0000000000727139

AUTHOR

Anja Beschnitt

0000-0001-8949-4286

showing 2 related works from this author

Comparison of Two Solid-Phase Extraction (SPE) Methods for the Identification and Quantification of Porcine Retinal Protein Markers by LC-MS/MS

2018

Proper sample preparation protocols represent a critical step for liquid chromatography-mass spectrometry (LC-MS)-based proteomic study designs and influence the speed, performance and automation of high-throughput data acquisition. The main objective of this study was to compare two commercial solid-phase extraction (SPE)-based sample preparation protocols (comprising SOLA&micro

0301 basic medicineSwineGeneral Mathematicssample clean-upProteomicsMass spectrometry01 natural sciencesCatalysisRetinaArticlelcsh:ChemistryInorganic Chemistry03 medical and health scienceschemistry.chemical_compoundglaucoma animal modelZIPTIP® C18 pipette tipsTandem Mass SpectrometryLiquid chromatography–mass spectrometryTrifluoroacetic acidAnimalsSample preparationSolid phase extractionPhysical and Theoretical ChemistryEye Proteinslcsh:QH301-705.5Molecular BiologySpectroscopymass spectrometryZIPTIP<sup>®</sup> C18 pipette tipsReproducibilityChromatographyChemistryApplied Mathematics010401 analytical chemistryOrganic ChemistrySolid Phase ExtractionExtraction (chemistry)PipettebiomarkersGlaucomaGeneral Medicine0104 chemical sciencesComputer Science Applications030104 developmental biologylcsh:Biology (General)lcsh:QD1-999SOLAμTM HRP SPE spin platesPeptidesChromatography LiquidInternational Journal of Molecular Sciences
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Towards comprehensive non-target screening using heart-cut two-dimensional liquid chromatography for the analysis of organic atmospheric tracers in i…

2021

Abstract Non-target screening of secondary organic aerosol compounds in ice cores is used to reconstruct atmospheric conditions and sources and is a valuable tool to elucidate the chemical profiles of samples with the aim to obtain as much information as possible from one mass spectrometric measurement. The coupling of mass spectrometry to chromatography limits the results of a non-target screening to signals of compounds within a certain polarity range based on the utilized stationary phases of the columns. Comprehensive two-dimensional liquid chromatography (LCxLC) introduces a second column of different functionality to enable the analysis of a broader range of analytes. Conventional LCx…

AerosolsDetection limitChromatography Reverse-PhaseAnalyteChromatographyChemistryHydrophilic interaction chromatographyOrganic ChemistryGeneral MedicineRepeatabilityMass spectrometrySnowBiochemistryMass SpectrometryAnalytical ChemistryAerosolVolume (thermodynamics)Hydrophobic and Hydrophilic InteractionsChromatography LiquidJournal of Chromatography A
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