0000000000719902

AUTHOR

Ari Leppäniemi

showing 3 related works from this author

Global economic burden of unmet surgical need for appendicitis

2022

Abstract Background There is a substantial gap in provision of adequate surgical care in many low- and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capita…

surgical unmetneedno keywords listedsurgical unmetneed; appendicitis; global surgeryFinancial StressHealth Care Costsglobal surgeryAppendicitisFinancial StreHealth Care CostCost of IllnessHumansappendicitiseconomic burden surgerySurgeryAppendicitiHuman
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The association between appendicitis severity and patient age with appendiceal neoplasm histology—a population-based study

2022

Abstract Purpose Recent studies have reported alarming appendiceal tumor rates associated with complicated acute appendicitis, especially in patients presenting with a periappendicular abscess. However, the data on histology of appendiceal tumors among acute appendicitis patients is limited, especially in patient cohorts differentiating between uncomplicated and complicated acute appendicitis. We have previously reported the association of increased appendiceal tumor prevalence with complicated acute appendicitis in this population-based study. The objective of this secondary analysis was to evaluate the association of both appendicitis severity and patient age with appendiceal tumor histol…

UNCOMPLICATED ACUTE APPENDICITISAdultumpilisäketulehdusINTERVAL APPENDECTOMYANTIBIOTIC-THERAPYAdenocarcinoma3121 Internal medicineCONSERVATIVE TREATMENTNeuroendocrine tumorhistologiaMANAGEMENTAppendectomyHumansPseudomyxoma peritoneiINCREASED RISKMETAANALYSISMixed adeno-neuroendocrine carcinomapseudomyxoma peritoneiappendicitis severityappendiceal adenocarcinomaGastroenterologyneuroendokriiniset kasvaimetAppendiceal adenocarcinomaSERIESAppendicitisTUMORSAbscesskarsinoomatAppendiceal Neoplasms3121 General medicine internal medicine and other clinical medicineAcute Diseasemixed adeno-neuroendocrine carcinomaAppendicitis severityGoblet cell carcinomaneuroendocrine tumorgoblet cell carcinoma
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Global validation of the WSES Sepsis Severity Score for patients with complicated intra-abdominal infections : a prospective multicentre study (WISS …

2015

BACKGROUND: To validate a new practical Sepsis Severity Score for patients with complicated intra-abdominal infections (cIAIs) including the clinical conditions at the admission (severe sepsis/septic shock), the origin of the cIAIs, the delay in source control, the setting of acquisition and any risk factors such as age and immunosuppression. ----- METHODS: The WISS study (WSES cIAIs Score Study) is a multicenter observational study underwent in 132 medical institutions worldwide during a four-month study period (October 2014-February 2015). Four thousand five hundred thirty-three patients with a mean age of 51.2 years (range 18-99) were enrolled in the WISS study. ----- RESULTS: Univariate…

medicine.medical_specialtyInfections; Intra-abdominal; Sepsis; Septic shock:Ciências da Saúde [Ciências Médicas]Infections; Intra-abdominal; Sepsis; Septic shock; Surgery; Emergency MedicineCiências Médicas::Ciências da SaúdeSepsimedicine.medical_treatment/macromolecular substances030230 surgeryGUIDELINESInfectionsLikelihood ratios in diagnostic testingSepsisPERITONITIS03 medical and health sciencesPROGNOSTIC-FACTORS0302 clinical medicineInternal medicineSepsisSeptic shockMedicine and Health SciencesMANAGEMENTmedicineIntra-abdominalIntra-abdominal SepsisUnivariate analysisScience & TechnologyCOLONIC PERFORATIONReceiver operating characteristicbusiness.industrySeptic shockAbdominal InfectionImmunosuppression3126 Surgery anesthesiology intensive care radiologymedicine.disease3. Good healthSurgery030220 oncology & carcinogenesisInfections Intra-abdominal Sepsis; Septic shockEmergency MedicineSurgeryObservational studyInfectionbusinessSYSTEMResearch Article
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