0000000000745148

AUTHOR

M. Palazzoadriano

showing 4 related works from this author

Drug-induced variations of the renin-angiotensin-aldosterone system in rats. I. Diuretics.

1977

Summary Groups of 10 rats were treated with diuretics (furosemide, hydrochlorotiazide, spironolactone, triamterene) under conditions of high or low plasma renin activity (PRA) brought about by administering distilled water or saline load, respectively. PRA, plasma aldosterone levels, urine aldosterone concentration as well as diuresis and Na+ and K+ excretion were

Malemedicine.medical_specialtyDiuresisPharmacologySpironolactonePlasma renin activityExcretionchemistry.chemical_compoundInternal medicineRenin–angiotensin systemReninmedicineAnimalsDiureticsAldosteronePharmacologyTriamtereneAldosteroneAngiotensin IISodiumFurosemideDiuresisRatsEndocrinologychemistrySpironolactonePotassiummedicine.drugTriamterenePharmacological research communications
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Number and functionality of beta-adrenergic receptors in the mouse lymphocytic P388 leukemia as a doxorubicin-sensitive and -resistant variant.

1992

Pharmacologymedicine.medical_specialtyAdrenergic receptorChemistryLeukemia P388Adrenergic beta-AntagonistsColforsinDrug ResistanceAlpha-1B adrenergic receptorAlpha-1A adrenergic receptorMiceEndocrinologyDoxorubicinInternal medicinePindololmedicineCancer researchCyclic AMPAnimalsDoxorubicinP388 leukemiaAlpha-1D adrenergic receptorReceptormedicine.drugPharmacological research
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Drug induced variations of the renin-angiotensin-aldosterone system in rats. II. Antihypertensives

1977

Summary Groups of male rats were treated with antihypertensive drugs (alpha-methyl-dopa, clonidine, propranolol, reserpine, diazoxide) which were administered under conditions causing the onset of high plasma renin activity (PRA) and high plasma and urine aldosterone levels, i.e. together with distilled water load (5% of body weight). Alpha-methyl-dopa and propranolol, which fail to significantly alter PRA and plasma aldosterone levels when administered without distilled water load, cause a marked decrease of plasma and urine aldosterone levels and of PRA when administered together with distilled water load, while diazoxide, and reserpine cause a marked increase of these values. Clonidine c…

Malemedicine.medical_specialtyBlood PressurePropranololPharmacologyPlasma renin activityInternal medicineReninRenin–angiotensin systemmedicineDiazoxideAnimalsAldosteroneAntihypertensive AgentsPharmacologyKidneyChemistryAngiotensin IIReserpineDiuresisRatsClonidinemedicine.anatomical_structureEndocrinologyVascular resistancemedicine.drugPharmacological Research Communications
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Modifications induced in the renin-angiotensin-aldo-sterone system of rats by alpha-blocking drugs.

1978

Summary The data reported in the present paper refer to quantitative variations of plasma renin activity and plasma aldosterone levels after administration of alpha-blocking agents, i.e. phentolamine, phenoxybenzamine and gihydroergotoxin derivatives, either to rats kept on a standard diet with water ad libitum or to rats receiving distilled water load, the latter treatment causing an increase of both plasma renin activity and plasma aldosterone levels if compared to control values. No strict correlation between (a) drug-induced modifications of plasma renin activity and plasma aldosterone levels and (b) blood pressure drop caused by the same drugs was shown to occur under either experiment…

Pharmacologymedicine.medical_specialtyChemistryPhenoxybenzamineAngiotensin IIBlood PressurePharmacologyPlasma renin activityBlood pressure dropRatsAlpha blockingPhentolamineEndocrinologyHigh plasmaInternal medicineRenin–angiotensin systemReninmedicineStandard dietAnimalsAldosteroneAdrenergic alpha-Antagonistsmedicine.drugPharmacological research communications
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