0000000000707031

AUTHOR

Ulrike Möllers

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Use of the polymerase chain reaction to demonstrate hepatitis B virus DNA in serum of children with chronic hepatitis B.

1992

The polymerase chain reaction was used to investigate the presence of hepatitis B virus DNA in sera of 61 children with chronic hepatitis B and negative results on dot biot hybridization tests. Our results demonstrate that most chronic carriers of hepatitis B surface antigen in childhood have hepatitis B virus DNA detectable by polymerase chain reaction in their serum and must be considered infectious.

AdolescentHepatitis B virus DNA polymeraseHepatitis B virus DNAmedicine.disease_causePolymerase Chain ReactionVirusHepatitis B virus PRE betalaw.inventionChronic hepatitislawMedicineHumansHepatitis B e AntigensHepatitis B AntibodiesChildPolymerase chain reactionHepatitis B virusbiologybusiness.industryInfantbiology.organism_classificationHepatitis BVirologyHepadnaviridaeChild PreschoolPediatrics Perinatology and Child HealthChronic DiseaseDNA ViralbusinessThe Journal of pediatrics
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