0000000000725777

AUTHOR

Costanza D'angelo

showing 3 related works from this author

Transcranial magnetic resonance imaging-guided focused ultrasound treatment at 1.5 T: a retrospective study on treatment and patient-related paramete…

2020

Objective: To present a retrospective analysis of patient- and sonication-related parameters of a group of patients treated with a transcranial magnetic resonance imaging (MRI)-guided focused ultrasound (tcMRgFUS) system integrated with a 1.5-T MRI unit. Methods: The data obtained from 59 patients, who underwent the tcMRgFUS procedure from January 2015 to April 2019, were retrospectively reviewed for this study. The following data, among others, were mainly collected: skull density ratio (SDR), skull area (SA), number of available transducer elements (Tx), and estimated focal power at target (FP). For each of the four different treatment stages, we calculated the number of sonication proces…

Interventional magnetic resonance imagingMaterials Science (miscellaneous)medicine.medical_treatmentParkinson's diseaseEssential TremorBiophysicsGeneral Physics and Astronomy01 natural sciencesFocused ultrasound0103 physical sciencesmedicinePlane orientationInterventional Magnetic Resonance ImagingPhysical and Theoretical Chemistry010306 general physicsMathematical Physicsmedicine.diagnostic_testbusiness.industryThalamotomySettore MED/27 - NeurochirurgiaSettore MED/37 - NeuroradiologiaMagnetic resonance imagingRetrospective cohort studystereotaxic techniqueslcsh:QC1-999Settore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Parkinson Disease.essential tremor; high-intensity focused ultrasound ablation; interventional magnetic resonance imaging; Parkinson's disease; stereotaxic techniquesCoronal planeStereotaxic techniqueHigh-Intensity Focused Ultrasound AblationStereotaxic TechniqueSettore MED/26 - NeurologiaNuclear medicinebusinessSettore MED/36 - Diagnostica Per Immagini E Radioterapialcsh:Physics
researchProduct

Transcranial Magnetic Resonance Imaging-Guided Focused Ultrasound with a 1.5 Tesla Scanner: A Prospective Intraindividual Comparison Study of Intraop…

2021

Background: High-quality intraoperative imaging is needed for optimal monitoring of patients undergoing transcranial MR-guided Focused Ultrasound (tcMRgFUS) thalamotomy. In this paper, we compare the intraoperative imaging obtained with dedicated FUS-Head coil and standard body radiofrequency coil in tcMRgFUS thalamotomy using 1.5-T MR scanner. Methods: This prospective study included adult patients undergoing tcMRgFUS for treatment of essential tremor. Intraoperative T2-weighted FRFSE sequences were acquired after the last high-energy sonication using a dedicated two-channel FUS-Head (2ch-FUS) coil and body radiofrequency (body-RF) coil. Postoperative follow-ups were performed at 48 h usin…

Scannerhigh-intensity focused ultrasound ablationmedicine.medical_treatmentArticleFocused ultrasoundlcsh:RC321-571030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineMcNemar's testmedicinemagnetic resonance imagingimage qualityessential tremorlcsh:Neurosciences. Biological psychiatry. Neuropsychiatrymedicine.diagnostic_testSettore MED/27 - Neurochirurgiabusiness.industryThalamotomyGeneral NeuroscienceMR-guided focused ultrasoundSettore MED/37 - NeuroradiologiaMagnetic resonance imagingstereotaxic techniquesElectromagnetic coilStereotaxic techniquefocused ultrasoundSettore MED/26 - NeurologiaSettore MED/36 - Diagnostica Per Immagini E RadioterapiabusinessNuclear medicine030217 neurology & neurosurgeryRadiofrequency coilBrain Sciences
researchProduct

Imaging of Substantia Nigra in Parkinson's Disease: A Narrative Review.

2021

Parkinson’s disease (PD) is a progressive neurodegenerative disorder, characterized by motor and non-motor symptoms due to the degeneration of the pars compacta of the substantia nigra (SNc) with dopaminergic denervation of the striatum. Although the diagnosis of PD is principally based on a clinical assessment, great efforts have been expended over the past two decades to evaluate reliable biomarkers for PD. Among these biomarkers, magnetic resonance imaging (MRI)-based biomarkers may play a key role. Conventional MRI sequences are considered by many in the field to have low sensitivity, while advanced pulse sequences and ultra-high-field MRI techniques have brought many advantages, partic…

Parkinson's diseaseSettore MED/50 - Scienze Tecniche Mediche ApplicateSubstantia nigraNeurosciences. Biological psychiatry. NeuropsychiatryDiseaseStriatumReview030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineironneurodegenerative diseasemedicinemagnetic resonance imagingneurodegenerative diseasesmedicine.diagnostic_testPars compactabusiness.industryGeneral NeuroscienceradiomicSettore MED/37 - NeuroradiologiabiomarkersMagnetic resonance imagingmedicine.diseaseparkinsonian disordersnigrosome-1radiomicsParkinson’s diseasebiomarkerSettore MED/26 - NeurologiaDifferential diagnosisneuromelaninbusinessSettore MED/36 - Diagnostica Per Immagini E RadioterapiaNeuroscience030217 neurology & neurosurgeryDiffusion MRIRC321-571Brain sciences
researchProduct