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RESEARCH PRODUCT

Transcranial Magnetic Resonance Imaging-Guided Focused Ultrasound with a 1.5 Tesla Scanner: A Prospective Intraindividual Comparison Study of Intraoperative Imaging

Massimo MidiriMaurizio MarraleCostanza D'angeloLudovico La GruttaMarco D'amelioRoberto CannellaPaola FeracoDomenico Gerardo IacopinoGiuseppe SalvaggioPatrizia ToiaGiuseppe La TonaCesare Gagliardo

subject

Scannerhigh-intensity focused ultrasound ablationmedicine.medical_treatmentArticleFocused ultrasoundlcsh:RC321-571030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineMcNemar's testmedicinemagnetic resonance imagingimage qualityessential tremorlcsh:Neurosciences. Biological psychiatry. Neuropsychiatrymedicine.diagnostic_testSettore MED/27 - Neurochirurgiabusiness.industryThalamotomyGeneral NeuroscienceMR-guided focused ultrasoundSettore MED/37 - NeuroradiologiaMagnetic resonance imagingstereotaxic techniquesElectromagnetic coilStereotaxic techniquefocused ultrasoundSettore MED/26 - NeurologiaSettore MED/36 - Diagnostica Per Immagini E RadioterapiabusinessNuclear medicine030217 neurology & neurosurgeryRadiofrequency coil

description

Background: High-quality intraoperative imaging is needed for optimal monitoring of patients undergoing transcranial MR-guided Focused Ultrasound (tcMRgFUS) thalamotomy. In this paper, we compare the intraoperative imaging obtained with dedicated FUS-Head coil and standard body radiofrequency coil in tcMRgFUS thalamotomy using 1.5-T MR scanner. Methods: This prospective study included adult patients undergoing tcMRgFUS for treatment of essential tremor. Intraoperative T2-weighted FRFSE sequences were acquired after the last high-energy sonication using a dedicated two-channel FUS-Head (2ch-FUS) coil and body radiofrequency (body-RF) coil. Postoperative follow-ups were performed at 48 h using an eight-channel phased-array (8ch-HEAD) coil. Two readers independently assessed the signal-to-noise ratio (SNR) and evaluated the presence of concentric lesional zones (zone I, II and III). Intraindividual differences in SNR and lesional findings were compared using the Wilcoxon signed rank sum test and McNemar test. Results: Eight patients underwent tcMRgFUS thalamotomy. Intraoperative T2-weighted FRFSE images acquired using the 2ch-FUS coil demonstrated significantly higher SNR (R1 median SNR: 10.54

yearjournalcountryeditionlanguage
2021-01-04Brain Sciences
https://doi.org/10.3390/brainsci11010046