6533b820fe1ef96bd127992b
RESEARCH PRODUCT
Cocaine-induced coronary thrombosis and acute myocardial infarction
Vicente GonzálezJulio Núñez VillotaJuan Sanchis ForésLorenzo RubioEva Plancha BurgueraÁNgel Llácer EscorihuelaMauricio Pellicer BañulsVicent Bodí Perissubject
medicine.medical_specialtyEjection fractionbusiness.industryElectrocardiography in myocardial infarctionAnterior Descending Coronary Arterymedicine.diseaseThrombosisAnginaCoronary thrombosisRight coronary arterymedicine.arteryInternal medicinemedicineCardiologyMyocardial infarctionCardiology and Cardiovascular Medicinebusinessdescription
A 26-year-old man was admitted to our hemodynamic laboratory because of an anterior AMI and post myocardial infarction angina. He is an active smoker (10 cigarettes/day) and consumes inhaled cocaine during weekends (the last consumption of cocaine was 1 week ago). No others risk factors were recorded. Initial electrocardiogram shows sinus rhythm and anterior QS complex (V1–V3) with anterolateral ST segment elevation (V1–V5, D1 and aVL). Creatine-kinase isoenzyme MB and Troponin I were elevated at arrival. Upon admission, the patient was normotensive but with signs of pulmonary congestion. Ventriculography showed anterolateral and apical hypokinesia with an ejection fraction of 21%. Coronariography revealed a massive thrombosis and distal vasoconstriction of the left anterior descending coronary artery. Circumflex and right coronary artery were angiographically normals (Fig. 1). Recombinant tissue plasminogen activator was started by intracoronary infusion (50 mg) with additional 50 mg via systemic. Clinical evolution was satisfactory without new
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2004-09-01 | International Journal of Cardiology |