes con insuficiencia cardiaca aguda
Resumen Fundamento y objetivo El ancho de distribucion eritrocitaria (ADE) es una medida cuantitativa de la variabilidad del tamano de los eritrocitos circulantes utilizada clasicamente para el diagnostico diferencial de las anemias. En los ultimos anos, se ha sugerido que el ADE podria ser un marcador pronostico util en pacientes con insuficiencia cardiaca cronica. Sin embargo, es escasa la evidencia que respalda su papel en poblacion no seleccionada con insuficiencia cardiaca aguda (ICA), de manera independiente a los factores de riesgo establecidos. El objetivo del estudio fue establecer la asociacion entre el ADE y la mortalidad a largo plazo en pacientes ingresados por ICA. Pacientes y…